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Detection of Biological Agents for the Prevention of Bioterrorism

  • Conference proceedings
  • © 2011

Overview

Editors:
  1. Joseph Banoub

    1. , Science Branch, Fisheries and Oceans Canada, St. John's, Canada

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  • MS strategies for the environmental biodetection
  • Clinical diagnosis (human body fluids)
  • Protection of food and water supplies
  • Detection of explosives, mycotoxins and chemical agents
  • Detection of extracted bacterial proteins
  • Detection of Biological markers for xenobiotic chemicals
  • 2D Tissue imaging for detection of cancer

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Table of contents (20 papers)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Broadband Analysis of Bioagents by Mass Spectrometry

    • Catherine Fenselau, Colin Wynne, Nathan Edwards
    Pages 1-12

  3. Hollow-Fiber Flow Field-Flow Fractionation for Mass Spectrometry: From Proteins to Whole Bacteria

    • Pierluigi Reschiglian, Andrea Zattoni, Diana Cristina Rambaldi, Aldo Roda, Myeong Hee Moon
    Pages 13-36

  4. Mass Spectrometry and Tandem Mass Spectrometry for Protein Biomarker Discovery and Bacterial Speciation

    • Alvin Fox, Karen Fox
    Pages 37-45

  5. Intact Cell/Spore Mass Spectrometry of Fusarium Macro Conidia for Fast Isolate and Species Differentiation

    • Hongjuan Dong, Martina Marchetti-Deschmann, Wolfgang Winkler, Hans Lohninger, Guenter Allmaier
    Pages 47-63

  6. Bacteriophage Amplification-Coupled Detection and Identification of Bacterial Pathogens

    • Christopher R. Cox, Kent J. Voorhees
    Pages 65-82

  7. Matrix Assisted Laser Desorption Ionization Mass Spectrometric Analysis of Bacillus anthracis: From Fingerprint Analysis of the Bacterium to Quantification of its Toxins in Clinical Samples

    • Adrian R. Woolfitt, Anne E. Boyer, Conrad P. Quinn, Alex R. Hoffmaster, Thomas R. Kozel, Barun K. De et al.
    Pages 83-97

  8. Microorganism Identification Based On MALDI-TOF-MS Fingerprints

    • Thomas Elssner, Markus Kostrzewa, Thomas Maier, Gary Kruppa
    Pages 99-113

  9. Mass Spectrometric Detection of Botulinum Neurotoxin by Measuring its Activity in Serum and Milk

    • Suzanne R. Kalb, James L. Pirkle, John R. Barr
    Pages 115-129

  10. Functional Assays for Ricin Detection

    • Eric Ezan, Elodie Duriez, François Fenaille, François Becher
    Pages 131-147

  11. Challenges of Detecting Bioterrorism Agents in Complex Matrices

    • Erica M. Hartmann, Rolf U. Halden
    Pages 149-162

  12. DESI-MS/MS of Chemical Warfare Agents and Related Compounds

    • Paul A. D’Agostino
    Pages 163-179

  13. Mass Spectrometry Applications for the Identification and Quantitation of Biomarkers Resulting from Human Exposure to Chemical Warfare Agents

    • J. Richard Smith, Benedict R. Capacio
    Pages 181-199

  14. Applications of Mass Spectrometry in Investigations of Alleged Use of Chemical Warfare Agents

    • Robert W. Read
    Pages 201-219

  15. Mass Spectrometry for the Analysis of Low Explosives

    • Bruce McCord, Megan Bottegal, John Mathis
    Pages 221-229

  16. Identification of the Bacterial Cellular Lipid Fraction by Using Fast GC × GC-MS and Innovative MS Libraries

    • Luigi Mondello, Peter Quinto Tranchida, Giorgia Purcaro, Chiara Fanali, Paola Dugo, Erminia La Camera et al.
    Pages 231-244

  17. Endotoxins in Environmental and Clinical Samples Assessed by GC-Tandem MS

    • Bogumila Szponar
    Pages 245-265

  18. Imaging Mass Spectrometry

    • Michelle L. Reyzer, Richard M. Caprioli
    Pages 267-283

  19. 2 and 3D TOF-SIMS Imaging for Biological Analysis

    • John S. Fletcher
    Pages 285-299

  20. Application of Mass Spectrometry for the Analysis of Vitellogenin, a Unique Biomarker for Xenobiotic Compounds

    • Alejandro M. Cohen, Joseph H. Banoub
    Pages 301-318
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Keywords

About this book

The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.

Editors and Affiliations

  • , Science Branch, Fisheries and Oceans Canada, St. John's, Canada

    Joseph Banoub

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