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Clinical Aspects of Albumin

  • Book
  • © 1978

Overview

Editors:
  1. S. H. Yap

    1. St. Radboud Hospital, University of Nijmegen and Albert Einstein College of Medicine, New York, USA

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  2. C. L. H. Majoor

    1. St. Radboud Hospital, University of Nijmegen, Netherlands

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  3. J. H. M. Tongeren

    1. St. Radboud Hospital, University of Nijmegen, Netherlands

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xii
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  2. The mechanism of protein biosynthesis

    • H. Bloemendal
    Pages 1-8

  3. Intracellular transport and secretion of proteins

    • A. M. Stadhouders
    Pages 9-24

  4. Molecular approach to the study of albumin synthesis

    • D. A. Shafritz, R. K. Strair, S. H. Yap
    Pages 25-48

  5. Rat liver albumin messenger RNA: subcellular distribution and changes in various models of metabolic diseases

    • S. H. Yap, R. K. Strair, D. A. Shafritz
    Pages 49-66

  6. Regulation of albumin synthesis

    • M. Oratz, M. A. Rothschild, S. S. Schreiber
    Pages 67-80

  7. Distribution and degradation of albumin

    • S. Jarnum, K. B. Jensen
    Pages 81-96

  8. Serum albumin in clinical practice: A historical review

    • C. L. H. Majoor
    Pages 97-116

  9. Causes of hypoalbuminemia

    • J. H. M. Van Tongeren, O. J. J. Cluysenaer, C. B. H. Lamers, P. H. M. De Mulder, S. H. Yap
    Pages 117-133

  10. The colloid osmotic pressure in cardiac disease

    • J. Gerbrandy, S. J. Smith, H. G. Van Eijk
    Pages 134-148

  11. Changes in plasma albumin concentration and drug action

    • E. J. Ariëns, A. M. Simonis
    Pages 149-171

  12. Preparation and control of serum albumin

    • H. W. Krijnen
    Pages 172-174

  13. Utilization pattern of plasma protein and albumin

    • Y. A. Hekster, R. W. M. M. Langenhoff, L. J. B. Zuidgeest, J. C. L. H. Benneker, E. Van Der Kleijn
    Pages 175-184

  14. Use and abuse of albumin and plasma-protein infusions in acute clinical situations

    • R. J. A. Goris
    Pages 185-193

  15. Use and abuse of albumin and plasma protein infusions in chronic protein depletion

    • C. B. H. W. Lamers
    Pages 194-199

  16. Back Matter

    Pages 200-203
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Keywords

About this book

Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans­ port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro­ tic syndrome as being a result of a very low level of serum albumin. Al­ though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.

Editors and Affiliations

  • St. Radboud Hospital, University of Nijmegen and Albert Einstein College of Medicine, New York, USA

    S. H. Yap

  • St. Radboud Hospital, University of Nijmegen, Netherlands

    C. L. H. Majoor, J. H. M. Tongeren

Bibliographic Information

  • Book Title: Clinical Aspects of Albumin

  • Editors: S. H. Yap, C. L. H. Majoor, J. H. M. Tongeren

  • DOI: https://doi.org/10.1007/978-94-009-9744-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishers bv, The Hague. 1978

  • Softcover ISBN: 978-94-009-9746-2Published: 05 November 2011

  • eBook ISBN: 978-94-009-9744-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 217

  • Topics: Gastroenterology, Intensive / Critical Care Medicine

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