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PTCA An Investigational Tool and a Non-Operative Treatment of Acute Ischemia

  • Book
  • © 1990

Overview

Editors:
  1. Patrick W. Serruys

    1. Cardiac Catheterization Laboratory, Thorax Center, Erasmus University, Rotterdam, The Netherlands

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  2. Rüdiger Simon

    1. Department of Cardiology, University Hospital, Kiel, Germany

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    You can also search for this editor in PubMed   Google Scholar

  3. Kevin J. Beatt

    1. Academic Unit of Cardiovascular Medicine, Charing Cross and Westminster Hospital, London, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 101)

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xix
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  2. An investigational tool

    1. Front Matter

      Pages 1-1
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    2. From in-vitro to in-vivo model

      1. Myocardial ischemia
        • Guy R. Heyndrickx, Williamas Wijns, Stephen F. Vatner
        Pages 3-22
      2. Early changes in wall thickness and epicardial wall motion during percutaneous transluminal coronary angioplasty in man
        • Patrick W. Serruys, Brian Jaski, Federico Piscione, Folkert Ten Kate, Pim De Feyter, Marcel Van Den Brand et al.
        Pages 23-35
      3. Early mechanical changes associated with coronary artery occlusion
        • Mario Marzilli
        Pages 37-42

    4. Role of collaterals during PTCA

      1. Collaterals and coronary wedge pressure
        • B. De Bruyne, B. Meier
        Pages 75-91

    5. Coronary flow and flow reserve

      1. Intracoronary blood flow velocity, reactive hyperemia and coronary blood flow reserve during and following PTCA
        • Patrick W. Serruys, Felix Zijlstra, Hans H. C. Reiber, Kevin Beatt, G. J. Laarman, Jos Roelandt et al.
        Pages 93-120

    6. Myocardial metabolism

      1. Loss of hydrogen and potassium ions after short periods of myocardial ischaemia in man
        • P. A. Poole-Wilson
        Pages 121-126
      2. Myocardial release of hypoxanthine and lactate during coronary angioplasty
        • Patrick W. Serruys, Federico Piscione, William Wijns, Johan A. J. Hegge, Eef Harmsen, Marcel Van Den Brand et al.
        Pages 127-142
      3. Myocardial release of hypoxanthine and urate during angioplasty
        • Jan Willem De Jong, Tom Huizer, J. Arly Nelson, Wlodzimierz Czarnecki, Johannes J. R. M. Bonnier, Patrick W. Serruys
        Pages 143-150
      4. Regional myocardial nitrogen-13-glutamate uptake following successful coronary angioplasty
        • Harald Tillmanns, Rainer Zimmermann, Wolfram H. Knapp, Frantisek Helus, Peter Georgi, Bernhard Rauch et al.
        Pages 151-154

    7. Myocardial function

      1. Left atrial function in acute transient ischemia of the left ventricle
        • Milan Grbic, Ulrich Sigwart
        Pages 155-165
      2. Left ventricular filling during acute ischemia
        • M. Grbic, U. Sigwart
        Pages 167-174
      3. Left ventricular function during acute coronary artery balloon occlusion in humans
        • Michel E. Bertrand, Jean M. Lablanche, Jean L. Fourrier, Antoine Gommeaux, Israel Mirsky
        Pages 175-191
      4. Use of intravenous DSA in the assessment of LV performance during PTCA
        • Michael S. Norell, Raphael Balcon
        Pages 193-205
      5. Two dimensional echocardiography during PTCA
        • Cees A. Visser, Jacques J. Koolen, George K. David, Arend J. Dunning
        Pages 207-216
      6. Doppler echocardiographic assessment of left ventricular function during PTCA
        • Anthony C. Pearson, Arthur J. Labovitz, Morton Kern, Michel Vandormael
        Pages 217-231
      7. Ejection filling and diastasis during transluminal occlusion in man
        • Patrick W. Serruys, Federico Piscione, William Wijns, Cees Slager, Pim De Feyter, Marcel Van Den Brand et al.
        Pages 233-266
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Keywords

About this book

Obstruction of coronary blood flow and the resultant consequences are the center stage pathophysiologic events in cardiology today. The speculations of Jenner, Burns, Heberdin, McKenzie, Prinzmetal and many others had until now been left to observations of isolated tissue and intact animal experimentation. Only with the advent of Gruentzig's technique, which allowed us to 'work safely inside the coronary arteries' are we able to observe the effects of coronary occlusion in living conscious man. PTCA provides not only a therapeutic modality for non-operatively opening coronary obstructions, but has also provided the best model for studying the effects of acute ischemia on the heart. The procedure also lead the way to all other interventional cardiology developments, including modern thrombolysis in the setting of acute myocardial infarction. In his previous works, Serruys has examined how PTCA can serve as a model for studying acute ischemia. In this book, he and his co-authors discuss the effects of balloon-induced ischemia on the electrocardiographic changes, coronary blood flow dynamics, cardiac muscle metabolism and left ventricular function, as well as measures to counter these effects and provide for reperfusion in unstable angina and acute myocardial infarction. Technology has expanded the 'eyes' of the observer of these events. The authors use many techniques including ECG recording from surface, endocardium, and intracoronary electrodes; angiographic assessment of coronary flow pattern using digital techniques, as well as doppler flow measurements; biochemical assessment of metabolic products stimulated by ischemia; and digital angiographic and echo doppler assessment of left ventricular function.

Reviews

`... durch die hervorragende Aufmachung and übersichtliche Gestaltung. Für jeden Kardiologen und Herzchirurgen ein unentbehrliches Werk, das den neuesten Stand dieser Behandlungsmethode aufzeigt.'
Herz/Kreislauf, 23/1, 1991

Editors and Affiliations

  • Cardiac Catheterization Laboratory, Thorax Center, Erasmus University, Rotterdam, The Netherlands

    Patrick W. Serruys

  • Department of Cardiology, University Hospital, Kiel, Germany

    Rüdiger Simon

  • Academic Unit of Cardiovascular Medicine, Charing Cross and Westminster Hospital, London, UK

    Kevin J. Beatt

Bibliographic Information

  • Book Title: PTCA An Investigational Tool and a Non-Operative Treatment of Acute Ischemia

  • Editors: Patrick W. Serruys, Rüdiger Simon, Kevin J. Beatt

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-94-009-0453-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1990

  • Softcover ISBN: 978-94-010-6688-4Published: 20 September 2011

  • eBook ISBN: 978-94-009-0453-8Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: 400

  • Topics: Cardiology

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