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Genome Evolution

Gene and Genome Duplications and the Origin of Novel Gene Functions

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xv
  2. Early events in genome evolution

    1. Detection of gene duplications and block duplications in eukaryotic genomes

      • Wen-Hsiung Li, Zhenglong Gu, Andre R. O. Cavalcanti, Anton Nekrutenko
      Pages 27-34
    2. The evolutionary demography of duplicate genes

      • Michael Lynch, John S. Conery
      Pages 35-44
  3. Debating the 2R and 3R genome duplication hypotheses

    1. Are all fishes ancient polyploids?

      • Yves Van de Peer, John S. Taylor, Axel Meyer
      Pages 65-73
    2. More genes in vertebrates?

      • Peter W. H. Holland
      Pages 75-84
    3. The 2R hypothesis and the human genome sequence

      • Karsten Hokamp, Aoife McLysaght, Kenneth H. Wolfe
      Pages 95-110
  4. Plant genome evolution

    1. Introns in, introns out in plant gene families: a genomic approach of the dynamics of gene structure

      • Alain Lecharny, Nathalie Boudet, Isabelle Gy, Sébastien Aubourg, Martin Kreis
      Pages 111-116
    2. Investigating ancient duplication events in the Arabidopsis genome

      • Jeroen Raes, Klaas Vandepoele, Cedric Simillion, Yvan Saeys, Yves Van de Peer
      Pages 117-129
  5. Case studies

    1. Evolution of signal transduction by gene and genome duplication in fish

      • Jean-Nicolas Volff, Manfred Schartl
      Pages 139-150
    2. Dopamine receptors for every species: Gene duplications and functional diversification in Craniates

      • Stéphane Le Crom, Marika Kapsimali, Pierre-Olivier Barôme, Philippe Vernier
      Pages 161-176
    3. Nuclear receptors are markers of animal genome evolution

      • Héctor Escrivá García, Vincent Laudet, Marc Robinson-Rechavi
      Pages 177-184
    4. The fates of zebrafish Hox gene duplicates

      • Chris Jozefowicz, James McClintock, Victoria Prince
      Pages 185-194
    5. Phylogenetic analysis of the mammalian Hoxc8 non-coding region

      • Chang-Bae Kim, Cooduvalli S. Shashikant, Kenta Sumiyama, Wayne C. H. Wang, Chris T. Amemiya, Frank H. Ruddle
      Pages 195-199

About this book

In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances.

This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation.

This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.

Editors and Affiliations

  • University of Konstanz, Germany

    Axel Meyer

  • Ghent University, Belgium

    Yves Peer

Bibliographic Information

  • Book Title: Genome Evolution

  • Book Subtitle: Gene and Genome Duplications and the Origin of Novel Gene Functions

  • Editors: Axel Meyer, Yves Peer

  • DOI: https://doi.org/10.1007/978-94-010-0263-9

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 2003

  • Hardcover ISBN: 978-1-4020-1021-7Published: 30 April 2003

  • Softcover ISBN: 978-94-010-3957-4Published: 31 October 2012

  • eBook ISBN: 978-94-010-0263-9Published: 28 June 2011

  • Edition Number: 1

  • Number of Pages: XV, 237

  • Additional Information: Reprinted from JOURNAL OF STRUCTURAL AND FUNCTIONAL GENOMICS, 3:1-4

  • Topics: Evolutionary Biology, Biochemistry, general, Human Genetics

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access