Skip to main content
  • Book
  • © 2012

Neuroblastoma

Editors:

  • Children with cancer
  • Pediatric physicians
  • Researchers in the field of pediatric cancer
  • Scientists involved in the development of cancer drugs

Part of the book series: Pediatric Cancer (PECA, volume 1)

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (24 chapters)

  1. Front Matter

    Pages i-xviii
  2. Introduction

    1. Front Matter

      Pages 1-1
    2. Introduction

      • M.A. Hayat
      Pages 3-7
  3. Diagnosis and Biomarkers

    1. Front Matter

      Pages 9-9
    2. Neuroblastoma Mouse Model

      • Hiroshi Iwakura, Takashi Akamizu
      Pages 31-38
    3. Orbital Metastasis in Neuroblastoma Patients

      • Stephen J. Smith, Brian G. Mohney
      Pages 39-45
    4. Pediatric Neuroblastoma: Molecular Detection of Minimal Residual Disease

      • Janine Stutterheim, Godelieve A.M. Tytgat, C. Ellen van der Schoot
      Pages 47-63
    5. A Comprehensive Tissue Microarray-Based FISH Screen of ALK Gene in Neuroblastomas

      • Marta Piqueras, Manish Mani Subramaniam, Arnaud Berthier, Samuel Navarro, Rosa Noguera
      Pages 65-75
  4. Therapy

    1. Front Matter

      Pages 77-77
    2. Neuroblastoma: Triptolide Therapy

      • Mara B. Antonoff, Ashok K. Saluja
      Pages 79-90
    3. Neuroblastoma: Ornithine Decarboxylase and Polyamines are Novel Targets for Therapeutic Intervention

      • André S. Bachmann, Dirk Geerts, Giselle L. Saulnier Sholler
      Pages 91-103
    4. Neuroblastoma: Antibody-Based Immunotherapy

      • Rossen M. Donev, Timothy R. Hughes, B. Paul Morgan
      Pages 105-113
    5. Targeting Multidrug Resistance in Neuroblastoma

      • Jamie I. Fletcher, Michelle Haber, Michelle J. Henderson, Murray D. Norris
      Pages 115-123
    6. Neuroblastoma: Perspectives for the Use of IL-21 in Immunotherapy

      • Michela Croce, Maria Valeria Corrias, Silvano Ferrini
      Pages 125-135
    7. Neuroblastoma: Role of Hypoxia and Hypoxia Inducible Factors in Tumor Progression

      • Erik Fredlund, Alexander Pietras, Annika Jögi, Sven PÃ¥hlman
      Pages 137-149
    8. Neuroblastoma: Role of GATA Transcription Factors

      • Victoria Hoene, Christof Dame
      Pages 151-159
    9. Neuroblastoma: Role of Clusterin as a Tumor Suppressor Gene

      • Arturo Sala, Korn-Anong Chaiwatanasirikul
      Pages 169-176

About this book

Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and  spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is  also included.

Editors and Affiliations

  • , Kean University, Room 213, Library building, Union, USA

    M.A. Hayat

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access