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Signal Transduction in Affective Disorders

  • Conference proceedings
  • © 1998

Overview

Editors:
  1. Hiroki Ozawa

    1. Department of Neuropsychiatry, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido 060, Japan

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  2. Toshikazu Saito

    1. Department of Occupational Therapy, School of Health Science, Sapporo Medical University, Sapporo, Hokkaido 060, Japan

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  3. Naohiko Takahata

    1. Department of Neuropsychiatry, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido 060, Japan

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  • Brings up-to-date reviews by young scientists who work actively in basic and clinical neuroscience.

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Table of contents (10 papers)

  1. Front Matter

    Pages II-X
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  2. Effects of Antidepressants on Transmembrane Signaling

    • Toshikazu Saito
    Pages 1-6

  3. Serotonergic and Noradrenergic Neuromodulation in the Hippocampus and the Mechanism of Action of Antidepressants

    • Osamu Tajima, Shinichi Murata, Tsukasa Mitsuhashi, Kenichi Takemasa
    Pages 7-20

  4. Serotonin-2A Receptor Function in Affective Disorders

    • Ichiro Kusumi, Tsukasa Koyama
    Pages 21-34

  5. Immunological Aspects of Mood Disorders: Interaction Between Cytokines and Intracellular Calcium Signaling

    • Ariyuki Kagaya, Shigeto Yamawaki
    Pages 35-47

  6. The Role of G Proteins in the Pathophysiology and Treatment of Affective Disorders

    • Hiroki Ozawa, Naohiko Takahata
    Pages 49-67

  7. Protein Phosphorylation System in the Mechanism of Action of Antidepressants

    • S. Miyamoto, M. Asakura
    Pages 69-84

  8. Stress and BDNF Signal Transduction: Implications for Stress-Related Psychiatric Disorders

    • Shigeru Morinobu, Masashi Nibuya, Ronald S. Duman
    Pages 85-95

  9. Postreceptor Signal-Transduction Systems as Potential Targets of Lithium

    • Y. Odagaki, N. Nishi, T. Koyama
    Pages 97-119

  10. Participation of Cytoskeletal Elements in Neuronal Signal Transduction: New Insight into the Molecular Basis of Antidepressant Action

    • Shinichi Hatta, Hideyo Ohshika
    Pages 121-132

  11. In Vivo Investigations of Signal-Transduction Systems in Affective Disorders by Magnetic Resonance Spectroscopy

    • Tadafumi Kato
    Pages 133-146
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Keywords

About this book

Recent progress in brain science has been remarkable, especially with regard to advances in the area of neuroscience. Particularly in the past decade, there have been many important discoveries about signal transduction in the brain. With this background, biological research in affective disorders has become well developed in relation to neural signaling. However, this field is fairly hard to understand comprehensively, and there is relatively little integrative work with clinical psychiatry in spite of the involvement of a wide variety of scien­ tific disciplines. This monograph brings together up-to-date reviews from several young Japanese scientists who work in basic and clinical neuroscience. The intention is to explain in plain language the information that has evolved on signal transduction in terms of the biological abnormalities and mechanisms of anti­ depressants. The model shown on the cover (and on page 24) is intended to help the reader understand signal transduction in the brain and the patho­ physiology of affective disorders as well as the mechanisms of antidepressants.

Editors and Affiliations

  • Department of Neuropsychiatry, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido 060, Japan

    Hiroki Ozawa, Naohiko Takahata

  • Department of Occupational Therapy, School of Health Science, Sapporo Medical University, Sapporo, Hokkaido 060, Japan

    Toshikazu Saito

Bibliographic Information

  • Book Title: Signal Transduction in Affective Disorders

  • Editors: Hiroki Ozawa, Toshikazu Saito, Naohiko Takahata

  • DOI: https://doi.org/10.1007/978-4-431-68479-4

  • Publisher: Springer Tokyo

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Tokyo 1998

  • Hardcover ISBN: 978-4-431-70210-8Published: 01 January 1998

  • Softcover ISBN: 978-4-431-68481-7Published: 07 March 2012

  • eBook ISBN: 978-4-431-68479-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 146

  • Topics: Clinical Psychology, Psychiatry

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