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Stem Cell Biology in Health and Disease

  • Book
  • © 2010

Overview

Editors:
  1. Thomas Dittmar

    1. Inst. Immunologie, Universität Witten/Herdecke, Witten, Germany

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  2. Kurt S. Zanker

    1. Inst. Immunologie, Universität Witten/Herdecke, Witten, Germany

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    You can also search for this editor in PubMed   Google Scholar

  • Up-to-date information on current research in stem cell biology
  • Reflecting the two sides of stem cells
  • Summarizes current strategies on the use of embryonic stem cells and embryonic-like stem cells in regenerative medical purposes
  • Summarizes current strategies on the elimination of cancer stem cellls

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xii
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  2. Bone marrow-derived stem cells

    1. Front Matter

      Pages 9-9
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    2. Introduction

      • Thomas Dittmar, Kurt S. Zänker
      Pages 1-7

    3. Hematopoietic Stem and Progenitor Cells in Clinical Use – Transplantation and Mobilization

      • Michael Punzel
      Pages 11-26

    4. Ex Vivo Expansion of HSPCs

      • Yaming Wei, Xin Ye
      Pages 27-56

    5. Modulation of Hematopoietic Stem/Progenitor Cell Migration

      • Thomas Dittmar, Susannah H. Kassmer, Benjamin Kasenda, Jeanette Seidel, Bernd Niggemann, Kurt S. Zänker
      Pages 57-77

    6. Properties of Mesenchymal Stem Cells to Consider for Cancer Cell Therapy

      • John Stagg, Sandra Pommey
      Pages 79-98

  3. Embryonic Stem Cells

    1. Front Matter

      Pages 99-99
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    2. Alternative Embryonic Stem Cell Sources

      • Tomo Šarić, Narges Zare Mehrjardi, Jürgen Hescheler
      Pages 101-143

    3. Cell Therapy in Parkinson’s Disease

      • R. Laguna Goya, R.A. Barker
      Pages 145-154

    4. Transplantation of Stem Cells and Their Derivatives in the Treatment of Multiple Sclerosis

      • Eric C. Larsen, Ian D. Duncan
      Pages 155-181

  4. Cancer Stem Cells

    1. Front Matter

      Pages 183-183
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    2. Cancer: A Stem Cell-based Disease?

      • James E. Trosko
      Pages 185-222

    3. Stem Cell Niche Versus Cancer Stem Cell Niche – Differences and Similarities

      • Bruce C. Baguley, Graeme J. Finlay
      Pages 223-233

    4. The Chronically Inflamed Microenvironment and Cancer Stem Cells

      • Hanchen Li, Calin Stoicov, Xueli Fan, Jan Cerny, Jean Marie Houghton
      Pages 235-250

    5. Does the Chronically Inflamed Periodontium Harbour Cancer Stem Cells?

      • Wolf-Dieter Grimm, Wolfgang H. Arnold, Sebastian Becher, Aous Dannan, Georg Gassmann, Stathis Philippou et al.
      Pages 251-279

    6. Leukemia Stem Cells

      • Markus Müschen
      Pages 281-294

    7. Cancer Stem Cells in Solid Tumors

      • Melia G. Nafus, Alexander Yu. Nikitin
      Pages 295-326

    8. “One for All” or “All for One”? – The Necessity of Cancer Stem Cell Diversity in Metastasis Formation and Cancer Relapse

      • Thomas Dittmar, Christa Nagler, Sarah Schwitalla, Kathrin Krause, Jeanette Seidel, Georg Reith et al.
      Pages 327-356

    9. Elimination of Cancer Stem Cells

      • A. Sagrera, J. Pérez-Losada, M. Pérez-Caro, R. Jiménez, I. Sánchez-García, C. Cobaleda
      Pages 357-384
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Keywords

About this book

Stem Cell Biology in Health and Disease presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss:

- the controversial debate on the great expectations concerning stem cell based regeneration therapies raised by the pluripotency of various stem cells.
- the advantages and concerns about embryonic stem cells (ES cells), induced pluripotent stem cells (iPS cells) and adult stem cells, such as bone marrow-derived stem cells (BMDCs).
- the type of stem cells, which has become of interest in the past decade, namely so-called cancer stem cells (CSCs). CSCs are now in the focus of cancer research since the eradication of tumour initiating cells would raise the changes of definitely cure cancer.

Professor Dittmar and Professor Zänker have edited a must-read book for researchers and professionals working in the field of regenerative medicine and/or cancer.

Reviews

Aus den Rezensionen: “Ein Überblick zu Stammzellen in ihren verschiedenen Rollen bei Regeneration und Krebs? Ambitioniert. ... Das liegt einerseits am medium Buch. Ästhetisch ansprechend, nur dauert es eine Weile, bis es zusammengestellt und gedruckt ist. ... Viele wissenschaftliche Erkenntnisse sind beeindruckend, wenn sie zum ersten Mal geäußert werden ... Im einleitenden geschichtlichen Überblick stammen die aktuellsten Quellenangaben aus dem Jahr 2008. ... Als Aufsatzsammlung von Wissenschaftlern für Wissenschaftler will das Buch wiederum zu grundsätzlich und umfassend sein. ... Ein aktuelles und spannendes Thema ...“ (in: Transkript, March/2010, Issue 3, S. 67)

Editors and Affiliations

  • Inst. Immunologie, Universität Witten/Herdecke, Witten, Germany

    Thomas Dittmar, Kurt S. Zanker

Bibliographic Information

  • Book Title: Stem Cell Biology in Health and Disease

  • Editors: Thomas Dittmar, Kurt S. Zanker

  • DOI: https://doi.org/10.1007/978-90-481-3040-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2010

  • Hardcover ISBN: 978-90-481-3039-9Published: 06 November 2009

  • Softcover ISBN: 978-94-007-9113-8Published: 16 November 2014

  • eBook ISBN: 978-90-481-3040-5Published: 13 October 2009

  • Edition Number: 1

  • Number of Pages: XII, 426

  • Topics: Cancer Research, Oncology, Stem Cells, Immunology, Transplant Surgery

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