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Immunology of Endocrine Diseases

  • Book
  • © 1986

Overview

Editors:
  1. Alan M. McGregor

    1. Department of Medicine, University of Wales College of Medicine, Cardiff, Wales, UK

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Part of the book series: Immunology and Medicine (IMME, volume 3)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xii
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  2. The Mouse Model of Autoimmune Thyroid Disease

    • Y. M. Kong
    Pages 1-24

  3. Recent Developments in the in vitro Bioassay of TSH and Thyroid-Stimulating Antibodies

    • N. J. Marshall, P. A. Ealey
    Pages 25-49

  4. Immunoglobulins Affecting Thyroid Growth

    • H. A. Drexhage, R. D. van der Gaag
    Pages 51-71

  5. Islet Cell Antibodies

    • S. Baekkeskov, M. Christie, Å. Lernmark
    Pages 73-88

  6. Insulin Antibodies

    • A. Kurtz
    Pages 89-102

  7. Immunogenetics of Diabetes

    • A. H. Barnett
    Pages 103-121

  8. Immunogenetics of Graves’ Disease

    • H. Tamai, L. F. Kumagai, S. Nagataki
    Pages 123-141

  9. HLA-DR Antigen Expression and Autoimmunity

    • A. P. Weetman
    Pages 143-159

  10. Observations on Graves’ Ophthalmopathy; Pathology and Pathogenesis

    • R. M. Pope, M. E. Ludgate, A. M. McGregor
    Pages 161-179

  11. Autoimmune Thyroid Disease in Pregnancy and the Postpartum Period

    • R. Jansson, A. Karlsson
    Pages 181-196
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Keywords

About this book

Nineteen eighty-six is a most appropriate year in which to be writing about developments in the organ-specific, autoimmune endocrine diseases. It celebrates the publication 30 years ago in 1956 of the classic papers of Roitt and Doniach and their co-workers I , and of Rose and Witebsky2 and Adams 3 and Purves . These three sets of fundamental observations provided the initial building blocks upon which much of what has been established in the field in the last 30 years was built. No publication of this nature on endocrine autoimmune disease can cover every aspect of the subject. I have chosen to highlight the organs (thyroid and pancreeas) which have attracted the most attention, and the areas of work within these fields within which most research effort is currently focused. There are still some gaps; the insulin and TSH receptors are not considered, nor in any detail are the role of cytotoxic mechanisms in mediating gland destruction. Molecular biology will undoubtedly in the next few years clarify once and for all the controversy that surrounds the structure of the TSH receptor and T cell cloning, the role of cell-mediated cytotoxicity. The pathogenetic mechanisms underlying autoimmunity are increasingly well understood and the search for the aetiology has begun.

Editors and Affiliations

  • Department of Medicine, University of Wales College of Medicine, Cardiff, Wales, UK

    Alan M. McGregor

Bibliographic Information

  • Book Title: Immunology of Endocrine Diseases

  • Editors: Alan M. McGregor

  • Series Title: Immunology and Medicine

  • DOI: https://doi.org/10.1007/978-94-009-4171-7

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1986

  • Softcover ISBN: 978-94-010-8352-2Published: 14 October 2011

  • eBook ISBN: 978-94-009-4171-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 224

  • Topics: Immunology, Diabetes

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