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  • © 2012

Interplay between Metal Ions and Nucleic Acids

  • Provides an up-to-date information on nucleic acid-metal ion interactions
  • Indicates future developments (nanotechnology) involving DNA and RNA
  • Valuable for teaching courses in Inorganic Biochemistry
  • Describes the analytical tools needed in nucleic acid chemistry
  • Describes comprehensively DNAzymes
  • Describes the technology of DNA

Part of the book series: Metal Ions in Life Sciences (MILS, volume 10)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xxxiii
  2. Characterization of Metal Ion-Nucleic Acid Interactions in Solution

    • Maria Pechlaner, Roland K. O. Sigel
    Pages 1-42
  3. Nucleic Acid-Metal Ion Interactions in the Solid State

    • Katsuyuki Aoki, Kazutaka Murayama
    Pages 43-102
  4. G-Quadruplexes and Metal Ions

    • Nancy H. Campbell, Stephen Neidle
    Pages 119-134
  5. Metal Ion-Mediated DNA-Protein Interactions

    • Barbara Zambelli, Francesco Musiani, Stefano Ciurli
    Pages 135-170
  6. Spectroscopic Investigations of Lanthanide Ion Binding to Nucleic Acids

    • Janet R. Morrow, Christopher M. Andolina
    Pages 171-199
  7. Enantioselective Catalysis at the DNA Scaffold

    • Almudena García-Fernández, Gerard Roelfes
    Pages 249-268
  8. Alternative DNA Base Pairing through Metal Coordination

    • Guido H. Clever, Mitsuhiko Shionoya
    Pages 269-294
  9. Metal-Mediated Base Pairs in Nucleic Acids with Purine- and Pyrimidine-Derived Nucleosides

    • Dominik A. Megger, Nicole Megger, Jens Müller
    Pages 295-317
  10. Metal Complex Derivatives of Peptide Nucleic Acids (PNA)

    • Roland Krämer, Andriy Mokhir
    Pages 319-340
  11. Back Matter

    Pages 341-353

About this book

Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.

Reviews

From the reviews:

“Bioinorganic chemistry is an exciting branch of chemistry with applications in new materials (including sensors and tissues), health (diagnosis and therapy), energy supplies (generation and storage), biological function, evolution, and beyond. The Sigel volumes are always a reliable way of keeping abreast of this rapidly expanding field. This one is no exception. ... This book is a good read and all bioinorganic chemists might wish it was on their shelves—not only for research, but as a resource for undergraduate teaching” (Peter J. Sadler, Angewandte Chemie International Edition, Vol. 51, 2012)

“‘Interplay between Metal Ions and Nucleic Acids’ … is for the entire community of researchers interested in metal-nucleic acid interactions. Its contents are highly topical, as they cover numerous relevant areas of a research that faces rapid growth. Reading this volume is a ‘must’ for scientists active in this field, and the editors should be congratulated on the fine selection of chapters and authors. … volume10 of MILS is among the very best books on this subject that have appeared in recent years!” (Bernhard Lippert, Inorganica Chimica Acta,Vol. 394, January, 2013)

"This book will be an excellent companion to postgraduate students and established researchers interested in the essential role that metal ions play in the structure and function of nucleic acids. In addition, this volume will be of interest to scientists working towards the use of nucleic acids for sensing and catalytic applications, as well as for the development of novel nanomaterials." (Ramon Vilar, Transition Metal Chemistry, Vol. 37, 2012)

Editors and Affiliations

  • Inorganic Chemistry, Chemistry, Universität Basel, Basel, Switzerland

    Astrid Sigel, Helmut Sigel

  • Organisch-Chemisches Institut, Universität Zürich, Zürich, Switzerland

    Roland K. O. Sigel

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access