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Nitric Oxide in the Eye

  • Book
  • © 2000

Overview

Editors:
  1. Satoshi Kashii

    1. Department of Ophthalmology and Visual Sciences Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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  2. Akinori Akaike

    1. Department of Pharmacology Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan

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  3. Yoshihito Honda

    1. Department of Ophthalmology and Visual Sciences Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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  • Covers the whole areas of the eye in relation to nitric oxide

  • Creating an up-to-date review for ophthalmologists as well as research scientists who are interested in this rapidly progressing field

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Table of contents (10 chapters)

  1. Front Matter

    Pages I-IX
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  2. Overview

    1. Front Matter

      Pages 1-1
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    2. Nitric Oxide: Some New Concepts

      • Thom Mittag
      Pages 3-12

  3. Aqueous Dynamics: Mechanisms of Ocular Hypertension and Glaucoma

    1. Front Matter

      Pages 13-13
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    2. Contractility of Trabecular Meshwork and Ciliary Muscle: Modulation by the NO/cGMP System

      • Michael Wiederholt, Friederike Stumpff, Natalie Dürschner
      Pages 15-30

    3. Origin and Function of Nitrergic Nerves in the Human Eye: Morphological Aspects

      • Ernst R. Tamm, Elke Lütjen-Drecoll
      Pages 31-65

  4. Ocular Bloodflow: Ocular Atonomic Neurotransmission

    1. Front Matter

      Pages 67-67
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    2. Cell Culture Studies of Oxygen, Nitric Oxide, and Retinal Pericytes’ Contractile Tone

      • Ivan O. Haefliger, Douglas R. Anderson
      Pages 69-94

    3. Regulation of Retinal Arterial and Arteriolar Tone by Nitric Oxide Derived from Endothelium and Perivascular Nerve

      • Noboru Toda, Megumi Toda, Tomio Okamura
      Pages 95-106

  5. The Uvea: Pathophysiology of Uveitis

    1. Front Matter

      Pages 107-107
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    2. Nitric Oxide in the Iris Sphincter Muscle

      • Hideki Chuman, Tomomi Chuman
      Pages 109-126

    3. Role of Peroxynitrite in Photoreceptor Damage in Experimental Uveitis

      • Guey-Shuang Wu, Narsing A. Rao
      Pages 127-131

  6. The Retina

    1. Front Matter

      Pages 133-133
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    2. Regulation of Inducible Nitric Oxide Synthase in the Retina

      • Olivier Goureau, Violaine Faure, Yvonne De Kozak, Francine Behar-Cohen, Pablo Dighiero, Yves Courtois
      Pages 135-142

    3. Neuronal Protection by Nitric Oxide-Related Species

      • Stuart A. Lipton, Yun-Beom Choi, Nikolaus J. Sucher, H. S.-Vincent Chen
      Pages 143-152

    4. Nitric Oxide and Retinal Ischemia

      • Satoshi Kashii, Yoshihito Honda, Akinori Akaike
      Pages 153-179

  7. Back Matter

    Pages 181-184
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Keywords

About this book

Nitric oxide (NO) is a simple gas with free radical properties. No one would have imagined a role for such a simple substance in the human body. In 1998, R. E Furchgott, E Murad, and L. J. Ignarro received the Nobel prize for their work on NO. Interestingly, Alfred B. Nobel, who invented dynamite by combining nitro­ glycerin with other substances, took nitroglycerin for his chest pain without realizing that NO mediates its action. Now, in addition to its vasodilating action, NO is known to possess many fundamental functions that include neurotrans­ mission, blood pressure control, blood clotting, and immune responses. These diverse functions, conversely, imply that the simple NO molecule may unite neuroscience, physiology, and immunology and may change our understanding of how cells communicate and defend themselves. In this context, the Inter­ national Symposium, Nitric Oxide and Free Radicals, was organized to address current thinking about the widespread distribution and variety of functions of NO in the eye. The symposium was held in Kyoto, Japan, September 28-29 as a Satellite Symposium of the XII International Congress of Eye Research, 1996. The Symposium was the first international gathering of leading scientists and ophthalmologists meeting to present and discuss their most recent results in a specialized area of research, specifically concerning the eye.

Editors and Affiliations

  • Department of Ophthalmology and Visual Sciences Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

    Satoshi Kashii, Yoshihito Honda

  • Department of Pharmacology Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan

    Akinori Akaike

Bibliographic Information

  • Book Title: Nitric Oxide in the Eye

  • Editors: Satoshi Kashii, Akinori Akaike, Yoshihito Honda

  • DOI: https://doi.org/10.1007/978-4-431-67949-3

  • Publisher: Springer Tokyo

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Tokyo 2000

  • Hardcover ISBN: 978-4-431-70287-0Published: 01 August 2000

  • Softcover ISBN: 978-4-431-68017-8Published: 19 September 2011

  • eBook ISBN: 978-4-431-67949-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: IX, 184

  • Topics: Ophthalmology, Human Physiology

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