Cervical Cancer: From Etiology to Prevention

1. Front Matter

   Pages i-xxx

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2. The Pathology of Cervical Neoplasia

   • Mark H. Stoler

   Pages 3-59

3. The Natural History of Cervical Cancer

   • Anthony B. Miller

   Pages 61-78

4. The Biology of Human Papillomavirus Infections

   • Patti E. Gravitt, Keerti V. Shah

   Pages 81-99

5. The Molecular Pathogenesis of Human Papillomavirus-Associated Cancer

   • Stephen T. Oh, Laimonis A. Laimins

   Pages 101-118

6. Chapter 5 Measurement of Exposure to Human Papillomaviruses

   • Patti E. Gravitt, Raphael P. Viscidi

   Pages 119-141

7. The Epidemiology of Human Papillomavirus Infections

   • Rachel L. Winer, Laura A. Koutsky

   Pages 143-187

8. The Etiology of Squamous Cell Cervical Cancer

   • F. Xavier Bosch

   Pages 191-216

9. The Epidemiology of Adenocarcinoma of the Cervix

   • Thomas E. Rohan

   Pages 217-234

10. Educational Strategies for the Prevention of Cervical Cancer

    • Electra D. Paskett, Mary Ellen Wewers, Mack T. Ruffin IV

    Pages 237-259

11. Screening for Cervical Cancer

    • Jack Cuzick

    Pages 261-299

12. Chemoprevention of Cervical Cancer

    • Michele Follen M.D., Frank L. Meyskens Jr., E. Neely Atkinson, David Schottenfeld

    Pages 301-323

13. Preventive Human Papillomavirus Vaccines

    • John T. Schiller, Douglas R. Lowy

    Pages 325-343

14. Therapeutic Human Papillomavirus Vaccines

    • Morris Ling, T.-C. Wu

    Pages 345-375

15. Policies for Implementing Cervical Cancer Preventive and Control Strategies

    • Robert A. Hiatt, Jon F. Kerner

    Pages 377-402

16. Back Matter

    Pages 403-415

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The last few years have seen enormous progress in terms of our understanding of the etiology and pathogenesis of cervical cancer (particularly with respect to the role of human papillomaviruses), and this has opened up new avenues for prevention. Additionally, there have been further refinements of existing technologies for cervical cancer control. To read about the state of the art on cervical cancer, health professionals have to locate individual articles and reviews of specific topics. In recognition of this, we propose to produce a book that will bring together in one place reviews of the contribution of descriptive and analytical epidemiological research to our understanding of cervical cancer etiology, as well as research on the application of that knowledge (plus knowledge gained from basic science investigations) to prevention through screening, chemoprevention, and vaccine development. The proposed book will include authoritative reviews by scientists working on the disciplines that are pertinent to the topic of the epidemiology and prevention of cervical cancer.

"In this book, Drs. Rohan and Shah have produced a comprehensive treatment of the evidence relating to cervical cancer etiology and prevention. They have done so by assembling a team of leading cervical cancer researchers who have addressed the biology and natural history of human papillomavirus infection and cervical cancer, as well as the etiology of cervical cancer, approaches to its prevention, and the policy issues relating to implementation of preventive strategies. The book is very timely in that it synthesizes the substantial advances in knowledge of these topics that have taken place in recent years, advances that put us on the threshold of a new era in cervical cancer prevention and control."
(Harald zur Hausen, M.D., D.Sc.)

• Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, USA

  Thomas E. Rohan

• Departments of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA

  Keerti V. Shah

Policies and ethics