Overview
- Authors:
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O. J. J. Cluysenaer
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Department of Medicine, Division of Gastroenterology, Sint Radboud Hospital, University of Nijmegen, The Netherlands
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J. H. M. Tongeren
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Department of Medicine, Division of Gastroenterology, Sint Radboud Hospital, University of Nijmegen, The Netherlands
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Table of contents (12 chapters)
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Front Matter
Pages I-XIII
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 1-12
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 13-17
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 18-29
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 30-52
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 53-85
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 86-109
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 110-177
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 178-186
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 187-209
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 210-217
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 218-231
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- O. J. J. Cluysenaer, J. H. M. Van Tongeren
Pages 232-237
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Back Matter
Pages 238-279
About this book
For at least three centuries, Holland has been at the centre of research on intestinal malabsorption. In the 17th and 18th centuries, early descriptions of coeliac disease and tropical sprue were published by physicians trained in Holland, and it was in 1950 that Dicke published his painstaking and vital observations that coeliac disease in children was caused by the inges tion of wheat flour. Subsequent careful work with van de Kamer and Weijers showed that the harmful agent was gluten. Since these discoveries were made, research in intestinal malabsorption, particularly in the adult, has continued in several centres in Holland. At Nijmegen, for example, dr. Cluysenaer, dr. van Tongeren and their as sociates have been involved in long-term studies of patients with intestinal disease for the past fifteen years. In this book they describe their experience of the investigation and treatment of fifty patients with the adult form of coeliac disease. Their monograph gives an account of the history, definition and incidence of the disorder, and then goes on to undertake a critical review of the pathogenesis of the coeliac lesion. Before embarking on the different patterns of malabsorption seen in adult coeliac disease, the authors describe the normal small intestine, its morphology and function.