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Lipid Hydroperoxide-Derived Modification of Biomolecules

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  • © 2014
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Overview

Editors:
  1. Yoji Kato

    1. School of Human Science & Environment, University of Hyogo, Himeji, Japan

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  • Provides novel aspects of the nature of lipid hydroperoxides
  • Wide range information from chemistry to pathology related to lipid hydroperoxide
  • Includes methodology of oxidative stress biomarker analyses

Part of the book series: Subcellular Biochemistry (SCBI, volume 77)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii
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  2. Lipid Peroxidation and Small Molecule Adducts

    1. Front Matter

      Pages 1-1
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    2. Lipid Hydroperoxides as a Source of Singlet Molecular Oxygen

      • Sayuri Miyamoto, Paolo Di Mascio
      Pages 3-20
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    3. The Formation of Lipid Hydroperoxide-Derived Amide-Type Lysine Adducts on Proteins: A Review of Current Knowledge

      • Yoji Kato
      Pages 21-39
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    4. Lipid Hydroperoxide-Derived Adduction to Amino-Phospholipid in Biomembrane

      • Shinsuke Hisaka, Toshihiko Osawa
      Pages 41-48
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    5. Amide-Type Adduct of Dopamine – Plausible Cause of Parkinson Diseases

      • Xuebo Liu, Naruomi Yamada, Toshihiko Osawa
      Pages 49-60
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    6. Determination of HEL (Hexanoyl-Lysine Adduct): A Novel Biomarker for Omega-6 PUFA Oxidation

      • Kazuo Sakai, Satoko Kino, Aino Masuda, Masao Takeuchi, Tairin Ochi, Josko Osredkar et al.
      Pages 61-72
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    7. Hexanoyl-Lysine as a Deterioration Marker for Rice During Storage

      • Ken-ichiro Minato
      Pages 73-82
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    8. Cholesterol Hydroperoxides and Their Degradation Mechanism

      • Junji Terao
      Pages 83-91
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  3. Pathophysiological Consequences

    1. Front Matter

      Pages 93-93
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    2. Amide-Adducts in Atherosclerosis

      • Michitaka Naito
      Pages 95-102
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    3. Oxidative Modification of Lipoproteins

      • Hirofumi Arai
      Pages 103-114
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    4. Immunochemical Detection of Lipid Hydroperoxide- and Aldehyde-Modified Proteins in Diseases

      • Akihiko Sugiyama, Jing Sun
      Pages 115-125
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    5. Role of Lipid Peroxide in the Neurodegenerative Disorders

      • Wakako Maruyama, Masayo Shaomoto-Nagai, Yoji Kato, Shinsuke Hisaka, Toshihiko Osawa, Makoto Naoi
      Pages 127-136
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    6. Lipid Hydroperoxide-Derived Modification of Proteins in Gastrointestinal Tract

      • Yuji Naito, Tomohisa Takagi, Osamu Handa, Toshikazu Yoshikawa
      Pages 137-148
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  4. Applications for Diagnosis and Development of Functional Food

    1. Front Matter

      Pages 149-149
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    2. Low-Cost and Easy-to-Use “on-Chip ELISA” for Developing Health-Promoting Foods

      • Fumihiko Hoshino, Osamu Watanabe, Xiaohong Wu, Yosuke Takimoto, Toshihiko Osawa
      Pages 151-161
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    3. Hexanoyl-Lysine as an Oxidative-Injured Marker – Application of Development of Functional Food

      • Ken-ichiro Minato, Yoshiaki Miyake
      Pages 163-174
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    4. Potential Role of Oxidative Protein Modification in Energy Metabolism in Exercise

      • Wataru Aoi, Yuji Naito, Toshikazu Yoshikawa
      Pages 175-187
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    5. Suppressive Effects of Cacao Polyphenols on the Development of Atherosclerosis in Apolipoprotein E-Deficient Mice

      • Midori Natsume, Seigo Baba
      Pages 189-198
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Keywords

About this book

Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is formed in an initial step of lipid peroxidation. Lipid hydroperoxide is also known as a potential source of singlet oxygen. Harmful aldehydes are formed when the lipid hydroperoxide is degraded. The formed aldehyde has high reactivity against thiol or amine moieties. Therefore, it could act as a signaling molecule, which might induce the changing of gears inside a cell. Recent studies have shown that lipid hydroperoxide or a slightly modified product of the lipid hydroperoxide reacts with biomolecules such as proteins and aminophospholipids, which leads to formation of amide-type adducts. Amide-type adducts could be one of markers for oxidative stress and could also be an important player in some diseases. In this book, the chemistry and biochemistry of lipid hydroperoxide along with their conjugates with biomolecules are described.

Editors and Affiliations

  • School of Human Science & Environment, University of Hyogo, Himeji, Japan

    Yoji Kato

Bibliographic Information

  • Book Title: Lipid Hydroperoxide-Derived Modification of Biomolecules

  • Editors: Yoji Kato

  • Series Title: Subcellular Biochemistry

  • DOI: https://doi.org/10.1007/978-94-007-7920-4

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2014

  • Hardcover ISBN: 978-94-007-7919-8Published: 15 January 2014

  • Softcover ISBN: 978-94-024-0296-4Published: 17 September 2016

  • eBook ISBN: 978-94-007-7920-4Published: 28 December 2013

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 1

  • Number of Pages: VIII, 202

  • Number of Illustrations: 51 b/w illustrations, 27 illustrations in colour

  • Topics: Cancer Research, Posttranslational Modification, Food Science

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