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  • © 2011

Probiotic Bacteria and Enteric Infections

Cytoprotection by Probiotic Bacteria

  • Describes the possible mechanisms of action of probiotics that are not described by available books
  • Describes the probiotic–omics that are not described by any other book
  • Discusses on genetic engineering and designer probiotics that are not discussed in other books
  • Explains in details the benefits of probiotics and the recommended regime for their application in disease treatment
  • Presents recent data on immunological interference by probiotic bacteria
  • Includes supplementary material: sn.pub/extras

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Table of contents (19 chapters)

  1. Front Matter

    Pages 1-1
  2. Introduction and History of Probiotics

    1. Front Matter

      Pages 1-1
  3. The Gut Microorganisms and Probiotics

    1. Front Matter

      Pages 39-39
    2. The Intestinal Microbiota and Probiotics

      • Sofia D. Forssten, Sampo J. Lahtinen, Arthur C. Ouwehand
      Pages 41-63
    3. Ecology of Probiotics and Enteric Protection

      • Melanie Gagnon, Annina Zihler, Christophe Chassard, Christophe Lacroix
      Pages 65-85
  4. Pathophysiology of Enteric Disorders Due to Disturbed Microbiota

    1. Front Matter

      Pages 87-87
    2. Factors Causing Disturbances of the Gut Microbiota

      • Joshua J. Malago, Jos F. J. G. Koninkx
      Pages 89-111
    3. The Gut Microbiota, Probiotics and Infectious Disease

      • Cormac G. M. Gahan, Gerald C. O’Sullivan, J. Kevin Collins
      Pages 113-130
  5. Application of Molecular Biology and -omics of Probiotics in Enteric Protection

    1. Front Matter

      Pages 131-131
    2. Application of Molecular Biology and Genomics of Probiotics for Enteric Cytoprotection

      • Saloomeh Moslehi-Jenabian, Dennis Sandris Nielsen, Lene Jespersen
      Pages 133-153
    3. Application of Probiotic Proteomics in Enteric Cytoprotection

      • Hans Christian Beck, Søren Feddersen, Jørgen Petersen
      Pages 155-168
    4. Promoting Gut Health with Probiotic Metabolomics

      • Sebastiano Collino, François-Pierre J. Martin, Sunil Kochhar, Serge Rezzi
      Pages 169-185
  6. Probiotics, Gut Immunology and Enteric Protection

    1. Front Matter

      Pages 187-187
    2. Microbiota, Probiotics and Natural Immunity of the Gut

      • Eduardo Jorge Schiffrin, Anne Donnet-Hughes
      Pages 189-205
    3. Interaction of Probiotics with the Acquired Immune System in the Gut

      • Rossana D’Arienzo, Kathryne B. Schwartz, Mauro Rossi
      Pages 207-219
    4. The Protective Role of Probiotics in Disturbed Enteric Microbiota

      • Denis Roy, Véronique Delcenserie
      Pages 221-261
    5. Modulation of Immune System by Probiotics to Protect Against Enteric Disorders

      • Joshua J. Malago, Jos F. J. G. Koninkx
      Pages 263-286
  7. Probiotics for Enteric Therapy

    1. Front Matter

      Pages 287-287
    2. Probiotic-Pathogen Interactions and Enteric Cytoprotection

      • Joshua J. Malago, Jos F.J.G. Koninkx
      Pages 289-311

About this book

Every day many people suffer from intestinal diseases. These disorders can result from pathogens like bacteria, fungi, parasites and viruses, but the causes of non-infectious intestinal disorders and colorectal cancers remain to be elucidated. Disturbances to the normal gut flora (the microbiota) are central to the development of many, if not all, of these disorders.  

Disturbed gut microbiota is a prelude to public health issues like traveller’s-, antibiotic- and Clostridium difficile-associated diarrhoea, irritable bowel syndrome, inflammatory bowel disease, and colorectal cancers.  This book discusses the way intestinal disorders affect the microbiota, how the disturbed microbiotal balance leads to enteric disorders and the ways to prevent these disorders.

Further his book explores the potential of probiotics (live microorganisms that when ingested bring a health benefit) in treating enteric disorders by analysing the probiotic genome through proteomics, metabolomics and functional assays. Discussed is how the ingestion of specific microorganisms repairs the disturbed microbiota and subsequently ameliorates enteric disorders. Finally this book addresses how genetic engineering and biotechnology will contribute to the development of effective and safe designer probiotics.

Editors and Affiliations

  • Faculty of Veterinary Medicine, Department of Veterinary Pathology, Sokoine University of Agriculture, Chuo Kikuu, Morogoro, Tanzania

    J.J. Malago

  • Division Pathology, Dept of Pathobiology, Utrecht University, Utrecht, Netherlands

    J.F.J.G. Koninkx

  • Biotechnical Faculty, Zootechnical Department, University of Ljubljana, Domžale, Slovenia

    R. Marinsek-Logar

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access