Editors:
Describes functions of ?-amino acids comprehensively
Chapters are organically arranged for readers’ clearer understanding
Written by the world’s leading scientists in the field
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Table of contents (22 chapters)
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Front Matter
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Detection of d-Amino Acids
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Front Matter
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Physiological Functions and Pathophysiology of d-Serine
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Front Matter
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Function of d-Aspartate
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Front Matter
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d-Amino Acid Residues in Proteins
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Front Matter
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About this book
This book presents a comprehensive overview of the roles of ᴅ-amino acids and latest research findings, to reveal their fascinating aspects and to facilitate better understanding of their important roles in physiology and diseases. It also provides useful hints for the development of drugs and functional foods. ᴅ-Amino acids were once called unnatural amino acids and were considered to be insignificant for eukaryotes especially in mammals. However, different ᴅ-amino acids have been revealed to be distributed in various mammalian tissues and to bear important physiological roles. For example, ᴅ-serine is implicated in memory formation and learning, and its abnormal concentration in tissues have been reported in neurological diseases such as schizophrenia and amyotrophic lateral sclerosis. ᴅ-Aspartate is found in a variety of mammalian tissues, particularly in the central nervous system and the genitals. ᴅ-Aspartate facilitates the endocrine secretion of prolactin, inhibits the secretion of melatonin, and plays a peculiar role in the control of reproductive functions in mammals, including the stimulation of testosterone synthesis. Written by the leading scientists in the field, this book is a valuable source of information for researchers in biochemistry, physiology, and neuroscience, as well as in the pharmaceutical and food industries.
Editors and Affiliations
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Department of Applied Molecular Biosciences Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
Tohru Yoshimura
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Department of Psychiatry and Behavioral Sciences Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
Toru Nishikawa
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Laboratory of Biomolecular Science Department of Pharmaceutical Life Sciences, Kitasato University, Tokyo, Japan
Hiroshi Homma
Bibliographic Information
Book Title: D-Amino Acids
Book Subtitle: Physiology, Metabolism, and Application
Editors: Tohru Yoshimura, Toru Nishikawa, Hiroshi Homma
DOI: https://doi.org/10.1007/978-4-431-56077-7
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Japan 2016
Hardcover ISBN: 978-4-431-56075-3Published: 05 September 2016
Softcover ISBN: 978-4-431-56772-1Published: 12 June 2018
eBook ISBN: 978-4-431-56077-7Published: 25 August 2016
Edition Number: 1
Number of Pages: IX, 357
Number of Illustrations: 42 b/w illustrations, 31 illustrations in colour
Topics: Biochemistry, general