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Physiology of the Fetal and Neonatal Lung

Proceedings of the International Symposium on Physiology and Pathophysiology of the Fetal and Neonatal Lung, held in Brussels, June 6–8, 1985

  • Conference proceedings
  • © 1987

Overview

Editors:
  1. D. V. Walters

    1. Department of Paediatrics, University College Hospital Medical School, The Rayne Institute, London, UK

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  2. L. B. Strang

    1. Department of Paediatrics, University College Hospital Medical School, The Rayne Institute, London, UK

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  3. F. Geubelle

    1. Clinic des Maladies de l’Enfance, Université de Liege, Belgium

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Table of contents (20 papers)

  1. Front Matter

    Pages i-xiii
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  2. Lung Embryogenesis and Differentiation

    • L. Marin
    Pages 1-15

  3. Differentiation of the Pulmonary Epithelium

    • B. T. Smith, M. Post, J. Floros
    Pages 17-24

  4. Factors Affecting Fetal Lung Growth

    • J. S. Wigglesworth
    Pages 25-37

  5. Postnatal Lung Development and Modulation of Lung Growth

    • P. H. Burri
    Pages 39-59

  6. The Secretion and Absorption of Fetal Lung Liquid

    • D. V. Walters, C. A. Ramsden
    Pages 61-75

  7. Development of Epithelial Ion Transport in Fetal and Neonatal Airways

    • J. T. Gatzy, C. U. Cotton, R. C. Boucher, M. R. Knowles, C. W. Gowen Jr.
    Pages 77-89

  8. Analysis of Ion and Fluid Transport Across a Vertebrate Pulmonary Epithelium Studied In Vitro

    • M. R. Ward, C. A. R. Boyd
    Pages 91-105

  9. The Maturation of the Control of Respiration in Infancy

    • P. J. Fleming, M. R. Levine, A. M. Long, J. Cleave
    Pages 107-127

  10. Establishment of the End-Expiratory Level (FRC) in Newborn Mammals

    • J. P. Mortola
    Pages 129-138

  11. Postnatal Development of Lung Function

    • Cl. Gaultier
    Pages 139-154

  12. Alveolar Ventilation in Newborns and its Postnatal Development

    • D. Lagneaux, F. Geubelle
    Pages 155-167

  13. Some Relationships Among Structure, Composition, and Functional Characteristics of Lung Surfactant

    • J. A. Clements
    Pages 169-182

  14. Aspects of Surfactant Metabolism in the Adult and Perinatal Lung

    • L. M. G. Van Golde, R. Burkhardt, A. C. J. De Vries, J. J. Batenburg
    Pages 183-196

  15. myo-Inositol and Perinatal Development of Surfactant

    • M. Hallman
    Pages 197-208

  16. Absorption of Fetal Lung Liquid and Exogenous Surfactant in Premature Lambs

    • E. A. Egan, M. S. Kwong, R. H. Notter
    Pages 209-223

  17. Surfactant Inhibitory Plasma-Derived Proteins

    • W. Seeger, G. Stöhr, H. Neuhof
    Pages 225-240

  18. Surfactant Replacement: Theory and Practice

    • B. Robertson
    Pages 241-254

  19. The Cambridge Experience of Artificial Surfactant

    • C. J. Morley
    Pages 255-274

  20. Surfactant Supplementation: Toronto Trial

    • G. Enhörning
    Pages 275-285
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Keywords

About this book

L. B. STRANG The past 25 years have seen a remarkable growth in our knowledge of lung development in its structural, physiological and biochemical dimensions. Much of the impetus for research leading to new knowledge has derived from the perception that many respiratory disorders in the newborn infant are due to defective development or maladaption of some component or components of the respiratory system. Thus, to cite one example, surfac­ tant deficiency is clearly seen to be the cause of atelectasis in hyaline mem­ brane disease; and to cite another, it is widely accepted that the mechanisms controlling patency of the ductus arteriosus and pulmonary vascular resistance also determine the right-to-Ieft or left-to-right shunting frequently observed in the course of neonatal respiratory disorders. There are, however, areas of physiological knowledge - such as those relating to respiratory control and to liquid formation and absorption - which are clearly of great relevance to lung adaptation at birth but where it has not yet proved possible to link a specific clinical state to the malfunction of a particular mechanism. In planning this symposium an attempt was made to organize the material in an orderly manner, starting with the embryonic and fetal stages of growth and development, continuing with respiratory control and the role of surfactant in lung aeration at birth, and ending with the treatment of neonatal respiratory disorders.

Editors and Affiliations

  • Department of Paediatrics, University College Hospital Medical School, The Rayne Institute, London, UK

    D. V. Walters, L. B. Strang

  • Clinic des Maladies de l’Enfance, Université de Liege, Belgium

    F. Geubelle

Bibliographic Information

  • Book Title: Physiology of the Fetal and Neonatal Lung

  • Book Subtitle: Proceedings of the International Symposium on Physiology and Pathophysiology of the Fetal and Neonatal Lung, held in Brussels, June 6–8, 1985

  • Editors: D. V. Walters, L. B. Strang, F. Geubelle

  • DOI: https://doi.org/10.1007/978-94-009-4155-7

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1987

  • Softcover ISBN: 978-94-010-8344-7Published: 22 February 2012

  • eBook ISBN: 978-94-009-4155-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 300

  • Topics: Pediatrics

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