Overview
- Editors:
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Gordon S. Lynch
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, Department of Physiology, The University of Melbourne, Melbourne, Australia
- State-of-the-art information on aging and skeletal muscle
- Contributions from some of the world’s leading experts in skeletal muscle aging
- Identifies key neuromuscular mechanisms responsible for sarcopenia
- Identifies signalling pathways and targets for therapeutic intervention
- Information has relevance and broad application for researchers and practitioners involved with the study and treatment of aging and its effects on skeletal muscle
- Includes supplementary material: sn.pub/extras
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Table of contents (19 chapters)
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Front Matter
Pages i-xiii
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- Josep M. Argilés, Sílvia Busquets, Marcel Orpi, Roberto Serpe, Francisco J. López-Soriano
Pages 9-35
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- Carlos B. Mantilla, Gary C. Sieck
Pages 37-54
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- Alexander Cristea, David E. Vaillancourt, Lars Larsson
Pages 55-74
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- Stephen E. Alway, Parco M. Siu
Pages 173-206
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- Aaron P. Russell, Bertrand Lèger
Pages 207-221
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- Kathleen O’Connell, Philip Doran, Joan Gannon, Pamela Donoghue, Kay Ohlendieck
Pages 259-287
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- René Koopman, Lex B. Verdijk, Luc J. C. van Loon
Pages 289-315
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- Anne McArdle, Malcolm J. Jackson
Pages 317-331
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- Donato A. Rivas, Roger A. Fielding
Pages 333-371
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- John A. Faulkner, Christopher L. Mendias, Carol S. Davis, Susan V. Brooks
Pages 373-391
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- Chris D. McMahon, Thea Shavlakadze, Miranda D. Grounds
Pages 393-418
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- Craig McFarlane, Mridula Sharma, Ravi Kambadur
Pages 419-447
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- James G. Ryall, Gordon S. Lynch
Pages 449-471
About this book
Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence.
Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. There is an urgent need to better understand the neuromuscular mechanisms underlying age-related muscle wasting and to develop therapeutic strategies that can attenuate, prevent, or ultimately reverse sarcopenia. Significant research and development in academic and research institutions and in pharmaceutical companies is being directed to sarcopenia and to related health issues in order to develop and evaluate novel therapeutics.
This book provides the latest information on sarcopenia from leading international researchers studying the cellular and molecular mechanisms underlying age-related changes in skeletal muscle and identifies strategies to combat sarcopenia and related muscle wasting conditions and neuromuscular disorders. The book provides a vital resource for researchers and practitioners alike, with information relevant to gerontologists, geriatricians, sports medicine physicians, physiologists, neuroscientists, cell biologists, endocrinologists, physical therapists, allied health and musculoskeletal practitioners, strength and conditioning specialists, athletic trainers, and students of the medical and biomedical sciences.
Editors and Affiliations
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, Department of Physiology, The University of Melbourne, Melbourne, Australia
Gordon S. Lynch
