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Eustachian Tube and Middle Ear Diseases

  • Book
  • © 1992

Overview

Editors:
  1. Peter A. Hall

    1. Department of Histopathology, UMDS, St Thomas’ Hospital, London, UK

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  2. David A. Levison

    1. Department of Histopathology, UMDS, Guy’s Hospital, London, UK

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  3. Nicholas A. Wright

    1. Imperial Cancer Research Fund, Lincoln’s Inn Fields, London, UK
      Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Regulation of the Eukaryotic Cell Cycle

    • R. F. Brooks
    Pages 1-26

  3. Growth Factors, Oncogenes and Tumour Suppressor Genes

    • D. P. Hollywood, N. R. Lemoine
    Pages 27-43

  4. The Kinetic Organisation of Tissues

    • B. Ansari, P. A. Hall
    Pages 45-62

  5. Basic Methods for Assessing Cellular Proliferation

    • R. Dover
    Pages 63-81

  6. Mitosis Counting

    • C. M. Quinn, N. A. Wright
    Pages 83-94

  7. Flow Cytometry

    • R. S. Camplejohn, J. C. Macartney
    Pages 95-111

  8. Measurement of Cell Proliferation Using Bromodeoxyuridine

    • G. D. Wilson, N. J. McNally
    Pages 113-139

  9. The Application of Immunohistochemistry in Assessment of Cellular Proliferation

    • C. C.-W. Yu, A. L. Woods, D. A. Levison
    Pages 141-159

  10. Nucleolar Organiser Regions

    • J. C. E. Underwood
    Pages 161-175

  11. Clinical Aspects of Assessing Cell Proliferation

    • S. M. O’Reilly, M. A. Richards
    Pages 177-191

  12. Cell Proliferation and the Principles of Cancer Therapy

    • W. M. Gregory
    Pages 193-205

  13. Back Matter

    Pages 207-210
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Keywords

About this book

For more than three decades the methods for assessing cell pro­ liferation have been largely the preserve of experimental biologists, and in their hands such techniques have contributed greatly to our understanding of the dynamic organisation of normal and patho­ logical tissues. In recent years, with the advent of novel method­ ologies, there has been increased interest among both pathologists and clinicians, particularly oncologists and others interested in neoplasia, in assessing cell proliferation. This interest has been stimulated by the possibility that indices of cell proliferation may have direct clinical relevance, for example in being useful predictors of outcome in patients with certain forms of malignancy. In addi­ tion, interest in assessing cell proliferation has been fuelled by the tremendous advances in our understanding of the mechanisms of cell proliferation and their deregulation in pathological processes. Consequently, the time is ripe for a monograph critically reviewing the available methods for assessing cell proliferation, their potential and their problems. We have been particularly concerned to present a balanced view of the advantages and disadvantages of different methods currently available for assessing cell proliferation. The assessment of cell proliferation often requires some familiarity with mathematical methods, but in this book we have attempted to keep detailed mathematical analyses to a minimum. We have asked exponents of each of the well-recognised methods to critically review the tech­ niques and the ways in which they may be applied to clinical mate­ rial.

Editors and Affiliations

  • Department of Histopathology, UMDS, St Thomas’ Hospital, London, UK

    Peter A. Hall

  • Department of Histopathology, UMDS, Guy’s Hospital, London, UK

    David A. Levison

  • Imperial Cancer Research Fund, Lincoln’s Inn Fields, London, UK

    Nicholas A. Wright

  • Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK

    Nicholas A. Wright

Bibliographic Information

  • Book Title: Eustachian Tube and Middle Ear Diseases

  • Editors: Peter A. Hall, David A. Levison, Nicholas A. Wright

  • DOI: https://doi.org/10.1007/978-4-431-68287-5

  • Publisher: Springer Tokyo

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Tokyo 1992

  • Softcover ISBN: 978-4-431-68289-9Published: 18 February 2012

  • eBook ISBN: 978-4-431-68287-5Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: IX, 171

  • Number of Illustrations: 23 b/w illustrations

  • Topics: Otorhinolaryngology

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