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Bone Metastases

A translational and Clinical Approach

  • Book
  • © 2014

Overview

Editors:
  1. Vassilios Vassiliou

    1. Radiation Oncology, Bank of Cyprus Oncology Centre, Nicosia, Cyprus

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    You can also search for this editor in PubMed   Google Scholar

  2. Edward Chow

    1. Dept. Radiation Oncology, University of Toronto Sunnybrook Health Sciences Centre, Toronto, Canada

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    You can also search for this editor in PubMed   Google Scholar

  3. Dimitrios Kardamakis

    1. Dept. Radiation Oncology, University of Patras Medical School, Patras, Greece

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    You can also search for this editor in PubMed   Google Scholar

  • Highly useful textbook that will be of value to all oncologists, clinicians and researchers dealing with advanced cancer and bone metastases
  • Covers all topics related to the diagnosis, epidemiology, clinical picture, treatment and therapeutic response of metastatic bone disease
  • Book is an important niche for all professionals involved in cancer management to help ensure that the implementation of the variety of available treatments is done in the most effective and efficient manner
  • Contributors are experts in the field of metastatic bone disease
  • Includes supplementary material: sn.pub/extras

Part of the book series: Cancer Metastasis - Biology and Treatment (CMBT, volume 21)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-ix
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  2. Fundamental Concepts

    1. Front Matter

      Pages 1-1
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    2. Pathophysiology of Bone Metastases

      • John M. Chirgwin, G. David Roodman
      Pages 3-17

    3. Natural History, Prognosis, Clinical Features and Complications of Metastatic Bone Disease

      • Vassilios Vassiliou, Edward Chow, Dimitrios Kardamakis, Natalie Lauzon
      Pages 19-36

    4. Pain in Bone Metastases: Types and Mechanisms

      • Elaine Wallace, Marissa Slaven, Marissa Slaven, Marissa Slaven, Richard Wennberg, Richard Wennberg et al.
      Pages 37-49

  3. Investigations of Bone Metastases

    1. Front Matter

      Pages 51-51
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    2. Radiological Evaluations: Radiography, CT, MRI

      • Petros Polyviou, Demos Michaelides, Dimitrios Vomvas, Panteleimon Kountourakis, Vassilios Vassiliou, Dimitrios Andreopoulos
      Pages 53-70

    3. Nuclear Medicine Imaging Modalities: Bone Scintigraphy, PET-CT, SPECT-CT

      • Andor W. J. M. Glaudemans, Alberto Signore
      Pages 71-94

    4. Bone Biomarkers in Research and Clinical Practice

      • Janet E. Brown, Liang Zeng, Caroline Wilson
      Pages 95-124

    5. The Application of ‘Omics’ Techniques for Cancers That Metastasise to Bone: From Biological Mechanism to Biomarkers

      • Steven L. Wood, Janet E. Brown
      Pages 125-153

  4. Therapeutic Management

    1. Front Matter

      Pages 155-155
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    2. Analgesic Treatment of Bone Metastases

      • Sebastiano Mercadante
      Pages 157-173

    3. External Beam Radiotherapy and Bone Metastases

      • Candice Johnstone, Stephen T. Lutz
      Pages 175-185

    4. Radionuclide Therapy

      • Fabio M. Paes
      Pages 187-215

    5. Bisphosphonates in Bone Metastatic Setting

      • Grazia Armento, Marco Imperatori, Vladimir Virzì, Giuseppe Tonini, Daniele Santini
      Pages 217-234

    6. New Targeted Therapies for Bone Metastases

      • Allan Lipton, Luis Costa, Paul Sieber, William C. Dougall, Ada Braun
      Pages 235-246

    7. Systemic Therapy of Bone Metastases

      • Konstantinos Kamposioras, Evangelos Briasoulis
      Pages 247-273

    8. High-Intensity Focussed Ultrasound and Radio-Frequency Ablation for Bone Metastasis Treatment

      • Sheliza Halani, Jennifer Coccagna, Edward Chow, Kullervo Hynynen, Gregory J. Czarnota
      Pages 275-300

    9. Neuropathic Bone Metastases

      • Daniel Roos
      Pages 301-308

    10. Spinal Cord and Cauda Equina Compression

      • Ernesto Maranzano, Fabio Trippa
      Pages 309-321
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Keywords

About this book

The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.

Editors and Affiliations

  • Radiation Oncology, Bank of Cyprus Oncology Centre, Nicosia, Cyprus

    Vassilios Vassiliou

  • Dept. Radiation Oncology, University of Toronto Sunnybrook Health Sciences Centre, Toronto, Canada

    Edward Chow

  • Dept. Radiation Oncology, University of Patras Medical School, Patras, Greece

    Dimitrios Kardamakis

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