Skip to main content
  • Book
  • © 1995

Cell Culture Engineering IV

Improvements of Human Health

Part of the book series: Current Applications of Cell Culture Engineering (CACC, volume 1)

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (39 chapters)

  1. Front Matter

    Pages i-vii
  2. Introduction

    • Barry C. Buckland
    Pages 1-2
  3. Selecting and designing cell lines for improved physiological characteristics

    • J. R. Birch, R. C. Boraston, H. Metcalfe, M. E. Brown, C. R. Bebbington, R. P. Field
    Pages 11-16
  4. Diverse effects of essential (n-6 and n-3) fatty acids on cultured cells

    • Stephanos I. Grammatikos, Papasani V. Subbaiah, Thomas A. Victor, William M. Miller
    Pages 31-50
  5. Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production

    • Masaki Kobayashi, Satoru Kato, Takeshi Omasa, Suteaki Shioya, Ken-ichi Suga
    Pages 51-56
  6. Growth rate suppression of cultured mammalian cells enhances protein productivity

    • Kazunari Takahashi, Satoshi Tereda, Hiroshi Ueda, Fusao Makishima, Eiji Suzuki
    Pages 57-64
  7. Growth and interferon-γ production in batch culture of CHO cells

    • V. Leelavatcharamas, A. N. Emery, M. Al-Rubeai
    Pages 65-71
  8. Metabolic and kinetic studies of hybridomas in exponentially fed-batch cultures using T-flasks

    • Ana E. Higareda, Lourival D. Possani, Octavio T. Ramírez
    Pages 73-86
  9. Adaptation of mammalian cells to non-ammoniagenic media

    • Michael Butler, Andrew Christie
    Pages 87-94
  10. Effect of endogenous proteins on growth and antibody productivity in hybridoma batch cultures

    • Patrick J. Farrell, Nicolas Kalogerakis, Leo A. Behie
    Pages 95-102
  11. Extracellular insulin degrading activity creates instability in a CHO-based batch-refeed continuous process

    • Denis Drapeau, Yen-Tung Luan, Joanne A. Popoloski, D. Troy Richards, David C. Cohen, Martin S. Sinacore et al.
    Pages 103-109
  12. Low temperature cultivation — A step towards process optimisation

    • Ralf Weidemann, Andreas Ludwig, Gerlinde Kretzmer
    Pages 111-116
  13. Induction of apoptosis in oxygen-deprived cultures of hybridoma cells

    • Sylvain Mercille, Bernard Massie
    Pages 117-128
  14. Recombinant protein expression in a Drosophila cell line: comparison with the baculovirus system

    • A. R. Bernard, T. A. Kost, L. Overton, C. Cavegn, J. Young, M. Bertrand et al.
    Pages 139-144
  15. Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells

    • Alain Garnier, Johanne Côté, Isabelle Nadeau, Amine Kamen, Bernard Massie
    Pages 145-155
  16. Relationship between oxygen uptake rate and time of infection of Sf9 insect cells infected with a recombinant baculovirus

    • T. K. Kathy Wong, Lars K. Nielsen, Paul F. Greenfield, Steven Reid
    Pages 157-167
  17. Optimization of vaccine production for animal health

    • W. Noe, R. Bux, W. Berthold, W. Werz
    Pages 169-176

About this book

Cell Culture Engineering IV, Improvements of Human Health covers the latest approaches to improving the cell host through improved understanding of the molecular biology, the development of novel vaccines, approaches to bioreactor design and operation, monitoring techniques in process control and quality related topics. The work was carefully put together as one result of the Cell Culture Engineering IV Meeting held in San Diego, U.S.A. in 1994, however, the book may not be perceived as a proceedings volume - the criteria of the book series apply.
For cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to cell culture engineering, working in the academic environment, as well as in (biotechnology or pharmaceutical) industry.

Editors and Affiliations

  • Merck Research Laboratories, Biochemical Process R&D, Rahway, USA

    Barry C. Buckland

Bibliographic Information

  • Book Title: Cell Culture Engineering IV

  • Book Subtitle: Improvements of Human Health

  • Editors: Barry C. Buckland, John G. Aunins, Theodora A. Bibila, Wei-Shou Hu, David K. Robinson, Weichang Zhou

  • Series Title: Current Applications of Cell Culture Engineering

  • DOI: https://doi.org/10.1007/978-94-011-0257-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1995

  • Hardcover ISBN: 978-0-7923-3353-1Published: 31 January 1995

  • Softcover ISBN: 978-94-010-4114-0Published: 13 November 2012

  • eBook ISBN: 978-94-011-0257-5Published: 29 June 2013

  • Series ISSN: 1386-2928

  • Edition Number: 1

  • Number of Pages: V, 376

  • Topics: Animal Anatomy / Morphology / Histology, Animal Biochemistry, Biotechnology

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access