New Developments in Quantitative Coronary Arteriography

1. Front Matter

   Pages i-xviii

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2. Methodological Developments in Coronary Arterial Stenosis Quantitation

   1. Digital imaging systems for coronary angiography

      • Rüdiger Brennecke

      Pages 1-12

   2. Optimal biplane imaging of coronary segments with computed triple orthogonal projections

      • Helmut Wollschläger, A. M. Zeiher, P. Lee, U. Solzbach, T. Bonzel, H. Just

      Pages 13-21

   3. Accurate densitometric quantification requires strict attention to the physical characteristics of X-ray imaging

      • J. Martin Pfaff, S. Whiting, N. E. Eigler, J. S. Forrester

      Pages 22-33

   4. Morphologic and densitometric quantitation of coronary stenoses; an overview of existing quantitation techniques

      • Johan H. C. Reiber

      Pages 34-88

   5. Intravenous digital coronary angiography — a review of technical considerations and recent results

      • Edward J. Toggart, W. Peppler, N. Hangiandreou, C. Mistretta

      Pages 89-99

   6. Assessment of the anatomic and functional severity of coronary arterial stenosis: new measuring techniques using high-frequency epicardial echocardiography and Doppler ultrasound

      • Richard E. Kerber, D. D. McPherson, S. J. Sirna, M. L. Marcus, L. F. Hiratzka, R. A. Kieso

      Pages 100-114

3. Validations and Clinical Applications of Quantitative Coronary Arteriography

   1. On the accuracy of densitometric measurements of coronary artery stenosis based on Lambert-Beer’s absorption law

      • Pierre-André Doriot, W. Rutishauser

      Pages 115-124

   2. Morphologic and physiologic validation of quantitative coronary arteriography utilizing digital methods

      • G. B. John Mancini

      Pages 125-141

   3. Comparison of automated edge detection and videodensitometric quantitative coronary arteriography

      • Robert A. Vogel, M. Sanz, G. B. J. Mancini

      Pages 142-152

   4. Issues of validation in quantitative coronary angiography

      • David M. Herrington, G. A. Walford, T. A. Pearson

      Pages 153-166

   5. Early regression and late progression in coronary artery lesions in the first 3 months following coronary angioplasty

      • Kevin J. Beatt, H. E. Luijten, J. H. C. Reiber, P. W. Serruys

      Pages 167-180

   6. How to assess the immediate results of PTCA. Should we use pressure gradient, flow reserve or minimal luminal cross-sectional area?

      • Patrick W. Serruys, F. Zijlstra, Y. Juillière, P. J. De Feyter, M. Vd Brand, H. Suryapranata et al.

      Pages 181-206

4. Assessment of Coronary Flow and Myocardial Perfusion

   1. Theoretical and practical aspects of digital angiography for quantitative coronary flow studies

      • Joachim H. Bürsch

      Pages 207-224

   2. Three-dimensional reconstruction and flow measurements of coronary arteries using multi-view digital angiography

      • Dennis L. Parker, J. Wu, D. L. Pope, R. Van Bree, G. R. Caputo, H. W. Marshall

      Pages 225-247

5. The Current Role of Coronary Angioscopy

   1. Coronary angioscopy during cardiac catheterization and surgery

      • Thomas Wendt, L. Eckel, M. Kaltenbach, E. Krause, T. Müller, N. Radünz et al.

      Pages 248-260

   2. The angioscopic view of atherosclerotic cardiovascular disease

      • Warren Grundfest, F. Litvack, J. Segalowitz, D. Glick, F. Mohr, A. Hickey et al.

      Pages 261-270

6. The Stent, A Breakthrough?

   1. Percutaneously implantable endo-coronary prosthesis

      • Jacques Puel, F. Joffre, H. Rousseau, A. Courtault, M. Galinier, J. Haddad et al.

      Pages 271-277

   2. A coronary endoprosthesis to prevent restenosis and acute occlusion after percutaneous angioplasty: One and a half year of clinical experience

      • Ulrich Sigwart, S. Golf, U. Kaufmann, L. Kappenberger

      Pages 278-284

7. Back Matter

   Pages 285-292

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There are few techniques that have influenced therapeutic strategies in modem cardiology to a similar extent as coronary arteriography. Bypass surgery as well as transluminal coronary angioplasty would not have been possible without coronary angiography serving as a 'midwife' in their evolu­ tion. Despite the widespread and long-standing use in clinical practice, however, the interpretation of coronary angiograms has not changed very much since the early days. Most angiogr~s are still reviewed in a visual and semi-quantitative and thus often very subjective way. In the face of an almost exploding field for interventional catheterization including thrombolysis, balloon dilatation, and other rapidly evolving techniques for transluminal revascularization or recanalization, a more detailed and quantitative analysis of coronary arteriograms is urgently required. In addition to the delineation of coronary morphology, we need dynamic and functional information about flow and perfusion to understand the physiological significance of anatomic abnormalities. Coronary arteriography contains and can provide most of this information. With the application of appropriate techniques, it can be made available in the catheterization laboratory even during the patient's investiga­ tion, thus facilitating and improving clinical decision making. Objective and reproducible analysis will furthermore enhance our understanding about the pathophysiology of coronary disease.

• PTCA
• Stent
• cardiovascular
• orthogonal projections
• ultrasound

• Institute of Cardiology, Thoraxcenter, Erasmus University, Rotterdam, The Netherlands

  Johan H. C. Reiber, Patrick W. Serruys

• University Hospital Dijkzigt, Rotterdam, The Netherlands

  Johan H. C. Reiber, Patrick W. Serruys

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