Cell and Organ Printing

1. Front Matter

   Pages i-xiv

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2. Biological Freeform Fabrication

   1. Front Matter

      Pages 1-1

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   2. 3D On-Demand Bioprinting for the Creation of Engineered Tissues

      • Seung-Schik Yoo, Samuel Polio

      Pages 3-19

3. Ink Jet Approaches

   1. Front Matter

      Pages 21-21

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   2. Reconstruction of Biological Three-Dimensional Tissues: Bioprinting and Biofabrication Using Inkjet Technology

      • Makoto Nakamura

      Pages 23-33

   3. Piezoelectric Inkjet Printing of Cells and Biomaterials

      • Rachel Saunders, Julie Gough, Brian Derby

      Pages 35-50

4. Modified Laser Induced Forward Transfer (LIFT) Approaches

   1. Front Matter

      Pages 51-51

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   2. Laser-Induced Forward Transfer: A Laser-Based Technique for Biomolecules Printing

      • P. Serra, M. Duocastella, J.M. Fernández-Pradas, J.L. Morenza

      Pages 53-80

   3. Biological Laser Printing (BioLP) for High Resolution Cell Deposition

      • Bradley R. Ringeisen, C.M. Othon, Xingjia Wu, D.B. Krizman, M.M. Darfler, J.J. Anders et al.

      Pages 81-93

   4. High-Throughput Biological Laser Printing: Droplet Ejection Mechanism, Integration of a Dedicated Workstation, and Bioprinting of Cells and Biomaterials

      • Fabien Guillemot, Bertrand Guillotin, Sylvain Catros, Agnès Souquet, Candice Mezel, Virginie Keriquel et al.

      Pages 95-113

   5. Absorbing-Film Assisted Laser Induced Forward Transfer of Sensitive Biological Subjects

      • B. Hopp, T. Smausz, A. Nógrádi

      Pages 115-134

5. Laser Guidance Approaches

   1. Front Matter

      Pages 135-135

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   2. Laser Guidance-Based Cell Micropatterning

      • Zhen Ma, Russell K. Pirlo, Julie X. Yun, Xiang Peng, Xiaocong Yuan, Bruce Z. Gao

      Pages 137-159

6. Self Organization and Biological Guidance

   1. Front Matter

      Pages 161-161

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   2. What Should We Print? Emerging Principles to Rationally Design Tissues Prone to Self-Organization

      • N.C. Rivron, J. Rouwkema, R. Truckenmüller, C.A. van Blitterswijk

      Pages 163-171

   3. Biological Guidance

      • Jan-Thorsten Schantz, Harvey Chim

      Pages 173-185

   4. Patterning Cells on Complex Curved Surface by Precision Spraying of Polymers

      • Mauris N. DeSilva

      Pages 187-202

   5. Fabrication of Growth Factor Array Using an Inkjet Printer

      • Kohei Watanabe, Tomoyo Fujiyama, Rina Mitsutake, Masaya Watanabe, Yukiko Tazaki, Takeshi Miyazaki et al.

      Pages 203-222

7. 3-Dimensional Scaffold Cell Printing

   1. Front Matter

      Pages 223-223

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   2. 3D-Fiber Deposition for Tissue Engineering and Organ Printing Applications

      • N.E. Fedorovich, L. Moroni, J. Malda, J. Alblas, C.A. van Blitterswijk, W.J.A. Dhert

      Pages 225-239

Cell and organ printing has become a hot topic of scientific pursuit. Since several early publications between 2000-2003 that demonstrated proof-of-concept, cell and organ printing has blossomed into a rich area for scientific exploration that is being performed by researchers across the globe. Research has thoroughly demonstrated that living cells can be printed via a number of actuations including electrospray, extrusion via micropens and ejection through photothermal, thermal or optical mechanisms. This topic has come of age and it is ripe for exploring the underpinnings of the research to date. We have included research that uses printing technology to deposit or guide cells for tissue engineering applications and for completeness, we have also included chapters describing bacteria printing, biomolecular printing that could be used to build growth factors or recruitment macromolecules into scaffolds, tissue microdissection, as well as live cell printing. The breadth of approaches includes 3D freeform fabrication, ink jet, laser guidance and modified laser direct write techniques. We hope that this book is not the final word but the first word, defining how these tools have been used to take the first steps towards the ultimate goal of creating heterogeneous tissue constructs. Only time will tell whether cell printers will truly become organ printers, but the technologies described in this book hold promise to achieve what the field of regenerative medicine requires - functional 3D scaffolds with multiple cell types differentiated into functional tissue!

• bacteria
• biology
• biomaterial
• biomolecule
• cell
• protein
• tissue

• Div. Chemistry, Code 6113, Naval Research Laboratory (NRL), Washington, USA

  Bradley R. Ringeisen, Peter K. Wu

• Chemical Dynamics and Diagnostics Branch, Code 6113, Naval Research Laboratory (NRL), Washington, USA

  Barry J. Spargo

Policies and ethics