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  • Book
  • © 2014

Lipid Hydroperoxide-Derived Modification of Biomolecules

Editors:

  1. Yoji Kato

    1. School of Human Science & Environment, University of Hyogo, Himeji, Japan

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  • Provides novel aspects of the nature of lipid hydroperoxides
  • Wide range information from chemistry to pathology related to lipid hydroperoxide
  • Includes methodology of oxidative stress biomarker analyses

Part of the book series: Subcellular Biochemistry (SCBI, volume 77)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii
    PDF

  2. Lipid Peroxidation and Small Molecule Adducts

    1. Front Matter

      Pages 1-1
      PDF

    2. Lipid Hydroperoxides as a Source of Singlet Molecular Oxygen

      • Sayuri Miyamoto, Paolo Di Mascio
      Pages 3-20

    5. Amide-Type Adduct of Dopamine – Plausible Cause of Parkinson Diseases

      • Xuebo Liu, Naruomi Yamada, Toshihiko Osawa
      Pages 49-60

    6. Determination of HEL (Hexanoyl-Lysine Adduct): A Novel Biomarker for Omega-6 PUFA Oxidation

      • Kazuo Sakai, Satoko Kino, Aino Masuda, Masao Takeuchi, Tairin Ochi, Josko Osredkar et al.
      Pages 61-72

  3. Pathophysiological Consequences

    1. Front Matter

      Pages 93-93
      PDF

    2. Amide-Adducts in Atherosclerosis

      • Michitaka Naito
      Pages 95-102

    3. Oxidative Modification of Lipoproteins

      • Hirofumi Arai
      Pages 103-114

    5. Role of Lipid Peroxide in the Neurodegenerative Disorders

      • Wakako Maruyama, Masayo Shaomoto-Nagai, Yoji Kato, Shinsuke Hisaka, Toshihiko Osawa, Makoto Naoi
      Pages 127-136

    6. Lipid Hydroperoxide-Derived Modification of Proteins in Gastrointestinal Tract

      • Yuji Naito, Tomohisa Takagi, Osamu Handa, Toshikazu Yoshikawa
      Pages 137-148

  4. Applications for Diagnosis and Development of Functional Food

    1. Front Matter

      Pages 149-149
      PDF

    2. Low-Cost and Easy-to-Use “on-Chip ELISA” for Developing Health-Promoting Foods

      • Fumihiko Hoshino, Osamu Watanabe, Xiaohong Wu, Yosuke Takimoto, Toshihiko Osawa
      Pages 151-161

    4. Potential Role of Oxidative Protein Modification in Energy Metabolism in Exercise

      • Wataru Aoi, Yuji Naito, Toshikazu Yoshikawa
      Pages 175-187
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About this book

Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is formed in an initial step of lipid peroxidation. Lipid hydroperoxide is also known as a potential source of singlet oxygen. Harmful aldehydes are formed when the lipid hydroperoxide is degraded. The formed aldehyde has high reactivity against thiol or amine moieties. Therefore, it could act as a signaling molecule, which might induce the changing of gears inside a cell. Recent studies have shown that lipid hydroperoxide or a slightly modified product of the lipid hydroperoxide reacts with biomolecules such as proteins and aminophospholipids, which leads to formation of amide-type adducts. Amide-type adducts could be one of markers for oxidative stress and could also be an important player in some diseases. In this book, the chemistry and biochemistry of lipid hydroperoxide along with their conjugates with biomolecules are described.
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Keywords

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Editors and Affiliations

  • School of Human Science & Environment, University of Hyogo, Himeji, Japan

    Yoji Kato

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Bibliographic Information

  • Book Title: Lipid Hydroperoxide-Derived Modification of Biomolecules

  • Editors: Yoji Kato

  • Series Title: Subcellular Biochemistry

  • DOI: https://doi.org/10.1007/978-94-007-7920-4

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2014

  • Hardcover ISBN: 978-94-007-7919-8Published: 15 January 2014

  • Softcover ISBN: 978-94-024-0296-4Published: 17 September 2016

  • eBook ISBN: 978-94-007-7920-4Published: 28 December 2013

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 1

  • Number of Pages: VIII, 202

  • Number of Illustrations: 51 b/w illustrations, 27 illustrations in colour

  • Topics: Cancer Research, Posttranslational Modification, Food Science

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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