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  • Book
  • © 1984

LHRH and Its Analogs

Contraceptive and Therapeutic Applications

Editors:

  1. B. H. Vickery
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  2. J. J. Nestor
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  3. E. S. E. Hafez
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Part of the book series: Advances in Reproductive Health Care (ARHE, volume 1)

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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xxix
    PDF

  2. Chemistry and Basic Reproductive Properties

    1. Front Matter

      Pages 1-1
      PDF

    2. Development of agonistic LHRH analogs

      • J. J. Nestor Jr.
      Pages 3-10

    3. LHRH analogs as antiovulatory agents

      • J. Rivier, C. Rivier, M. Perrin, J. Porter, W. Vale
      Pages 11-22

    4. LHRH agonists and antagonists containing very hydrophobic amino acids

      • J. J. Nestor Jr., T. L. Ho, R. Tahilramani, B. L. Horner, R. A. Simpson, G. H. Jones et al.
      Pages 23-33

  3. Reproductive Physiology and Pharmacology in Laboratory Animals

    1. Front Matter

      Pages 47-47
      PDF

    2. Biological assays utilized to characterize LHRH and its analogs

      • D. W. Hahn, J. L. McGuire, W. Vale, J. Rivier
      Pages 49-60

    4. Male fertility control with an LHRH agonist: primate studies

      • F. Bint Akhtar, E. J. Wickings, E. Nieschlag
      Pages 77-90

    5. LHRH agonists for control of female fertility: primate studies

      • B. H. Vickery, G. I. McRae
      Pages 91-106

    6. LHRH antagonists in rhesus and cynomolgus monkeys

      • R. H. Asch, J. P. Balmaceda, M. Borghi
      Pages 107-123

    7. LHRH antagonists in females

      • M. V. Nekola, D. H. Coy
      Pages 125-136

    8. Biological activity of a highly potent LHRH antagonist

      • G. I. McRae, B. H. Vickery, J. J. Nestor Jr., W. J. Bremner, T. M. Badger
      Pages 137-151

    9. LHRH antagonists for male contraception

      • D. Heber, R. S. Swerdloff
      Pages 153-160

  4. Extrahypophysial Parameters

    1. Front Matter

      Pages 161-161
      PDF

    2. Direct antigonadal actions of LHRH

      • P. B. C. Jones, A. J. W. Hsueh
      Pages 163-179

    3. Direct gonadal stimulation with LHRH

      • H. M. Fraser, R. M. Sharpe, R. M. Popkin
      Pages 181-195

    4. Antisteroidal actions of LHRH agonists

      • K. Sundaram, C. W. Bardin
      Pages 197-204

  5. Contraception in Women

    1. Front Matter

      Pages 205-205
      PDF
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About this book

A. CORBIN Investigations on LHRH and its analogs have just completed their first decade. We have witnessed a veritable explosion of chemical, physiologic and pharmacologic data on this hypothalamic peptide and the approximately 1500 agonist and antagonist analogs that have been synthesized. In order to track this expanding field, I was asked to organize an international symposium on basic and clinical aspects of LHRH analogs as part of the Reproductive Health Care: CDS Symposium held in Maui, Hawaii, in October 1982. This meeting brought together a number of the leading investigators in the field. Much new state-of-the-art information was presented which I and my colleagues felt deserved a wider audience. Drs Vickery, Nestor, and Hafez consented to undertake this task. Upon review of the literature, it was apparent that there was no recent text which fully covered the breadth of developments in the field. Accordingly, the editors decided to use the symposium as a nucleus on which to build a singular, comprehensive state-of-the-art analysis of this rapidly growing discipline, and the application of such knowledge to reproductive medicine. As exemplified by the various areas of expertise provided by the individual contributors, it becomes obvious that the scope of the subject matter, while relating solely to a well-defined chemical class (LHRH analogs) and a circumscribed physiologic and pharmacologic entity (reproduction), has expanded enormously.
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Keywords

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Bibliographic Information

  • Book Title: LHRH and Its Analogs

  • Book Subtitle: Contraceptive and Therapeutic Applications

  • Editors: B. H. Vickery, J. J. Nestor, E. S. E. Hafez

  • Series Title: Advances in Reproductive Health Care

  • DOI: https://doi.org/10.1007/978-94-009-5588-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1984

  • Softcover ISBN: 978-94-010-8963-0Published: 19 January 2012

  • eBook ISBN: 978-94-009-5588-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 500

  • Topics: Gynecology, Diabetes

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Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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