Progress in quantitative coronary arteriography

1. Front Matter

   Pages i-xiv

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2. Endothelial function

   1. Front Matter

      Pages 1-1

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   2. Endothelium control of vascular tone and growth: Potential role in coronary artery disease

      • Thomas F. Lüscher

      Pages 3-18

   3. Endothelial function in atherosclerosis

      • François Charbonneau, Ian T. Meredith, Todd J. Anderson, Marie Gerhard, Michael Dyce, Danielle Delagrange et al.

      Pages 19-30

3. QCA: Digital and cine coronary arteriography

   1. Front Matter

      Pages 31-31

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   2. Why and how should QCA systems be validated?

      • Johan H. C. Reiber, Gerhard Koning, Craig D. Von Land, Pieter M. J. Van Der Zwet

      Pages 33-48

   3. Percutaneous implantation of coronary stenosis phantoms in an anesthetized swine model to validate current quantitative angiography analysis systems

      • Jürgen Haase, David Keane, Carlo Di Mario, Javier Escaned, Yukio Ozaki, Cornelis J. Slager et al.

      Pages 49-65

   4. Comparison of accuracy and precision of quantitative coronary arterial analysis between cinefilm and digital systems

      • Johan H. C. Reiber, Craig D. Von Land, Gerhard Koning, Pieter M. J. Van Der Zwet, Ronald C. M. Van Houdt, Martin J. Schalij et al.

      Pages 67-85

   5. Angiographic core laboratory analyses of arterial phantom images: Comparative evaluations of accuracy and precision

      • Glenn J. Beauman, Johan H. C. Reiber, Gerhard Koning, Ronald C. M. Van Houdt, Robert A. Vogel

      Pages 87-104

   6. Task force of the ESC on digital cardiovascular imaging

      • Rüdiger Simon

      Pages 105-110

   7. Which media are most likely to solve the archival problem?

      • Jack T. Cusma, Thomas M. Bashore

      Pages 111-126

4. Intracoronary pressure, coronary blood flow and flow reserve

   1. Front Matter

      Pages 127-127

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   2. Control and mechanics of the coronary circulation

      • Jos A. E. Spaan

      Pages 129-140

   3. Possibilities and limitations of myocardial flow reserve

      • Felix Zijlstra, Petr Widimsky, Harry Suryapranata

      Pages 141-159

   4. Myocardial flow reserve: On-line versus off-line assessment techniques

      • Marc M. J. M. Van Der Linden, Jürgen Haase, Patrick W. Serruys

      Pages 161-171

   5. On-line assessment of myocardial flow reserve

      • Martin J. Schalij, Mariken J. A. Geldof, Pieter M. J. Van Der Zwet, Enno T. Van Der Velde, Els M. Nagtegaal, Volkert Manger Cats et al.

      Pages 173-189

   6. Relationship between transstenotic pressure gradients and coronary angiographic parameters

      • Håkan Emanuelsson, Carl Lamm, Michal Dohnal

      Pages 191-206

   7. Intracoronary pressure measurements for calculation of flow reserve

      • Nico H. J. Pijls, Bernard De Bruyne, Sherif El Biltagui, Mamdouh El Gamal, Hans J. R. M. Bonnier, Guy R. Heyndrickx et al.

      Pages 207-226

   8. Intracoronary Doppler flow velocity in coronary interventions

      • Morton J. Kern

      Pages 227-246

   9. The instantaneous hyperemic pressure-flow relationship in conscious humans

      • Carlo Di Mario, Rob Krams, Robert Gil, Nicolas Meneveau, Patrick W. Serruys

      Pages 247-268

This is the fifth volume in this series on quantitative coronary arteriography (QCA) published over the last nine years. Research and applications in this exciting, field are covered in a total of 26 chapters by world renowned experts. This book is subdivided into a total of 6 parts, each emphasizing the latest progress in these respective fields. In Part One a comprehensive overview is given of the current knowledge and research in endothelial function, which is of eminent importance for the further understanding of the pathophysiology of coronary artery disease in patients. Fortunately, the use of QCA tools is not limited anymore to leading research institutes; over the last several years these tools have been installed in many cardiology centers world wide. To understand the current possibili­ ties, limitations and future expectations of QCA, several relevant topics are presented in Part Two. First of all, the questions about why and how QCA systems should be validated both at the development site and at the appli­ cation sites, and whether data from different vendors and core laboratories can be pooled, are discussed. As the X-ray cardiovascular world steadily moves into the digital imaging era, differences and similarities between the conventional cinefilm and the modern digital approaches are presented. Cur­ rently. the widespread use of digital imaging is still hindered by the lack of proper archival and exchange media. Requirements and possible solutions for this problem are handled in this section as well.

• angiography
• atherosclerosis
• cardiovascular
• circulation
• coronary artery disease
• fluorescence
• ultrasound

• Laboratory for Clinical and Experimental Image Processing, Department of Diagnostic Radiology and Nuclear Medicine, University Hospital Leiden, The Netherlands

  Johan H. C. Reiber

• Catheterization Laboratory, Thorax Center, Erasmus University, Rotterdam, The Netherlands

  Patrick W. Serruys

Policies and ethics