Overview
Provides the most up-to-date summary of cutting-edge research on chronic inflammation
Clarifies the molecular link between chronic inflammation and various diseases including cancer, cardiovascular diseases, and diabetes mellitus
Provides insights into early detection and therapeutic intervention in chronic inflammation
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Table of contents (52 chapters)
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Front Matter
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Basic Mechanisms Underlying Induction, Progression, and Resolution of Chronic Inflammation
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Front Matter
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Imaging Analyses of Chronic Inflammation
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Front Matter
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Keywords
About this book
This book provides readers with the most up-to-date information on cutting-edge research concerning chronic inflammation. We now know that when inflammation becomes chronic, it acts as a strong disease-promoting factor in a variety of disorders including arteriosclerosis, obesity, cancer, and Alzheimer disease. Chronic inflammation is hence called as the “silent killer”; it upsets the body’s homeostatic mechanism insidiously. In spite of these developments, we know very little about the mechanism underlying chronic inflammation. Particularly, we do not know precisely what induces chronic inflammation or what promotes its prolongation in a spatiotemporal framework. Neither do we have clear knowledge about how chronic inflammation destroys various tissues or how it predisposes individuals to many different diseases. To make the situation worse, we have no effective treatment against chronic inflammation.
Since 2010, two major research programs (CREST and PRESTO) aimed at clarifying the mechanisms underlying chronic inflammation were launched in Japan, and investigators of different research areas with a brilliant track record were selected by their research proposals. Subsequently they have made their best efforts to answer the conundrum concerning chronic inflammation. This book is a compendium of such research efforts. In each chapter, the CREST- or PRESTO-funded researchers summarize their original work concerning mechanisms of induction, progression, or resolution underlying chronic inflammation. The most emphasized characteristic is the molecular aspect of chronic inflammation. The book thus presents the most recent progress made in the molecular understanding of chronic inflammation.
Editors and Affiliations
About the editors
Masayuki Miyasaka, MD, PhD
Specially-Appointed Professor, IPBS, Osaka University,
Professor Emeritus, Osaka University,
FiDiPro Professor, Academy of Finland,
JST-CREST “Chronic Inflammation” Research Supervisor
Kiyoshi Takatsu, PhD
Director, Toyama Prefectural Institute for Pharmaceutical Research,
Visiting Professor, University of Toyama,
Professor Emeritus, The University of Tokyo,
JST-PRESTO “Chronic Inflammation” Research Supervisor
Bibliographic Information
Book Title: Chronic Inflammation
Book Subtitle: Mechanisms and Regulation
Editors: Masayuki Miyasaka, Kiyoshi Takatsu
DOI: https://doi.org/10.1007/978-4-431-56068-5
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Japan 2016
Hardcover ISBN: 978-4-431-56066-1Published: 02 November 2016
Softcover ISBN: 978-4-431-56769-1Published: 29 June 2018
eBook ISBN: 978-4-431-56068-5Published: 01 November 2016
Edition Number: 1
Number of Pages: XI, 702
Number of Illustrations: 28 b/w illustrations, 139 illustrations in colour
Topics: Immunology, Human Physiology, Cancer Research, Cardiology