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  • © 2013

Trends in Stem Cell Proliferation and Cancer Research

  • State-of-the art information on proliferation mechanisms and cancer research including cancer stem cells, written by leaders of the field around the world
  • Comprehensive introduction with excellent figure material
  • The book is written in a way for addressing researchers from various disciplines
  • Audience includes university libraries, graduate students as well as researchers on post-doctoral and professor level, physicians interesting in novel approaches of therapy, academics and scientists of pharmaceutical industry, academics from related areas (biomedicine, pharmacy, chemistry), graduate student classes at the Universities of São Paulo and Belo Horizonte, international conferences and workshops (Cell Biology, medicine among others)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xviii
  2. Molecular Bases of Stem and Cancer Cell Proliferation

    1. Front Matter

      Pages 1-1
    2. An Introduction to Proliferation and Migration of Stem and Cancer Cells

      • Micheli Mainardi Pillat, Talita Glaser, Telma Tiemi Schwindt, Henning Ulrich
      Pages 3-12
    3. The Role of Cell Adhesion, Cell Junctions, and Extracellular Matrix in Development and Carcinogenesis

      • Anderson K. Santos, Fernanda M. P. Tonelli, Daniel A. F. Silva, Kátia N. Gomes, Luiz O. Ladeira, Rodrigo R. Resende
      Pages 13-49
    4. The Embryonic Rest Hypothesis of Cancer Development: 150 Years Later

      • Mariusz Z. Ratajczak, Maciej Tarnowski, Sylwia Borkowska, Karol Serwin
      Pages 51-63
    5. Are Calcium Channels More Important Than Calcium Influx for Cell Proliferation?

      • Anne-Sophie Borowiec, Gabriel Bidaux, Thierry Capiod
      Pages 65-92
    6. Role of Calcium Signaling in Stem and Cancer Cell Proliferation

      • Maria Jimena Amaya, Vânia A. M. Goulart, Anderson K. Santos, Alexandre H. Kihara, Silvia Guatimosim, Rodrigo R. Resende
      Pages 93-137
    7. Formation and Function of Lipid Droplets in Inflammation and Cancer

      • João P. B. Viola, André L. S. Cruz, Miriam B. F. Werneck, Patricia T. Bozza
      Pages 139-165
    8. The Role of Sphingolipids in Modulating Pluripotency of Stem Cells

      • Salman B. Hosain, Ronald A. Hill, Yong-Yu Liu
      Pages 167-191
  3. Signaling Pathways Underlying Tumor Genesis, Proliferation and Cell Death

    1. Front Matter

      Pages 193-193
    2. BH3-Only Proteins in Cancer and Apoptosis

      • Fabio Ghiotto, Claudya Tenca, Franco Fais, Silvia Bruno
      Pages 205-249
    3. Signalling Pathways of β-Catenin/JNK in Carcinogenesis

      • Eliana Kalakouti, Roya Babaei-Jadidi, Abdolrahman S. Nateri
      Pages 277-296
    4. The Regulation of the JNK Cascade and Programmed Cell Death by NF-κB: Mechanisms and Functions

      • Jason Bennett, Marta Moretti, Anil K. Thotakura, Laura Tornatore, Guido Franzoso
      Pages 297-336
  4. Functions and Dysfunctions of Physiological Processes Involved in Tumor Genesis and Malignancy

    1. Front Matter

      Pages 337-337
    2. Autophagy, Cell Death, and Cancer

      • Maryam Mehrpour, Ahmed Hamaï, Patrice Codogno
      Pages 359-390
    3. The Duality of Stem Cells: Double-Edged Sword in tumor Evolution and Treatment

      • Urška Tajnšek, Helena Motaln, Nataša Levičar, Ana Rotter, Tamara T. Lah
      Pages 391-433
    4. Implications of Glioblastoma Stem Cells in Chemoresistance

      • Suzana A. Kahn, Ema Torrado, Dora Brites, Vivaldo Moura-Neto
      Pages 435-462

About this book

The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced cancer therapy. Each chapter shall provide an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance

Editors and Affiliations

  • Instituto de Ciências Biológicas, Departamento de Bioquímica, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

    Rodrigo R. Resende

  • Depto. Bioquímica, Universidade de São Paulo Inst. Química, São Paulo, Brazil

    Henning Ulrich

Bibliographic Information

  • Book Title: Trends in Stem Cell Proliferation and Cancer Research

  • Editors: Rodrigo R. Resende, Henning Ulrich

  • DOI: https://doi.org/10.1007/978-94-007-6211-4

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2013

  • Hardcover ISBN: 978-94-007-6210-7Published: 22 August 2013

  • Softcover ISBN: 978-94-007-9742-0Published: 26 August 2015

  • eBook ISBN: 978-94-007-6211-4Published: 13 August 2013

  • Edition Number: 1

  • Number of Pages: XVIII, 661

  • Topics: Cancer Research, Stem Cells, Cell Biology, Biomedicine general

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access