Regulation of Male Fertility

1. Front Matter

   Pages I-X

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2. Physiology of Male Reproduction

   1. Front Matter

      Pages 3-3

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   2. Hormonal Regulation of Testicular Function

      • P. Franchimont

      Pages 5-14

   3. Inhibin: New Gonadal Hormone

      • P. Franchimont, A. Demoulin, J. Verstraelen-Proyard, M. T. Hazee-Hagelstein, J. P. Bourguignon

      Pages 15-24

   4. Morphological Features of the Epididymis: Possible Significance in Male Contraception

      • T. D. Glover

      Pages 25-34

   5. Regulatory Physiology of Male Accessory Organs

      • E. S. E. Hafez, G. R. Cunningham

      Pages 35-39

   6. Methods for Evaluating Contraceptive Techniques

      • T. Z. Homonnai, F. G. Paz

      Pages 41-50

3. Hormonal Contraception

   1. Front Matter

      Pages 53-53

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   2. Inhibition of Male Reproductive Processes with an LH-RH Agonist

      • A. Corbin, F. J. Bex

      Pages 55-63

   3. LH-RH Agonists: Inhibition of Testicular Functions and Possible Clinical Applications

      • F. Labrie, A. Bélanger, G. Pelletier, C. Séguin, L. Cusan, P. A. Kelly et al.

      Pages 65-76

   4. Exogenous Androgens: Their Potential for Reversible Contraception

      • G. R. Cunningham, C. Huckins

      Pages 77-83

   5. Androgen-Progestin Combinations: Clinical Trials

      • J. Bain

      Pages 85-91

   6. Antiandrogens: Basic Concepts and Clinical Trials

      • F. Neumann, B. Schenck

      Pages 93-106

4. Biochemical Contraception

   1. Front Matter

      Pages 107-107

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   2. α-Chlorohydrin: Review of a Model Posttesticular Antifertility Agent

      • T. J. Lobl

      Pages 109-122

   3. The Contraceptive Effect of 6-Chloro-6-Deoxysugars in the Male

      • W. C. L. Ford

      Pages 123-126

   4. Interference with Spermatozoal Motility

      • N. Hofmann, R. Steiner

      Pages 127-133

   5. Interference with Spermatozoa Capacitation

      • A. Reyes, M. E. Chavarria, A. Rosado

      Pages 135-149

   6. Contraception by Acrosomal Proteinase Inhibitors

      • W.-B. Schill

      Pages 151-164

5. Surgical Contraception

   1. Front Matter

      Pages 167-167

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Many of the studies discussed in this book were addition to discussions of a variety of hormonal, presented at the First Pan American Congress of biochemical, immunological, physical, and me­ Andrology, which was held in Caracas, Venezuela, chanical approaches. It is our hope that the efforts in March 1979. An international group of in­ of the contributors will help to intensify research vestigators have contributed reviews designed to and development of improved methods for safely be informative to medical, graduate, and post­ regulating male fertility. graduate students, as well as clinicians and in­ vestigators working in the area of male reproduc­ G. R. CUNNINGHAM tion. Current physiological concepts that may W. B. SCHILL provide insight for new initiatives are examined in E. S. E. HAFEZ TABLE OF CONTENTS Preface v Contributors IX Foreword by C. SCHIRREN XI 1. PHYSIOLOGY OF MALE REPRODUCTION 1. Hormonal regulation of testicular function 5 P. FRANCHIMONT 2. Inhibin: new gonadal hormone 15 P. FRANCHIMONT, A. DEMOULIN, J. VERSTRAELEN-PROYARD, M. T. HAZEE-HAGELSTEIN, and J. P. BOURGUIGNON 3. Morphological features of the epididymis: possible significance in male contraception 25 T. D. GLOVER 4. Regulatory physiology of male accessory organs 35 E. S. E. HAFEZ and G. R. CUNNINGHAM 5. Methods for evaluating contraceptive techniques 41 T. Z. HOMONNAI and F. G. PAZ II. HORMONAL CONTRACEPTION 6. Inhibition of male reproductive processes with an LH-RH agonist 55 A. CORBIN and F. J. BEX 7.

• contraception
• fertility
• hormones
• regulation
• reproduction
• ultrasound

• Baylor College of Medicine, Veterans Administration Center, Houston, USA

  G. R. Cunningham

• Andrology Unit of the Department of Dermatology, University of Munich, Munich 2, West Germany

  W.-B. Schill

• Department of Gynecology-Obstetrics, Wayne State University School of Medicine, Medical Research Building, Detroit, USA

  E. S. E. Hafez

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