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Glioma Signaling

  • Book
  • © 2013

Overview

  • Important topics concerning molecular mechanisms responsible for glioma physiology and pathology
  • Unique occasion to get an inside signaling induced by extracellular nucleotides, growth factors and cytokines in glioma cells
  • New data concerning gliomas invasion and progression
  • Role of cytoplasmic transcription factors, as STAT and SMAD in glioma pathogenesis
  • Comparison of the nature of calcium signals in glioma cells with that in astrocytes and microglia

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 986)

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Table of contents (11 chapters)

Keywords

About this book

Glioma Signaling is a text reference on cellular signaling processes focused on the mechanism of nucleotide receptors activation by exogenic nucleotides and the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration changes, cellular growth, progression and invasion, as well as presents perspective concerning potential targets for glioma therapy.

Reviews

From the book reviews:

“This is the single best current reference on signal transduction mechanisms in gliomas 
 . The book is geared for biochemists, neurophysiologists, neurosurgeons, neurologists, students, and research fellows working on brain tumors from the point of view on diagnosis, pathophysiology, invasion, metastases, and potential molecular therapies of promise.” (Joseph J. Grenier, Amazon.com, July, 2014)

Editors and Affiliations

  • , Biochemistry, Nencki Institute of Experimental Biology, Warsaw, Poland

    Jolanta BaraƄska

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