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Corynebacterium diphtheriae and Related Toxigenic Species

Genomics, Pathogenicity and Applications

  • Several Corynebacterium glutamicum books have been published, but little to nothing about C. diphtheriae
  • A considerable number of research groups work on pili, surface structures, vaccines, distribution, host-pathogen-interactions, Fe metabolism, biotechnological applications (vectors systems to induce cell death, sialidase)
  • Recently published genome sequences give the unique opportunity to compare C. diphtheriae genomes
  • Includes supplementary material: sn.pub/extras

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Softcover Book USD 169.99
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Hardcover Book USD 169.99
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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xvii
  2. Diphtheria and its Etiological Agents

    • Andreas Burkovski
    Pages 1-14
  3. Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis—General Aspects

    • Ana Luíza de Mattos Guaraldi, Raphael Hirata, Vasco Ariston de Carvalho Azevedo
    Pages 15-37
  4. Corynephages: Infections of the Infectors

    • Vartul Sangal, Paul A. Hoskisson
    Pages 67-81
  5. Toxin Structure, Delivery and Action

    • Başak Varol, Bilge Özerman Edis, Muhammet Bektaş
    Pages 83-94
  6. Assembly and Function of Corynebacterium diphtheriae Pili

    • Melissa E. Reardon-Robinson, Hung Ton-That
    Pages 123-141
  7. Toxigenic Corynebacteria: Adhesion, Invasion and Host Response

    • Lisa Ott, Andreas Burkovski
    Pages 143-170
  8. Detection Methods for Laboratory Diagnosis of Diphtheria

    • Anja Berger, Michael Hogardt, Regina Konrad, Andreas Sing
    Pages 171-205
  9. Diphtheria Surveillance

    • Karen S. Wagner, Katherina Zakikhany, Joanne M. White, Gayatri Amirthalingam, Natasha S. Crowcroft, Androulla Efstratiou
    Pages 207-224
  10. History of Diphtheria Vaccine Development

    • Rino Rappuoli, Enrico Malito
    Pages 225-238
  11. Antimicrobial Susceptibility and Treatment

    • Aleksandra Anna Zasada
    Pages 239-246
  12. Sialidases of Corynebacteria and their Biotechnological Applications

    • Seonghun Kim, Doo-Byoung Oh, Ohsuk Kwon
    Pages 247-262
  13. Back Matter

    Pages 291-293

About this book

Corynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects.

Reviews

From the book reviews:

“It extensively examines the genomics, pathogenicity, diagnosis, and treatment of these bacteria as well as vaccine development. … an excellent resource for graduate, postdoctoral fellows, and basic scientists in microbiology, molecular genetics, or public health. It also would be a useful introductory tool for infectious disease fellows who are interested in pursuing public health and/or basic science research as part of a physician/scientist training pathway.” (Shirley F. Delair, Doody’s Book Reviews, August, 2014)

Editors and Affiliations

  • Friedrich-Alexander-Universität, Erlangen, Germany

    Andreas Burkovski

Bibliographic Information

  • Book Title: Corynebacterium diphtheriae and Related Toxigenic Species

  • Book Subtitle: Genomics, Pathogenicity and Applications

  • Editors: Andreas Burkovski

  • DOI: https://doi.org/10.1007/978-94-007-7624-1

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht (outside the USA) 2014

  • Hardcover ISBN: 978-94-007-7623-4Published: 18 November 2013

  • Softcover ISBN: 978-94-024-0192-9Published: 23 August 2016

  • eBook ISBN: 978-94-007-7624-1Published: 29 October 2013

  • Edition Number: 1

  • Number of Pages: XVII, 293

  • Number of Illustrations: 14 b/w illustrations, 8 illustrations in colour

  • Topics: Medical Microbiology, Bacteriology, Epidemiology, Parasitology, Microbial Genetics and Genomics

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access