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Experimental Metastasis: Modeling and Analysis

  • Book
  • © 2013

Overview

Editors:
  1. Anastasia Malek

    1. Oncoendocrinology, Petrov Institute of Oncology, St Petersburg, Russia

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  • Structure of the book is based on anatomical areas of cancer dissemination that has clinical relevance
  • Any chapter is written/supervised by leading researcher in specific area of metastasis research
  • The book is focused on experimental approach of metastatic cancer research: any chapter contains supportive theoretical information and detailed description of relevant laboratory procedures
  • The book is supplemented by informative illustrations, schemes and tables
  • Extensive lists of references for any chapter provides with possibility of effective deep study
  • Includes supplementary material: sn.pub/extras

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-viii
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  2. Introduction: Experimental Metastasis

    • Anastasia Malek
    Pages 1-6

  3. Head and Neck Cancer

    • Mark R. Gilbert, Chwee-Ming Lim, Seungwon Kim
    Pages 7-26

  4. Breast Cancer Invasion and Metastasis

    • Shane Stecklein, Hanan Elsarraj, Kelli Valdez, Arindam Paul, Fariba Behbod
    Pages 27-56

  5. Mouse Models of Pancreatic Cancer

    • Katherine T. Ostapoff, Michael T. Dellinger, Niranjan Awasthi, Rolf A. Brekken, Roderich E. Schwarz
    Pages 57-91

  6. Brain Metastasis

    • Yvonne Kienast
    Pages 93-115

  7. Pulmonary Metastasis

    • Anastasia Malek
    Pages 117-139

  8. Liver Metastases

    • Ann F. Chambers, Jason L. Townson
    Pages 141-161

  9. Malignant Pleural Effusion

    • Antonia Marazioti, Georgios T. Stathopoulos
    Pages 163-187

  10. Mathematical Modeling of the Metastatic Process

    • Jacob G. Scott, Philip Gerlee, David Basanta, Alexander G. Fletcher, Philip K. Maini, Alexander R.A. Anderson
    Pages 189-208

  11. Back Matter

    Pages 209-210
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Keywords

About this book

Metastatic dissemination of cancer is a main cause of cancer related deaths, therefore biological mechanisms implicated in metastatic process presents an essential object of cancer research. This research requires creation and utilization of adequate laboratory models. The book describes main approaches to model processes of metastatic cancer dissemination and metastases development. The book is structured in according with various metastatic pathways reflecting molecular specificity of metastatic process as well as anatomical specificity of aria of dissemination. Each chapter is introduced by short discussion of clinical aspects of certain metastatic pathway. Especial attention is paid for methods of visualization, quantification and analysis of the modeled metastases. Additional chapter is devoted to methods of mathematic modeling of tumor spread. The data presented in the book may be helpful for cancer researchers and oncologists.

Editors and Affiliations

  • Oncoendocrinology, Petrov Institute of Oncology, St Petersburg, Russia

    Anastasia Malek

Bibliographic Information

  • Book Title: Experimental Metastasis: Modeling and Analysis

  • Editors: Anastasia Malek

  • DOI: https://doi.org/10.1007/978-94-007-7835-1

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2013

  • Hardcover ISBN: 978-94-007-7834-4Published: 17 December 2013

  • Softcover ISBN: 978-94-024-0274-2Published: 17 September 2016

  • eBook ISBN: 978-94-007-7835-1Published: 02 December 2013

  • Edition Number: 1

  • Number of Pages: VIII, 210

  • Number of Illustrations: 39 b/w illustrations, 32 illustrations in colour

  • Topics: Cancer Research, Laboratory Medicine, Animal Models, Cell Culture

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