Immunological Aspects of Gastroenterology

1. Front Matter

   Pages i-xi

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2. Intestinal mucosal innate immunity

   • R. N. Cunliffe, Y. R. Mahida

   Pages 1-33

3. Adaptive immunity in the gastrointestinal tract

   • A. J. S. Macpherson, K. J. Maloy

   Pages 35-53

4. Role of epithelial cells in mucosal immunobiology

   • K. Luedtke-heckenkamp, H. C. Reinecker

   Pages 55-74

5. Molecular immunology of mucosal T cells

   • L. J. Saubermann, R. S. Blumberg

   Pages 75-95

6. Bacterial virulence mechanisms and the host immune response to enteric infection

   • J. D. Edgeworth, P. J. Sansonetti

   Pages 97-129

7. HIV infection of the gastrointestinal tract

   • T. Schneider, V. Zeitz

   Pages 131-152

8. Immunological aspects of Helicobacter pylori infection

   • H. J. Windle, A. M. Terrés, D. Kelleher

   Pages 153-175

9. Molecular pathogenesis and clinical immmunology of coeliac disease

   • P. J. Ciclitira

   Pages 177-215

10. Immunopathophysiology of inflammatory bowel disease

    • S. Schreiber

    Pages 217-239

11. Rodent models of chronic intestinal inflammation

    • Y. R. Mahida

    Pages 241-263

12. Regulation of intestinal immune responses to local antigens: oral tolerance vs immunopathology

    • A. McI. Mowat

    Pages 265-312

13. Mucosal immunisation and vaccines

    • M. Fielder, D. J. M. Lewis

    Pages 313-335

14. Transplantation immunology and the gut

    • F. Shanahan

    Pages 337-351

15. Back Matter

    Pages 353-359

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Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology.
The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.

• HIV
• HIV infection
• Transplantation
• antigen
• bacteria
• infection
• infections
• pathophysiology
• physiology
• virus
• infectious diseases

• University of Nottingham and Queen’s Medical Centre, Nottingham, UK

  Y. R. Mahida

Yashwant Madida is a Professor in Medicine and Consultant Physician/Gastroenterologist at the University of Nottingham and University Hospital, Queen's Medical Centre in Nottingham. He obtained his medical qualification from the University of Liverpool and has worked in London, Oxford, and Boston (USA). His main areas of interest are inflammatory disease of the gastrointestinal tract and cellular and molecular aspects of host-microbial interactions.

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