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  • © 1994

Self-Production of Supramolecular Structures

From Synthetic Structures to Models of Minimal Living Systems

Part of the book series: Nato Science Series C: (ASIC, volume 446)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xvii
  2. Historical and Philosophical Perspectives

    1. Front Matter

      Pages 1-1
    2. On Defining Life

      • F. J. Varela
      Pages 23-31
    3. A Few Precautionary Words Concerning Terminology

      • G. R. Fleischaker
      Pages 33-41
  3. Template Chemistry

    1. Front Matter

      Pages 43-43
    2. Molecular Replication: From Minimal to Complex Systems

      • D. Sievers, T. Achilles, J. Burmeister, S. Jordan, A. Terfort, G. Von Kiedrowski
      Pages 45-64
    3. Template-Directed Synthesis of Oligomers: Kinetic vs. Thermodynamic Control

      • J. T. Goodwin, P. Luo, J. C. Leitzel, D. G. Lynn
      Pages 99-104
  4. Chirality and Replication

    1. Front Matter

      Pages 105-105
    2. Chirality and the First Self-Replicating Molecules

      • Alan W. Schwartz, M. J. Van Vliet
      Pages 107-114
  5. The RNA World

    1. Front Matter

      Pages 125-125
    2. Models for the Autocatalytic Replication of RNA

      • Lori Giver, Susan Lato, Andrew Ellington
      Pages 137-146
    3. RNA Species that Multiply Indefinitely with RNA Polymerase

      • Christof K. Biebricher
      Pages 147-156
  6. The Cell View and Cell Models

    1. Front Matter

      Pages 177-177

About this book

How did life begin on the Earth? The units of life are cells, which can be defined as bounded systems of molecules that capture energy and nutrients from the environment -- systems that expand, reproduce, and evolve over time, often into more complex systems. This book is the proceedings of a unique meeting, sponsored by NATO and held in Maratea, Italy, that brought together for the first time an international group of investigators who share an interest in how molecules self-assemble into supramolecular structures, and how those structures may have contributed to the origin of life.
The book is written at a moderately technical level, appropriate for use by researchers and by students in upper-level undergraduate and graduate courses in biochemistry and molecular biology. The overall interest of its subject matter provides an excellent introduction for students who wish to understand how the foundational knowledge of chemistry and physics can be applied to one of the most fundamental questions now facing the scientific community.
The editors are pioneers in defining what we mean by the living state, particularly the manner in which simple molecular systems can assume complex associations and functions, including the ability to reproduce. Each chapter of the book presents an up-to-date report of highly significant research. Two of the authors received medals from the National Academy of Science USA in 1994, and other research reported in the book has been featured in internationally recognized journals such Scientific American, Time, and Discover.

Editors and Affiliations

  • Center for the Philosophy & History of Science, Boston University, Boston, USA

    Gail R. Fleischaker

  • Departimento di Chimica, Università degli Studi di Milano, Milano, Italy

    Stefano Colonna

  • Institut für Polymere, ETH-Zürich, Switzerland

    Pier Luigi Luisi

Bibliographic Information

  • Book Title: Self-Production of Supramolecular Structures

  • Book Subtitle: From Synthetic Structures to Models of Minimal Living Systems

  • Editors: Gail R. Fleischaker, Stefano Colonna, Pier Luigi Luisi

  • Series Title: Nato Science Series C:

  • DOI: https://doi.org/10.1007/978-94-011-0754-9

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1994

  • Hardcover ISBN: 978-0-7923-3163-6Published: 31 October 1994

  • Softcover ISBN: 978-94-010-4324-3Published: 03 October 2013

  • eBook ISBN: 978-94-011-0754-9Published: 06 December 2012

  • Series ISSN: 1389-2185

  • Edition Number: 1

  • Number of Pages: XVII, 317

  • Topics: Nuclear Chemistry, Polymer Sciences, Bioorganic Chemistry, Organic Chemistry, Biochemistry, general, Inorganic Chemistry

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access