Hypertensive Cardiovascular Disease: Pathophysiology and Treatment

1. Front Matter

   Pages i-xvi

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2. Blood Pressure Control in Normotensive Subjects

   1. Role of the Kidney in Blood Pressure Regulation

      • Thomas G. Coleman, William R. Murphy, Thomas L. Smith, Karen A. Stanek

      Pages 3-17

   2. Role of Central Mechanisms in the Blood Pressure Regulation

      • Thomas Unger, Wolfgang Rascher, Rudolf E. Lang, Detlev Ganten

      Pages 18-33

   3. Arterial Baroreflexes in Normotensive and Hypertensive Man

      • Giuseppe Mancia, Alberto Zanchetti

      Pages 34-56

   4. Role of Catecholamines in Blood Pressure Regulation

      • A. Distler

      Pages 57-70

   5. Role of the Renin-Angiotensin System and Prostaglandins in Blood Pressure Regulation and Sodium Homeostasis

      • Rainer Dusing, James B. Lee

      Pages 71-85

   6. Role of Kallikrein in Blood Pressure Regulation

      • Klaus O. Stumpe, Axel Overlack

      Pages 86-103

   7. The Lability of Blood Pressure

      • John S. Floras, Peter Sleight

      Pages 104-117

3. Experimental Hypertension

   1. Pathophysiology of Hypertension in Genetically Hypertensive Rats — Environmental Modification and Prevention

      • Yukio Yamori

      Pages 118-131

   2. The Pathophysiology of Hypertension: Contributions of Experimental Pathophysiology

      • J. Carlos Romero, William H. Beierwaltes, Peter C. Houck

      Pages 132-153

4. Pathogenesis of Primary Hypertension

   1. Role of Changes in Na+ Transport in Cell Membranes in the Pathogenesis of Primary Hypertension

      • Philippe Meyer

      Pages 154-163

   2. Pathophysiology of Primary Hypertension: Role of Adrenoceptors in the Transformation from an Early High Cardiac Output into a Later High Arteriolar Resistance Phase

      • Fritz R. Bühler

      Pages 164-205

   3. Genetics in Human Hypertension

      • John M. Ledingham

      Pages 206-216

   4. Psychophysiologic Evidence for the Role of the Nervous System in Hypertension

      • Stevo Julius

      Pages 217-230

   5. Interaction between Functional and Structural Elements in Primary Hypertension

      • Björn Folkow, Margareta Hallbäck-Nordlander

      Pages 231-248

   6. Role of the Kidney in the Pathogenesis of Primary Hypertension

      • Giuseppe Bianchi

      Pages 249-263

   7. Role of Sodium in the Pathogenesis of Idiopathic Hypertension

      • Frederic C. Bartter

      Pages 264-276

   8. Role of Obesity in the Pathogenesis of Primary Hypertension

      • H. E. Eliahou

      Pages 277-289

   9. Role of Catecholamines in the Pathogenesis of Primary Hypertension

      • P. W. de Leeuw, W. H. Birkenhäger

      Pages 290-303

   10. Role of Renin in the Control of the Circulation in Hypertensive Disease and in Heart Failure

       • Edgar Haber

       Pages 304-325

Hypertension is a major world-wide health problem. With high blood pressure there is a greater risk of stroke, heart attack, heart failure, kidney disease and renal failure. Far too few people realize what the risks are and what can be done to prevent these risks even in the countries where pro­ grams in hypertension research are active and the full significance of hyper­ tension is best understood. Some studies of the known hypertensive popu­ lation indicate that one-half or less are receiving adequate treatment, and, of those on therapy, only half have their high blood pressure satisfactorily controlled. These realizations emphasize the need to inform all segments of society throughout the world on the importance of detection and control of high blood pressure. The great incidence of hypertension makes it of para­ mount importance that all practicing physicians have available the latest information on diagnosis and treatment of hypertensive cardiovascular dis­ ease. This treatise on hypertension arrives at a time when there is an increasing recognition the world over of the importance of detecting and treating high blood pressure. The book has been edited by Dr. A. Amery and his asso­ ciates in the University of Leuven. Professor Amery is one of the leaders in the field of hypertension and serves on the Council of the International Society of Hypertension.

• anesthesia
• blood pressure
• cardiovascular
• circulation
• genetics
• heart
• hemodynamics
• hypertension
• vascular disease

• Hypertension and Cardiovascular Rehabilitation Unit, Department of Pathophysiology, University of Leuven, K.U. Leuven, Leuven, Belgium

  A. Amery, R. Fagard, P. Lijnen, J. Staessen

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