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Table of contents (30 chapters)
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Front Matter
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Coronary heart disease in families and populations
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Front Matter
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Coronary heart disease risk factors and their genetics
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Front Matter
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Monogenic traits affecting coronary heart disease incidence
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Front Matter
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About this book
This book consolidates the available evidence for the roles of genetics in atherosclerosis, its correlates and its sequelae. It presents and discusses the methodology currently used to elucidate the role of genetics. Separate parts focus on evidence of familial aggregation and ethnic variability of the disease and on monogenic and polygenic inheritance modes including all the recent findings and innovation. The book also contains chapters on the genetic aspects of vessel wall processes, such as early structural findings in histological studies and the variability of coronary anatomic patterns. Polymorphisms at the DNA level (RFLP) are detailed and reviewed. Directions for future research in the exciting and fast developing realm of genetic epidemiology are outlined and the major preventive and public health implications are discussed.
Genetic Factors in Coronary Heart Disease provides a systematic review of findings, integrated to offer a comprehensive summary and stepping stone for future research. It will be of interest to investigators in atherosclerosis, genetics, epidemiology, biostatistics, cardiology and public health.
Editors and Affiliations
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Sackler Medical Faculty, Epidemiology and Biostatistics, the Neufeld Cardiac Research Institute, Sheba Medical Center and Tel Aviv University, Israel
Uri Goldbourt
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Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institute and Division of Cardiovascular Medicine, Department of Internal Medicine, Karolinska Hospital, Stockholm, Sweden
Ulf Faire
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Institute of Medical Genetics, Department of Medical Genetics, Ullevål University Hospital, Oslo, Norway
Kåre Berg
Bibliographic Information
Book Title: Genetic factors in coronary heart disease
Editors: Uri Goldbourt, Ulf Faire, Kåre Berg
Series Title: Developments in Cardiovascular Medicine
DOI: https://doi.org/10.1007/978-94-011-1130-0
Publisher: Springer Dordrecht
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media Dordrecht 1994
Hardcover ISBN: 978-0-7923-2752-3Published: 30 September 1994
Softcover ISBN: 978-94-010-4494-3Published: 11 October 2012
eBook ISBN: 978-94-011-1130-0Published: 06 December 2012
Series ISSN: 0166-9842
Edition Number: 1
Number of Pages: XIV, 463
Topics: Cardiology, Epidemiology