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Essentials of Mesenchymal Stem Cell Biology and Its Clinical Translation

  • Book
  • © 2013

Overview

Editors:
  1. Robert Chunhua Zhao

    1. Chinese Academy of Medical Sciences and Peking Union Medical College, Center of Excellence in Tissue Engineering, Institute of Basic Medical Sciences and School of Basic Medicine, Beijing, China, People's Republic

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  • Summarizes the current state of knowledge in Mesenchymal stem cell research
  • Presents the properties of Mesenchymal stem cell to give clues for effective therapy
  • Includes cutting-edge methods and protocols ?

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-viii
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  2. Basic Research/Mechanisms

    1. Front Matter

      Pages 1-1
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    2. A Historical Overview and Concepts of Mesenchymal Stem Cells

      • Shihua Wang, Robert Chunhua Zhao
      Pages 3-15

    3. Biology of MSCs Isolated from Different Tissues

      • Simone Pacini
      Pages 17-32

    4. Secretome of Mesenchymal Stem Cells

      • Yuan Xiao, Xin Li, Hong Hao, Yuqi Cui, Minjie Chen, Lingjun Liu et al.
      Pages 33-46

    5. Immunomodulatory Properties of Mesenchymal Stem Cells and Related Applications

      • Lianming Liao, Robert Chunhua Zhao
      Pages 47-62

    6. Mesenchymal Stem Cell Homing to Injured Tissues

      • Yaojiong Wu, Robert Chunhua Zhao
      Pages 63-74

    7. Major Signaling Pathways Regulating the Proliferation and Differentiation of Mesenchymal Stem Cells

      • Joseph D. Lamplot, Sahitya Denduluri, Xing Liu, Jinhua Wang, Liangjun Yin, Ruidong Li et al.
      Pages 75-100

    8. MicroRNAs in Mesenchymal Stem Cells

      • Mohammad T. Elnakish, Ibrahim A. Alhaider, Mahmood Khan
      Pages 101-126

    9. Genetic Modification of MSCs for Pharmacological Screening

      • Jie Qin, Martin Zenke
      Pages 127-138

    10. Control of Mesenchymal Stem Cells with Biomaterials

      • Sandeep M. Nalluri, Michael J. Hill, Debanjan Sarkar
      Pages 139-159

  3. Clinical Translation

    1. Front Matter

      Pages 161-161
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    2. Mesenchymal Stem Cells for Cardiovascular Disease

      • Wei Wu, Shuyang Zhang
      Pages 163-172

    3. Mesenchymal Stem Cells as Therapy for Graft Versus Host Disease: What Have We Learned?

      • Partow Kebriaei, Simon Robinson, Ian McNiece, Elizabeth Shpall
      Pages 173-190

    4. Mesenchymal Stem Cells for Liver Disease

      • Feng-chun Zhang
      Pages 191-197

    5. Mesenchymal Stem Cells for Bone Repair

      • Hongwei Ouyang, Xiaohui Zou, Boon Chin Heng, Weiliang Shen
      Pages 199-205

    6. Mesenchymal Stem Cells for Diabetes and Related Complications

      • Vladislav Volarevic, Majlinda Lako, Miodrag Stojkovic
      Pages 207-227

    7. Mesenchymal Stromal Cell (MSC) Therapy for Crohn’s Disease

      • Jignesh Dalal
      Pages 229-240

    8. The Summary of Stroke and Its Stem Cell Therapy

      • Renzhi Wang, Ming Feng, Xinjie Bao, Jian Guan, Yang liu, Jin Zhang
      Pages 241-252

    9. Mesenchymal Stem Cell Transplantation for Systemic Lupus Erythematosus

      • Lingyun Sun
      Pages 253-261
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Keywords

About this book

Mesenchymal stem cells (MSCs), a type of adult stem cells, have attracted the attention of scientists and physicians alike due to their unique biological properties and potential for disease treatment. As stem cell research is complex and progressing rapidly, it is important that the experts in this field share their views and perspectives. This book, co-edited by leading global researchers, is divided into three major sections and covers a broad range of topics concerning MSCs during their transition from benchside to bedside. The book is intended for researchers and clinicians in the field of stem cells. Dr. Robert Chunhua Zhao, MD. Ph.D is Cheung Kong Professor of Stem Cell Biology, Professor of Cell Biology at the Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, China Director of Center for Tissue Engineering, PUMC Chief scientist of 973 program Regional Editor of Stem Cells and Development.

Editors and Affiliations

  • Chinese Academy of Medical Sciences and Peking Union Medical College, Center of Excellence in Tissue Engineering, Institute of Basic Medical Sciences and School of Basic Medicine, Beijing, China, People's Republic

    Robert Chunhua Zhao

Bibliographic Information

  • Book Title: Essentials of Mesenchymal Stem Cell Biology and Its Clinical Translation

  • Editors: Robert Chunhua Zhao

  • DOI: https://doi.org/10.1007/978-94-007-6716-4

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2013

  • Hardcover ISBN: 978-94-007-6715-7Published: 18 June 2013

  • Softcover ISBN: 978-94-007-9900-4Published: 15 July 2015

  • eBook ISBN: 978-94-007-6716-4Published: 05 June 2013

  • Edition Number: 1

  • Number of Pages: VIII, 313

  • Number of Illustrations: 3 b/w illustrations, 18 illustrations in colour

  • Topics: Cell Biology, Stem Cells, Internal Medicine, Pathology

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