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Carcinogenesis: Fundamental Mechanisms and Environmental Effects

Proceedings of the Thirteenth Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, April 28 – May 2, 1980

  • Conference proceedings
  • © 1980

Overview

Editors:
  1. Bernard Pullman

    1. Institut de Biologie Physico-Chimique (Fondation Edmond de Rothschild), Université Pierre et Marie Curie (Paris VI), Paris, France

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  2. Paul O. P. Ts’o

    1. The Johns Hopkins University, Baltimore, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Harry Gelboin

    1. National Cancer Institute, Bethesda, USA

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Part of the book series: Jerusalem Symposia (JSQC, volume 13)

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Table of contents (47 papers)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Carcinogenicity of Polycyclic Aromatic Hydrocarbons: The Bay-Region Theory

    • D. M. Jerina, J. M. Sayer, D. R. Thakker, H. Yagi, W. Levin, A. W. Wood et al.
    Pages 1-12

  3. In Activation of ØX174 and SV 40 Viral DNA Replication by Diol Epoxide Derivatives of Carcinogenic Polycyclic Hydrocarbons

    • Ronald G. Harvey, Wen-Tah Hsu, George T. Chang, Samuel B. Weiss
    Pages 13-31

  4. Dihydrodiols and Diol-Epoxides in the Activation and Detoxification of Polycyclic Hydrocarbons

    • Peter Sims
    Pages 33-42

  5. Metabolically Generated Free Radicals from Many Types of Chemical Carcinogens and Binding of the Radicals with Nucleic Acid Bases

    • Chikayoshi Nagata, Masahiko Kodama, Teruyuki Kimura, Misako Aida
    Pages 43-54

  6. Nucleophilicity of DNA. Relation to Chemical Carcinogenesis.

    • Bernard Pullman, Alberte Pullman
    Pages 55-66

  7. An Analysis of the Reactivities of Epoxide Rings in Some Cyclic Hydrocarbons

    • Peter Politzer, Peter Trefonas III
    Pages 67-79

  8. Biological Effects of Specific Hydrocarbon-DNA Reactions

    • Peter Brookes, Robert F. Newbold
    Pages 81-90

  9. The Effect of Base Modification on Fidelity in Transcription

    • B. Singer
    Pages 91-102

  10. Modification of DNA by Carcinogenic Aromatic Amines In Vivo and In Vitro with Possible Promutagenic Consequences

    • E. Kriek
    Pages 103-111

  11. Biochemical Considerations of the Enzymology Associated with Quinone and Tetrol Formation During Benzo(A)Pyrene Metabolism

    • J. Capdevila, Y. Saeki, R. A. Prough, R. W. Estabrook
    Pages 113-124

  12. Stereochemical Aspects of Benzo[A]Pyrene Metabolism and Biochemical Individuality in Human Cells

    • Joseph Deutsch, Paul Okano, Harry V. Gelboin
    Pages 125-142

  13. Metabolic and Structural Requirements for the Carcinogenic Potencies of Unsubstituted and Methyl-Substituted Polycyclic Aromatic Hydrocarbons

    • Shen K. Yang, Ming W. Chou, Peter P. Fu
    Pages 143-156

  14. Formation and Inactivation of Dna-Binding Metabolites of Benzo(a)Pyrene Studied with Isolated Cells and Subcellular Fractions

    • Bengt Jernström, Thomas M. Guenthner, Sigrun Hesse, Sten Orrenius
    Pages 157-165

  15. Enzymic Control of Reactive Metabolites from Aromatic Carcinogens

    • F. Oesch, J. C. S. Clegg, R. Billings, K. L. Platt, H. R. Glatt
    Pages 167-177

  16. Aflatoxin-Dna Interactions: Qualitative, Quantitative and Kinetic Features in Relation to Carcinogenesis

    • Gerald N. Wogan, Robert G. Croy, John M. Essigmann, Richard A. Bennett
    Pages 179-191

  17. Structural Modifications and Specific Recognition by Antibodies of Carcinogenic Aromatic Amines Bound to DNA

    • M. P. Daune, G. de Murcia, A. M. Freund, R. P. P. Fuchs, M. C. Lang, M. Leng et al.
    Pages 193-205

  18. Immunological Detection and Quantification of DNA Components Structurally Modified by Alkylating Carcinogens (Ethylnitrosourea)

    • M. F. Rajewsky, R. Müller, J. Adamkiewicz, W. Drosdziok
    Pages 207-218

  19. Characteristics of Stages of Hepatocarcinogenesis

    • Henry C. Pitot
    Pages 219-233

  20. Mechanisms of Genetic Susceptibility to Cancer

    • D. G. Harnden
    Pages 235-244
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Keywords

Editors and Affiliations

  • Institut de Biologie Physico-Chimique (Fondation Edmond de Rothschild), Université Pierre et Marie Curie (Paris VI), Paris, France

    Bernard Pullman

  • The Johns Hopkins University, Baltimore, USA

    Paul O. P. Ts’o

  • National Cancer Institute, Bethesda, USA

    Harry Gelboin

Bibliographic Information

  • Book Title: Carcinogenesis: Fundamental Mechanisms and Environmental Effects

  • Book Subtitle: Proceedings of the Thirteenth Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, April 28 – May 2, 1980

  • Editors: Bernard Pullman, Paul O. P. Ts’o, Harry Gelboin

  • Series Title: Jerusalem Symposia

  • DOI: https://doi.org/10.1007/978-94-009-9104-0

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: D. Reidel Publishing Company, Dordrecht, Holland 1980

  • Hardcover ISBN: 978-90-277-1171-7Published: 31 October 1980

  • Softcover ISBN: 978-94-009-9106-4Published: 13 October 2011

  • eBook ISBN: 978-94-009-9104-0Published: 06 December 2012

  • Series ISSN: 0924-4875

  • Edition Number: 1

  • Number of Pages: IX, 592

  • Topics: Physical Chemistry

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