Skip to main content
SpringerLink
Log in
Book cover
  • Book
  • © 2013

Epigenetics: Development and Disease

Editors:

  1. Tapas K. Kundu

    1. Advanced Scientific Research, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for, Bangalore, India

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Role of genome organisation as a basic platform of different epigenetic phenomena in the pathophysiological context
  • Epigenetic regulation of transcription Epigenetic contribution in development
  • Epigenetic mechanisms of important diseases such as diabetes, AIDS, Alzheimer?s disease, malaria and cancer Furthermore, the book has also revealed the epigenetic phenomena as target of new generation therapeutics

Part of the book series: Subcellular Biochemistry (SCBI, volume 61)

Sections

Buy it now

eBook USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (28 chapters)

  1. Front Matter

    Pages i-xxvi
    PDF

  2. Epigenetics and Evolution

    1. Front Matter

      Pages 1-1
      PDF

  3. EPIGENETICS AND EVOLUTION

    1. Chromatin Organization, Epigenetics and Differentiation: An Evolutionary Perspective

      • Sujata Kumari, Amrutha Swaminathan, Snehajyoti Chatterjee, Parijat Senapati, Ramachandran Boopathi, Tapas K. Kundu
      Pages 3-35

    3. Megabase Replication Domains Along the Human Genome: Relation to Chromatin Structure and Genome Organisation

      • Benjamin Audit, Lamia Zaghloul, Antoine Baker, Alain Arneodo, Chun-Long Chen, Yves d’Aubenton-Carafa et al.
      Pages 57-80

    4. Role of DNA Methyltransferases in Epigenetic Regulation in Bacteria

      • Ritesh Kumar, Desirazu N. Rao
      Pages 81-102

  4. Developmental Epigenetics

    1. Front Matter

      Pages 103-103
      PDF

  5. DEVELOPMENTAL EPIGENETICS

    2. Epigenetic Regulation of Male Germ Cell Differentiation

      • Oliver Meikar, Matteo Da Ros, Noora Kotaja
      Pages 119-138

    3. Epigenetic Regulation of Skeletal Muscle Development and Differentiation

      • Narendra Bharathy, Belinda Mei Tze Ling, Reshma Taneja
      Pages 139-150

    4. Small Changes, Big Effects: Chromatin Goes Aging

      • Asmitha Lazarus, Kushal Kr. Banerjee, Ullas Kolthur-Seetharam
      Pages 151-176

    5. Homeotic Gene Regulation: A Paradigm for Epigenetic Mechanisms Underlying Organismal Development

      • Navneet K. Matharu, Vasanthi Dasari, Rakesh K. Mishra
      Pages 177-207

  6. Epigenetics and Transcription Regulation

    1. Front Matter

      Pages 209-209
      PDF

  7. EPIGENETICS AND TRANSCRIPTION REGULATION

    1. Basic Mechanisms in RNA Polymerase I Transcription of the Ribosomal RNA Genes

      • Sarah J. Goodfellow, Joost C. B. M. Zomerdijk
      Pages 211-236

    5. Histone Variants and Transcription Regulation

      • Cindy Law, Peter Cheung
      Pages 319-341

    6. Noncoding RNAs in Chromatin Organization and Transcription Regulation: An Epigenetic View

      • Karthigeyan Dhanasekaran, Sujata Kumari, Chandrasekhar Kanduri
      Pages 343-372

    7. Chromatin Structure and Organization: The Relation with Gene Expression During Development and Disease

      • Benoît Moindrot, Philippe Bouvet, Fabien Mongelard
      Pages 373-396
Back to top

About this book

Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic material; DNA. The covalent modification of DNA, DNA associated histones, several non histone proteins as well as non coding RNA coherently operate to establish the epigenetic regulation of gene expression in physiological and pathophysiological conditions. This volume presents contributions from worldwide experts presenting their research and findings, including: the evolution of epigenetic machineries from archaea to higher eukaryotes; role of epigenetics in development and transcription regulation; epigenetic landscape of human disease; a chemical biology approach to understanding epigenetic phenomena; exploration of different small molecules as epigenetic therapies. This volume is aimed at students and researchers of chromatin biology and epigenetics and will also be of interest to a broader pharmaceutical audience.
Back to top

Keywords

Back to top

Editors and Affiliations

  • Advanced Scientific Research, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for, Bangalore, India

    Tapas K. Kundu

Back to top

Bibliographic Information

Back to top

Publish with us

Policies and ethics

Back to top
Access via your institution

Buy it now

eBook USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Search

Navigation