Neonatal Pain

1. Front Matter

   Pages I-XV

   PDF

2. Introduction: Pain and Suffering from the Womb Onwards?

   1. Introduction: Pain and Suffering from the Womb Onwards?

      • G. Buonocore, C. V. Bellieni

      Pages 1-2

3. Delivery and Pain

   1. Front Matter

      Pages 3-3

      PDF

   2. Gonadal Hormones and Pain Modulation

      • A. M. Aloisi, I. Ceccarelli

      Pages 5-10

   3. Stress and Pregnancy: CRF as Biochemical Marker

      • P. Florio, F. M. Reis, S. Luisi, M. De Bonis, I. Zerbetto, R. Battista et al.

      Pages 11-23

   4. Pain Control During Labour

      • C. Benedetto, M. Zonca, L. Bonino, S. Blefari, E. Gollo

      Pages 25-28

4. Fetal Pain

   1. Front Matter

      Pages 29-29

      PDF

   2. Ultrasound and Fetal Stress: Study of the Fetal Blink-Startle Reflex Evoked by Acoustic Stimuli

      • C. Bocchi, F. M. Severi, L. Bruni, G. Filardi, A. Delia, C. Boni et al.

      Pages 31-33

   3. Prenatal Affective Exchanges and Their Subsequent Effects in Postnatal Life

      • C. Dolto

      Pages 35-44

   4. Pain in the Fetus

      • G. Noia, E. Cesari, M. S. Ligato, D. Visconti, M. Tintoni, I. Mappa et al.

      Pages 45-55

   5. New Insights into Prenatal Stress: Immediate and Long-Term Effects on the Fetus and Their Timing

      • K. O’Donnell, V. Glover

      Pages 57-64

5. Neonatal Pain

   1. Front Matter

      Pages 65-65

      PDF

   2. Pain Assessment and Spectral Analysis of Neonatal Crying

      • C. V. Bellieni, G. Buonocore

      Pages 67-71

   3. Analgesic Procedures in Newborns

      • L. Giuntini, G. Amato

      Pages 73-81

   4. Nonpharmacological Treatment of Neonatal Pain

      • R. Carbajal

      Pages 83-97

   5. Sensory Saturation: An Analgesic Method

      • C. V. Bellieni, M. Maffei, G. Buonocore

      Pages 99-102

   6. Pharmacologic Analgesia in the Newborn

      • A. M. Guadagni

      Pages 103-108

   7. Physical Stress Risk Agents in Incubators

      • R. Sisto

      Pages 109-119

6. Pain: a Risk Factor for Brain Damage

   1. Front Matter

      Pages 121-121

      PDF

   2. Neonatal Stressors

      • M. Delivoria-Papadopoulos, O. P. Mishra

      Pages 123-130

For many years we have been talking about a very special patient, the embryo; and the numerous and encouraging successes brought about by embryofetal medicine in the application of both noninvasive therapies and invasive ultrasound-guided tre- ment are well known. On the other hand, it is more and more often the case today that the small patients in neonatal care are premature babies who have come to the world at a particul- ly low gestational age. This allows us to observe the continuity between the ph- es of growth inside the maternal uterus and after birth, which arrives at the correct moment for some lucky fetuses, for others very early, and for some altogether too soon. The neonatologists have the arduous task of sustaining these little patients in their strivings to survive, registering their energy and their vital dynamism, stu- ing the progressive development of the anatomical structures and the improvement of their physiology, verifying day by day the presence – sometimes fragile, so- times extremely resistant, but always human – of a child. A long line research has shown how, from the first moment onwards in that process of perfectly coordinated development that characterizes the life of the embryo, a human being gradually emerges who is increasingly able to interact with his or her environment.

• Ethics
• Pain
• bioethics
• brain damage
• diagnosis
• fetus
• newborn
• ultrasound

From the reviews:

"This book, authored mostly by Italian physicians and scientists, describes pain in the fetus and neonate and its consequences in later life. … This is a good resource for neonatologists, obstetricians, pediatric surgeons, and other medical and nursing professionals in the field of perinatal care. … This is a good book on many aspects of fetal and neonatal pain that provides a fairly extensive review of the world literature on this controversial subject." (Jay P. Goldsmith, Doody’s Review Service, March, 2008)

“Neonatal Pain … presents nineteen contributions by an international group of physicians and scientists which describe and review recent medical studies indicating that fetuses and newborns do suffer pain and stress and that these stresses may have adverse effects on the children’s mental, physical, and emotional development. … provides an accessible and valuable resource for the nonscientific expert. The authors also … highlight potential health problems in the fetus and developing child that may arise in response to pain and stress.” (Katherine Helming, The National Catholic Bioethics Quarterly, Winter, 2009)

• Department of Pediatrics, Obstetrics and Reproduction Medicine, University of Siena, Siena, Italy

  Giuseppe Buonocore, Carlo V. Bellieni

Giuseppe Buonocore is full professor of Pediatrics and Director of the Unit of Neonatology of the University Hospital of Siena.

He is involved in the coordination of numerous pan-European clinical trials, as for example of the European scientific network EURAIBI (acronym for EURope Against Infant Brain Injury). His research interests are in the mechanisms of cell damage in the neonatal brain, with special reference to hypoxia, the role of oxidant radicals in neonatal diseases and in babies with birth asphyxia. Additional research interest fields are ethics in perinatology and fetal and neonatal pain prevention. His research team is funded by several agencies including the Italian Ministry of University and Scientific Research -cofinance scheme for research projects of high national interest as well as European Community : NEOBRAIN project.

Author of more than 100 scientific publications in international journals with IF ("Pediatric Research", "Biology of Neonate", "Free Radical Biology and Medicine","Acta Pediatrica", "Archives Diseases in Children", " Journal of Pediatrics" and others).

He is Past-President of the European Society for Pediatric Research, and currently a member of the Editorial Board of "Biology of Neonate".

Dr. Bellieni, author of a chapter in the Encyclopedia of Pain, works in the University Hospital of Siena as well, and is a member of several national and international societiesm suche as the European Society of Pediatric Research, the Italian Society of Pediatrics and the Italian Society of Neonatology.

Policies and ethics