Biomarkers in Kidney Disease

1. Front Matter

   Pages i-xxviii

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2. General Aspects

   1. Front Matter

      Pages 1-1

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   2. Biomarkers in Kidney Transplantation

      • Mohsen Nafar, Shiva Samavat

      Pages 3-26

   3. Diagnostic Biomarkers of Acute Kidney Injury in Newborns

      • Athanasios Chalkias, Nicoletta Iacovidou

      Pages 27-40

   4. Osmolal Gap as a Biomarker in Kidney Injury: Focusing on the Differential Diagnosis of Metabolic Acidosis

      • Jeonghwan Lee, Nam Ju Heo, Jin Suk Han

      Pages 41-52

   5. Peritoneal Effluent Biomarker Discovery in Peritoneal Dialysis: The Omics Era

      • Deirisa Lopes Barreto, Dirk G. Struijk

      Pages 53-68

   6. Metabolomics and Stages of Chronic Kidney Disease

      • Toshihiro Kobayashi

      Pages 69-82

   7. Hypoxia as a Biomarker of Kidney Disease

      • Roger G. Evans, Julian A. Smith, Bruce S. Gardiner, David W. Smith, Amanda G. Thrift, Clive N. May et al.

      Pages 83-105

   8. MicroRNAs in Kidney Diseases

      • Grazia Serino, Fabio Sallustio, Francesco Paolo Schena

      Pages 107-138

   9. Serum Creatinine Trajectories in Kidney Disease

      • Macaulay Onuigbo, Nneoma Agbasi, Ogonna Oguejiofor, Emmanuel Okocha, Chinawaeze Aneke, Charles Odenigbo

      Pages 139-170

   10. Random Spot Urine Markers for Kidney and Their Applications

       • Maria Guedes-Marques, Carlos Botelho, Pedro Maia, Teresa Mendes, Armando Carreira

       Pages 171-204

   11. Overview of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker in Nephrology

       • Valeria Cernaro, Davide Bolignano, Antoine Buemi, Antonio Lacquaniti, Domenico Santoro, Michele Buemi

       Pages 205-227

   12. Chemokines as Potential Markers in Pediatric Renal Diseases

       • Ana Cristina Simões e Silva, André Barreto Pereira, Mauro Martins Teixeira, Antônio Lúcio Teixeira

       Pages 229-248

   13. Kidney and Neoplastic Disease: Overview with a Particular Interest to Interpretation of Cancer Biomarkers

       • Giuseppe Coppolino, Mariadelina Simeoni, Laura Rivoli, Chiara Summaria, Davide Bolignano

       Pages 249-268

3. Circulating and Body Fluid Biomarkers

   1. Front Matter

      Pages 269-269

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   2. Creatinine Assays in Early Infancy: How to Aim for a Moving Target

      • Karel Allegaert

      Pages 271-300

   3. Urinary Angiotensinogen as a Biomarker for Renal Disease

      • Zeynep Kendi Celebi, Siyar Erdogmus, Sule Sengul

      Pages 301-325

   4. Flow Cytometry of Urinary Leukocytes and Lymphocytes as a Biomarker of Renal Disease

      • Philipp Enghard, Birgit Rudolph, Jan Klocke, Gabriela Riemekasten

      Pages 327-345

   5. Proteome of Human Urinary Exosomes in Diabetic Nephropathy

      • Gloria Alvarez-Llamas, Irene Zubiri

      Pages 347-367

   6. Renal Biomarkers N-Acetyl-Beta-d-Glucosaminidase (NAG), Endothelin, and Their Application

      • Serap Çuhadar, Tuna Semerci

      Pages 369-396

In some countries such as the United States, kidney disease kills more people than cancers of the prostate or breast. In the United States for example there are over 15 million individuals with kidney disease. Translated to a worldwide basis, kidney disease of various aetiologies represent a significant burden on healthcare systems, affecting mortality, morbidity and also the family unit. It is therefore imperative that appropriate use is made of conventional, new and emerging biomarker platforms to aid diagnosis, treatment and an understanding of outcome measures.  Biomarkers in Kidney Disease embraces a holistic approach by combining information on different conditions that affect the kidney and the use of biomarkers. Biomarkers are described in terms of conventional, new and emerging analytes, techniques, platforms and applications. It covers the latest knowledge and trends. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.  

• Application to prognosis
• Biomarkers in disease
• Cancer Research
• Discovery of biomarkers
• High throughput technologies

  

• DeptofBiomedlSci,FacltyofSci&Technology, University of Westminster , London, United Kingdom

  Vinood B. Patel

• Department of Nutrition and Dietetics,Division of Diabetes and Nutritional Sciences, Faculty of Life Science and Medicine, King’s College London, London, United Kingdom

  Victor R. Preedy

Professor Victor R. Preedy is a senior faculty member of King's College London (Professor of Nutritional Biochemistry) and King's College Hospital (Professor of Clinical Biochemistry). He is attached to both the Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics. He is also Director of the Genomics Centre and a member of the School of Medicine. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1993 he gained his second doctoral degree, for his outstanding contribution to protein metabolism in health and disease. He has received membership and fellowship of a number of academic and professional bodies in the UK, including the Royal College of Pathologists, the Royal Institute of Public Health, and the Royal Society of Chemistry. Professor Preedy has published over 570 articles, which includes 165 peer-reviewed manuscripts based on original research, 100 reviews, and over 50 books and book volumes.  

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