Multimodality Therapy for Gastric Cancer

1. Front Matter

   Pages I-XIII

   PDF

2. Adjuvant Chemotherapy for Gastric Cancer

   1. Front Matter

      Pages 1-1

      PDF

   2. Success of Adjuvant Chemotherapy Trials for Gastric Cancer

      • Toshifusa Nakajima

      Pages 3-6

   3. Randomized Controlled Trials on Adjuvant Therapy for Gastric Cancer: Japanese Experience

      • Takeshi Sano, Mitsuru Sasako, Hitoshi Katai, Keiichi Maruyama

      Pages 7-16

   4. Multimodality Therapy for Completely Resected (R0) Gastric Cancer (Excluding Japanese Trials)

      • Harold O. Douglass Jr., Hector R. Nava, Judy L. Smith

      Pages 17-26

   5. Meta-Analysis of Adjuvant Chemotherapy Trials for Gastric Cancer at the Cancer Institute Hospital, Tokyo

      • Toshifusa Nakajima, Keiichiro Ohta, Shigekazu Ohyama, Nobuyuki Hamajima

      Pages 27-31

   6. Adjuvant Chemotherapy of Gastric Cancer: JCOG Experience

      • Masatsugu Kitamura, Toshifusa Nakajima, Keiichiro Ohta, Atsushi Nashimoto, Yoshitaka Yamamura, Hiroshi Furukawa et al.

      Pages 32-41

3. Prevention and Control of Peritoneal Dissemination

   1. Front Matter

      Pages 43-43

      PDF

   2. Activated Carbon Particles Adsorbing Mitomycin C Used Against Peritoneal Carcinomatosis in Gastric Cancer

      • Akeo Hagiwara, Toshio Takahashi, Hisakazu Yamagishi

      Pages 45-50

   3. Control of Peritoneal Dissemination with Sequential Methotrexate and 5-Fluorouracil

      • Toshiro Konishi, Tamaki Noie, Kenichi Mafune, Masatoshi Makuuchi, Junji Yoshida

      Pages 51-57

   4. Intraperitoneal Chemotherapy with Mitomycin C or Cisplatin

      • Masahiro Hiratsuka, Hiroshi Furukawa, Takushi Yasuda, Kohei Murata, Terumasa Yamada, Hiroaki Ohigashi et al.

      Pages 58-65

   5. Usefulness of Intraperitoneal Administration of Cisplatin Using a Reservoir for Advanced Gastric Cancer Complicated by Peritoneal Dissemination

      • Keiichiro Ohta, Shigekazu Ohyama, Takashi Takahashi, Toshifusa Nakajima

      Pages 66-70

   6. Peritonectomy as a Treatment Modality for Patients with Peritoneal Dissemination from Gastric Cancer

      • Yutaka Yonemura, Takashi Fujimura, Sachio Fushida, Hideto Fujita, Etsurou Bando, Keizo Taniguchi et al.

      Pages 71-80

4. Control of Liver Metastasis

   1. Front Matter

      Pages 81-81

      PDF

   2. Management of Liver Metastases

      • Yasuaki Arai

      Pages 83-89

   3. Control of Liver Metastasis by Intrahepatic Chemotherapy with Angiotensin II

      • Yoshiaki Iwasaki, Kuniyoshi Arai, Manabu Ohashi, Toshio Takahashi, Masatsugu Kitamura

      Pages 90-94

5. Control of Distant Lymph Node Metastasis

   1. Front Matter

      Pages 95-95

      PDF

   2. Neoadjuvant Chemotherapy with FLEP Regimen for Incurable Gastric Cancer

      • Toshifusa Nakajima, Keiichiro Ohta, Shou Ishihara, Shigekazu Ohyama, Mitsumasa Nishi, Yasuhiko Ohashi et al.

      Pages 97-103

   3. Case Report of Pathological Complete Remission with FLEP Therapy

      • Shigekazu Ohyama, Osamu Komatsu, Toshifusa Nakajima, Keiichiro Ohta, Takashi Takahashi, Akio Yanagisawa

      Pages 104-107

   4. Neoadjuvant Chemotherapy with FLEP Therapy for Advanced Gastric Cancer: Evaluation of Intraaortic and Intravenous FLEP Infusions

      • Sun-Kyo Song, Sang-Woon Kim

      Pages 108-112

Recent clinical trials of adjuvant therapy for gastric cancer in Japan have shown improved survival benefits, but the results have been considered controversial and have been viewed with some skepticism in the West. Until now, the efforts of Japanese surgical oncologists in multimodality therapy have not been fully understood because they have not been adequately reported in English. This volume now presents the experience and expertise of Japanese surgeons who utilize preoperative or intraoperative chemotherapy, or a combination of systemic and regional chemotherapy. Their collected work provides valuable insight in the Japanese perspective and success in treating gastric cancer. Included in the appendix is an extensive tabular analysis of the gastric cancer database at the Cancer Institute Hospital of Tokyo. Probably the largest such database in the world from a single institution, the analyses present the state of the art in treatment of gastric cancer.

• adjuvant therapy
• angiogenesis
• cancer
• carcinoma
• clinical trial
• gastric cancer
• gene therapy
• liver
• metastasis
• prevention
• abdominal surgery

• Cancer Institute Hospital, Tokyo, Japan

  Toshifusa Nakajima

• The First Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan

  Toshiharu Yamaguchi

Policies and ethics