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Recent Trends in Antifungal Agents and Antifungal Therapy

  • Book
  • © 2016

Overview

Editors:
  1. Amit Basak

    1. Department of Chemistry Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur, Kharagpur, India

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  2. Ranadhir Chakraborty

    1. Department of Biotechnolgy, University of North Bengal, Darjeeling, India

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  3. Santi M. Mandal

    1. Department of Microbiology, Vidyasagar University, Midnapore, India

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  • Presents a top to bottom outline of natural and synthetic antifungal compounds

  • Elaborates on the past and recent updates on antifungal peptides with their structure-function relationship

  • Focuses on antifungal chemotherapy, structure-activity/function relationship and synthetic analogues which help in development of new compounds and drugs

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-ix
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  2. Fungi Fights Fungi: Tip-off in Antifungal Chemotherapy

    • Santi M. Mandal, Anupam Roy, Debarati Paul, Suresh Korpole, Shanker Lal Shrivastava, Ranadhir Chakraborty et al.
    Pages 1-27

  3. Essential Oil and Antifungal Therapy

    • Mohammad Moghaddam, Leila Mehdizadeh
    Pages 29-74

  4. Antifungal Peptides with Potential Against Pathogenic Fungi

    • Camila G. Freitas, Octávio L. Franco
    Pages 75-95

  5. Lipopeptides: Status and Strategies to Control Fungal Infection

    • Piyush Baindara, Suresh Korpole
    Pages 97-121

  6. Plant-Derived Antifungal Agents: Past and Recent Developments

    • G. M. Vidyasagar
    Pages 123-147

  7. Recent Advancements in Combinational Antifungal Therapy and Immunotherapy

    • Sudarshan Singh Rathore, Jayapradha Ramakrishnan, Thiagarajan Raman
    Pages 149-173

  8. Nanocarriers of Antifungal Agents

    • Sevgi Güngör, M. Sedef Erdal
    Pages 175-190

  9. Synthetic Compounds for Antifungal Chemotherapy

    • Rupa Pegu, Rohan Borah, Sanjay Pratihar
    Pages 191-215

  10. Antifungal Therapy in Eye Infections: New Drugs, New Trends

    • Joveeta Joseph, Savitri Sharma
    Pages 217-236

  11. Antifungal Susceptibility Testing of Dermatophytes

    • Indira Gadangi
    Pages 237-250
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Keywords

About this book

Fungal infections have taken a new spectrum due to the increased incidence of multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat fungal infections is also narrow because of lesser probability of discovering drugs that would bypass affecting human cells and target fungal cells producing fewer side effects in patients. An approach has gained prominence in research is to look for bioactive antifungal compounds from natural to synthetic sources. It is necessary to discover new classes of antifungals to control the recent emergence of multi-drug resistant fungal infections. This book proposed a details top to bottom outline of antifungal compounds derived naturally or synthetically. The details of their modifications or synthetic analogues have been described, helpful to understand the structure-activity relationship which leads to new compound development in antifungal chemotherapy. Each chapter begins with a comprehensive, top-bottom in-depth discussion of antifungal agents with updated bibliographic references. This compendium will serve as a companion not only for Scientists, Researchers, and Professors, Medical Practitioners but also a valuable reference text for the university students. 

Editors and Affiliations

  • Department of Chemistry Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur, Kharagpur, India

    Amit Basak

  • Department of Biotechnolgy, University of North Bengal, Darjeeling, India

    Ranadhir Chakraborty

  • Department of Microbiology, Vidyasagar University, Midnapore, India

    Santi M. Mandal

About the editors

Amit Basak, currently Professor of Chemistry and Chairman, School of Bioscience, IIT Kharagpur,obtained his Ph.D. (natural product chemistry) from Calcutta University and D. Phil. (penicillin biosynthesis) from University of Oxford. He then worked on clavulanic acid biosynthesis as a postdoctoral fellow at the Johns Hopkins University. His research interests involve understanding the mechanism of diradical generating reactions and their applications, development of enzyme inhibitors as antimicrobial agents and molecular capture chemistry. He has received several prestigious awards and fellowships for his research contribution.

Ranadhir Chakraborty was born in Darjeeling. He has worked for Ph.D in the Department of Microbiology, Bose Institute, Kolkata, India. He is at present serving the Department of Biotechnology, University of North Bengal, in the capacity of Professor and Head. He maintained a perfect blend of classical and modern microbiology in his ongoing journey of Science. He probes some basic scientific problems including antimicrobial resistance with cutting edge technology of every passing time period.

Santi M. Mandal obtained his Ph D in the field of Molecular Microbiology and continuing research with major focus in Antimicrobial Chemotherapy. He visited UTMB-USA and NUS-Singapore for his postdoctoral training. Recently, he is working as an Assistant Professor of Microbiology at Vidyasagar University, India. He has published more than 90 research papers in reputed journals and conferred upon several prestigious awards for his research contribution.

Bibliographic Information

  • Book Title: Recent Trends in Antifungal Agents and Antifungal Therapy

  • Editors: Amit Basak, Ranadhir Chakraborty, Santi M. Mandal

  • DOI: https://doi.org/10.1007/978-81-322-2782-3

  • Publisher: Springer New Delhi

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer India 2016

  • Hardcover ISBN: 978-81-322-2780-9Published: 05 October 2016

  • Softcover ISBN: 978-81-322-3835-5Published: 15 June 2018

  • eBook ISBN: 978-81-322-2782-3Published: 21 September 2016

  • Edition Number: 1

  • Number of Pages: IX, 250

  • Number of Illustrations: 109 b/w illustrations, 10 illustrations in colour

  • Topics: Mycology, Bacteriology, Biological Microscopy, Immunology

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