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Tumors of the Central Nervous System, Volume 4

Brain Tumors (Part 2)

Editors:

  • Personalizing cancer care
  • Role of MicroRNA in distinguishing tumors
  • Genomic analysis of glioblastoma
  • Imaging to study brain cancer
  • Miolecular profiling of brain tumors

Part of the book series: Tumors of the Central Nervous System (TCNS, volume 4)

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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xxvi
  2. Introduction

    1. Front Matter

      Pages 1-1
    2. Epidemiology of Primary Brain Tumors

      • Isabelle Baldi, Hugues Loiseau
      Pages 3-13
    3. Supratentorial Primitive Neuroectodermal Tumors

      • Mohit Singh, Juliette Hukin
      Pages 15-24
    4. Epileptic Seizures and Supratentorial Brain Tumors in Children

      • Roberto Gaggero, Alessandro Consales, Francesca Fazzini, Maria Luisa Garrè, Pasquale Striano
      Pages 25-31
  3. Tumor to Tumor

    1. Front Matter

      Pages 33-33
  4. Tumor To Tumor

    1. Breast Cancer Metastasis to the Central Nervous System

      • Marc R. Matrana, Nuhad K. Ibrahim
      Pages 35-49
    2. Melanoma to Brain Metastasis: Photoacoustic Microscopy

      • Xinmai Yang, Mark Cohen
      Pages 51-56
  5. Biomarkers and Diagnosis

    1. Front Matter

      Pages 57-57
  6. Biomarkers And Diagnosis

    1. Extraaxial Brain Tumors: The Role of Genetic Polymorphisms

      • Luciana Oliveira de Almeida
      Pages 59-69
    2. Central Nervous System Germ Cell Tumor

      • Takamitsu Fujimaki
      Pages 71-77
    3. Microvascular Gene Changes in Malignant Brain Tumors

      • Matthew L. Dashnaw, Kevin A. Walter, Eleanor B. Carson-Walter
      Pages 79-86
    4. Role of MicroRNA in Glioma

      • Yongping You, Ning Liu, Chunsheng Kang, Peiyu Pu, Zhen Fu
      Pages 87-93
    5. Glioblastoma Multiforme: Cryopreservation of Brain Tumor-Initiating Cells (Method)

      • Tan Boon Toh, Yuk Kien Chong, Beng Ti Ang, Carol Tang
      Pages 95-101
    6. Relationship Between Molecular Oncology and Radiotherapy in Malignant Gliomas (An Overview)

      • Filippo Alongi, Arturo Chiti, Pierina Navarria, Marta Scorsetti
      Pages 103-110
    7. High-Grade Brain Tumours: Evaluation of New Brain Lesions by Amino Acid PET

      • Robert Pichler, Sabine Spiegl-Kreinecker, Gabriele Wurm
      Pages 111-117
  7. Imaging

    1. Front Matter

      Pages 129-129
    2. Molecular Imaging of Brain Tumours Using Single Domain Antibodies

      • Abedelnasser Abulrob, Umar Iqbal, Boguslaw Tomanek, Danica Stanimirovic
      Pages 131-141
    3. Quantitative Analysis of Pyramidal Tracts in Brain Tumor Patients Using Diffusion Tensor Imaging

      • Rubén Cárdenes, Emma Muñoz-Moreno, Rosario Sarabia-Herrero, Daniel Argibay-Quiñones, Marcos Martín-Fernández
      Pages 143-152

About this book

This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized. The need for supportive measures for survivors of brain cancer is pointed out, so is the quality of life monitoring. The need of rehabilitation therapy for patients with primary and metastatic brain tumors is also emphasized. Role of MicroRNA in distinguishing primary tumors from metastatic primary tumors is discussed. Advantages and limitations of chemotherapy (e.g., temozolomide and doxorubicin) are discussed. The complexity of tumor to tumor transfer is explained; examples discussed are: brain metastases from breast cancer and brain metastases fro non-small cell lung carcinoma. Identification and characterization of biomarkers, including those for metastatic brain tumors, are presented. Genomic analysis for identifying clinically relevant subtypes of glioblastoma is included. A large number of imaging modalities are detailed to study progression and invasion of gliomas

Reviews

From the reviews:

“The purpose is to address the main achievements in the neuroscience of tumors of the central nervous system. This volume deals with intracranial tumors. Neurosurgeons, neurologists, neuroradiologists, neuropathologists, molecular biologists, radiation therapists, and radiologists are the main audience. … The illustrations, text, and presentation are superb. Excellent in its presentation, content, and up-to-date information, this book deserves a spot in academic libraries serving neurosurgeons and neurologists.” (Celso Agner, Doody’s Review Service, March, 2012)

Editors and Affiliations

  • , Kean University, Room 213, Library building, Union, USA

    M.A. Hayat

Bibliographic Information

  • Book Title: Tumors of the Central Nervous System, Volume 4

  • Book Subtitle: Brain Tumors (Part 2)

  • Editors: M.A. Hayat

  • Series Title: Tumors of the Central Nervous System

  • DOI: https://doi.org/10.1007/978-94-007-1706-0

  • Publisher: Springer Dordrecht

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2012

  • Hardcover ISBN: 978-94-007-1705-3Published: 05 October 2011

  • Softcover ISBN: 978-94-007-3830-0Published: 29 November 2013

  • eBook ISBN: 978-94-007-1706-0Published: 15 September 2011

  • Series ISSN: 2215-096X

  • Series E-ISSN: 2215-0978

  • Edition Number: 1

  • Number of Pages: XXVI, 386

  • Topics: Cancer Research, Neuroradiology, Neurosurgery, Oncology, Pathology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access