The Comparative Physiology of Regulatory Peptides

1. Front Matter

   Pages i-x

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2. Distribution and function of regulatory peptides

   1. Front Matter

      Pages 1-1

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   2. Atrial natriuretic peptides — localization, structure, function and phylogeny

      • Manfred Reinecke

      Pages 3-33

   3. Bombesin

      • Steven R. Vigna, Michael C. Thorndyke

      Pages 34-60

   4. Gastrin/cholecystokinin-related peptides — comparative aspects

      • Ann-Cathrine Jönsson

      Pages 61-86

   5. Neurotensin and related peptides

      • Robert E. Carraway, Manfred Reinecke

      Pages 87-111

   6. Opioid peptides — comparative peripheral mechanisms

      • George B. Stefano

      Pages 112-129

   7. Substance P and other tachykinins

      • Jörgen Jensen

      Pages 130-149

   8. Vasoactive intestinal peptide

      • Rod Dimaline

      Pages 150-173

   9. Pancreatic peptides

      • Erika M. Plisetskaya

      Pages 174-202

   10. Peptides in invertebrates

       • Michael C. Thorndyke

       Pages 203-228

3. Integrated physiological functions

   1. Front Matter

      Pages 229-229

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   2. Gut motility

      • Susanne Holmgren

      Pages 231-255

   3. Gut secretion

      • Ann-Cathrine Jönsson, Susanne Holmgren

      Pages 256-271

   4. The cardiovascular system

      • Judy L. Morris

      Pages 272-307

   5. Co-existence and co-function

      • Ian L. Gibbins

      Pages 308-343

   6. Biosynthesis of regulatory peptides — evolutionary aspects

      • J. Michael Conlon

      Pages 344-369

4. Back Matter

   Pages 370-380

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Strictly speaking, the term regulatory peptides may include any peptide which has a regulatory function in any organism. In recent years, how­ ever, the term has come to mean those originally classified as brain-gut peptides. The peptides initially defined as those belonging to the brain­ gut axis had a dual location in neurones of the brain and endocrine cells of the gut. We now include a number of neuropeptides found in the autonomic nervous system of the gut, the cardiovascular system and other systems. To many scientists comparative physiology means comparison of the mechanisms of certain functions in the rat, the guinea-pig, the cat and maybe some other mammal. If the philosophy is that man is the centre of the universe and other mammals can be used as 'models' of man, this may well be the most useful way to study the functions of the human being, without actually chopping somebody up. However, with a some­ what wider perspective on life, it is easy to see the importance of a full understanding of the function of all living organisms, in its own right as well as a link in the evolution towards individuals able to survive and reproduce in very different environments. The importance of com­ parative studies in all living organisms cannot be emphasized too much. It has been the ambition with this book to treat all animals as equally important.

• Universe
• animals
• biosynthesis
• brain
• cells
• environment
• evolution
• invertebrates
• nervous system
• peptide
• phylogeny
• physiology
• structure
• synthesis
• system

• Department of Zoophysiology, University of Göteborg, Sweden

  Susanne Holmgren

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