Ethopharmacology of Agonistic Behaviour in Animals and Humans

1. Front Matter

   Pages I-X

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2. Experimental Models of Social and Aggressive Behaviour

   1. Frustration, Aggression and Drugs

      • Robert Dantzer

      Pages 1-13

   2. Pharmacological Aspects of Social Cooperation

      • Barry D. Berger, Richard Schuster

      Pages 14-32

   3. Ethopharmacology of Hypothalamic Aggression in the Rat

      • M. R. Kruk, A. M. Van der Poel, J. H. C. M. Lammers, Th. Hagg, A. M. D. M. De Hey, S. Oostwegel

      Pages 33-45

3. Flight, Defence and Adaptive Strategies

   1. Ethopharmacology of Flight Behaviour

      • A. Keith Dixon, Hans-Peter Kaesermann

      Pages 46-79

   2. Situational-Dependence and Differential Mediation of Analgesic Reactions to Conspecific Attack in Mice

      • R. John Rodgers, Jill I. Randall

      Pages 80-93

4. Ethopharmacological Studies of Aggression in Mice

   1. Studies Contrasting Drug Effects on Reproduction Induced Agonistic Behaviour in Male and Female Mice

      • H. Yoshimura

      Pages 94-109

   2. The Utility of Ethological Assessments of Murine Agonistic Interactions in Behavioural Teratology: The Foetal Alcohol Syndrome

      • Paul F. Brain, Jamaan S. Ajarem, Vesselin V. Petkov

      Pages 110-121

   3. Ethopharmacological and Neuropharmacological Analyses of Agonistic Behaviour

      • Vladimir P. Poshivalov

      Pages 122-131

5. Ethopharmacological Studies of Aggression in Rats

   1. Psychopharmacology of Social Play

      • Jaak Panksepp, Larry Normansell, James F. Cox, Loring J. Crepeau, David S. Sacks

      Pages 132-144

   2. The Relationship between Ethanol and Aggression: Studies Using Ethological Models

      • Robert J. Blanchard, D. Caroline Blanchard

      Pages 145-161

   3. Serotonergic Modulation of Agonistic Behaviour

      • Berend Olivier, Jan Mos, Jan van der Heyden, Jacques Schipper, Martin Tulp, Bas Berkelmans et al.

      Pages 162-186

   4. Pro-Aggressive Actions of Benzodiazepines

      • Jan Mos, Berend Olivier

      Pages 187-206

6. Ethopharmacological Studies of Aggression and Dominance in Monkeys

   1. Serotonin, Social Behaviour, and Aggression in Vervet Monkeys

      • Michael T. McGuire, Michael J. Raleigh

      Pages 207-222

   2. Alcohol Effects on the Aggressive Behaviour of Squirrel Monkeys and Mice are Modulated by Testosterone

      • James T. Winslow, Joseph F. DeBold, Klaus A. Miczek

      Pages 223-244

7. Psychopharamacological Studies of Human Aggression

   1. Psychopharmacology of Human Aggression: Laboratory Studies

      • Don R. Cherek, Joel L. Steinberg

      Pages 245-256

   2. Psychopharmacology of Aggression in Humans

      • Michael H. Sheard

      Pages 257-266

8. Back Matter

   Pages 267-270

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. Aggression research is in a rapid state of development. The accelerating knowledge of neurotransmitter systems in the brain, their behavioural functions and the development of drugs which may specifically affect systems related to attack and defence is fruitfully combined with studies in which basic ethological observation and quantification techniques are used more routinely. Moreover, much of the experimental effort has finally applied some order to the initial chaos which afflicted the various experimental aggression models used in pharmacological, physiological and ethological research. This highly desirable trend not only leads to a better understanding of the phenomena studied and the terminologies employed, but it increases our awareness of the multiplicity of factors that are important, making it difficult to allow over hasty and simple generalizations. This book is a compilation of studies presented at the International Society for Research on Aggression meeting in Chicago 1986, in which leading investigators were invited to cover aspects of ethopharmacological aggression research in a wide variety of species, including studies on humans. The level to which ethological techniques have been incorporated into the various areas of research differs, as well as the knowledge and understanding of the neurotransmitter and experimental drug action on brain functioning in mammalian species. This naturally results in data which are not always easy to compare or to extrapolate between species but useful indicators are starting to emerge.

• behavior
• drug
• ethanol
• psychopharmacology
• research
• serotonin

• Department of Pharmacology, Duphar B. V., Weesp, The Netherlands

  B. Olivier, J. Mos

• Department of Zoology, University College of Swansea, Swansea, Wales, UK

  P. F. Brain

Policies and ethics