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Reprogramming Microbial Metabolic Pathways

  • Book
  • © 2012

Overview

Editors:
  1. Xiaoyuan Wang

    1. , State Key Laboratory, Jiangnan University, Wuxi, China, People's Republic

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  2. Jian Chen

    1. School of Biotechnology, Jiangnan University, Wuxi, China, People's Republic

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    You can also search for this editor in PubMed   Google Scholar

  3. Peter Quinn

    1. , Div. of Life Sciences, King's College London, London, United Kingdom

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  • Methods for reprogramming industrial microorganisms
  • Methods to increase production of valuable biochemicals by fermentation
  • Information on metabolic engineering of different microorganisms

Part of the book series: Subcellular Biochemistry (SCBI, volume 64)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Emerging Methods for Redesigning Microorganisms

    1. Front Matter

      Pages 1-1
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    2. Towards Synthetic Gene Circuits with Enhancers: Biology’s Multi-input Integrators

      • Roee Amit
      Pages 3-20

    3. Elementary Mode Analysis: A Useful Metabolic Pathway Analysis Tool for Reprograming Microbial Metabolic Pathways

      • Cong T. Trinh, R. Adam Thompson
      Pages 21-42

    4. Evolutionary Engineering for Industrial Microbiology

      • Niti Vanee, Adam B. Fisher, Stephen S. Fong
      Pages 43-71

    5. Monitoring Microbial Diversity of Bioreactors Using Metagenomic Approaches

      • Joshua T. Ellis, Ronald C. Sims, Charles D. Miller
      Pages 73-94

    6. Synthetic Biology Triggers New Era of Antibiotics Development

      • Jianfeng Wang, Zhiqiang Xiong, Hailin Meng, Yiguang Wang, Yong Wang
      Pages 95-114

    7. Cascades and Networks of Regulatory Genes That Control Antibiotic Biosynthesis

      • Juan F. Martín, Paloma Liras
      Pages 115-138

    8. Systems Analysis of Microbial Adaptations to Simultaneous Stresses

      • Ross P. Carlson, Olusegun J. Oshota, Reed L. Taffs
      Pages 139-157

    9. Metabolic Reprogramming Under Microaerobic and Anaerobic Conditions in Bacteria

      • Yue Shan, Yong Lai, Aixin Yan
      Pages 159-179

    10. Tunable Promoters in Synthetic and Systems Biology

      • Tore Dehli, Christian Solem, Peter Ruhdal Jensen
      Pages 181-201

    11. Analysis of Corynebacterium glutamicum Promoters and Their Applications

      • Jan NeÅ¡vera, Jiří Holátko, Miroslav Pátek
      Pages 203-221

  3. Metabolic Engineering for Overproducing Chemicals and Materials

    1. Front Matter

      Pages 223-223
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  4. Metabolic Engineering for Overproducing Chemicals and Materials

    1. Production of Fumaric Acid by Fermentation

      • Adrie J. J. Straathof, Walter M. van Gulik
      Pages 225-240

    2. Metabolic Engineering of Microorganisms for Vitamin C Production

      • Jingwen Zhou, Guocheng Du, Jian Chen
      Pages 241-259

    3. Molecular Mechanisms and Metabolic Engineering of Glutamate Overproduction in Corynebacterium glutamicum

      • Takashi Hirasawa, Jongpill Kim, Tomokazu Shirai, Chikara Furusawa, Hiroshi Shimizu
      Pages 261-281

    4. Microbial Metabolic Engineering for L-Threonine Production

      • Xunyan Dong, Peter J. Quinn, Xiaoyuan Wang
      Pages 283-302

    5. The Production of Coenzyme Q10 in Microorganisms

      • Corinne P. Cluis, Dominic Pinel, Vincent J. Martin
      Pages 303-326

    6. Genetic Modification and Bioprocess Optimization for S-Adenosyl-L-methionine Biosynthesis

      • Xiaoqing Hu, Peter J. Quinn, Zhou Wang, Guoqiang Han, Xiaoyuan Wang
      Pages 327-341

    7. Manipulation of Ralstonia eutropha Carbon Storage Pathways to Produce Useful Bio-Based Products

      • Christopher J. Brigham, Natalia Zhila, Ekaterina Shishatskaya, Tatiana G. Volova, Anthony J. Sinskey
      Pages 343-366
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Keywords

About this book

Metabolic engineering has been developed over the past 20 years to become an important tool for the rational engineering of industrial microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of different metabolites. The overall goal is to achieve a better understanding of the metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved biochemical production.

Editors and Affiliations

  • , State Key Laboratory, Jiangnan University, Wuxi, China, People's Republic

    Xiaoyuan Wang

  • School of Biotechnology, Jiangnan University, Wuxi, China, People's Republic

    Jian Chen

  • , Div. of Life Sciences, King's College London, London, United Kingdom

    Peter Quinn

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