Bile Acids in Gastroenterology

1. Front Matter

   Pages i-viii

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2. Biological Aspects of Bile Acids

   1. Front Matter

      Pages 1-1

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   2. Metabolism of Bile Acids

      • Hajime Takikawa

      Pages 3-8

   3. Hepatobiliary Transport of Bile Acids

      • Tatehiro Kagawa

      Pages 9-25

   4. Intestinal Digestion and Absorption

      • Akira Honda, Tadashi Ikegami, Yasushi Matsuzaki

      Pages 27-41

   5. Nuclear Receptor Regulation

      • Makoto Makishima

      Pages 43-59

   6. Bile Acid as Therapeutic Agents

      • Yoshihide Yamanashi, Tappei Takada, Hiroshi Suzuki

      Pages 61-90

3. Bile Acids and Diseases

   1. Front Matter

      Pages 91-91

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   2. Bile Acids and Gallstones: Epidemiology, Pathogenesis, Diagnosis, and Management

      • Susumu Tazuma

      Pages 93-107

   3. Bile Acids and Cholestatic Liver Disease 1: Primary Biliary Cholangitis (PBC)

      • Atsushi Tanaka

      Pages 109-119

   4. Bile Acids and Cholestatic Liver Disease 2: Primary Sclerosing Cholangitis

      • Takahiro Nakazawa

      Pages 121-134

   5. Bile Acids and Cholestatic Liver Disease 3: Inborn Errors of Bile Acid Synthesis

      • Hiroshi Nittono, Akihiko Kimura, Hajime Takei, Takao Kurosawa, Takashi Iida

      Pages 135-144

   6. Bile Acids and NAFLD/NASH

      • Tsuneo Kitamura, Sumio Watanabe

      Pages 145-155

   7. Bile Acids and Viral Hepatitis and Hepatocellular Carcinoma

      • Yasuaki Takeyama, Shotaro Sakisaka

      Pages 157-168

   8. Bile Acids and Pancreatic Disease

      • Morihisa Hirota, Tooru Shimosegawa

      Pages 169-176

   9. Bile Acids and Esophageal Cancer

      • Juntaro Matsuzaki, Hidekazu Suzuki

      Pages 177-184

   10. Bile Acid and Colorectal Cancer

       • Michiaki Unno

       Pages 185-192

   11. Bile Acids and Metabolic Syndrome

       • Hiroki Taoka, Mitsuhiro Watanabe

       Pages 193-209

This book examines the biological aspects of bile acid analysis and their clinical applications, providing readers with an overview of cutting-edge discussions on Bile Acid research and diseases. It begins with detailed discussions on the biological aspects of bile acid, with chapters examining bile acid from various perspectives, from its metabolism to its use in therapeutic agents. Subsequent chapters focus on diseases involving bile acid abnormalities, and specific applications are addressed concerning gallstones, cholestatic liver disease, NAFLD/NASH, hepatitis, pancreatitis, esophageal cancer and colon cancer. In keeping with the book’s integrated approach, the Editor has gathered a broad range of eminent scholars and practitioners to provide a comprehensive review of modern bile acid research. The book offers clinical physicians, basic researchers and postgraduate students essential insights into cutting-edge research and paves the way for further research.

• Cholesterol
• Colon Cancer
• Esophageal Cancer
• Metabolism
• NAFLD/NASH
• Nuclear Receptor Regulation
• Transport
• metabolic disease
• hepatology

• Department of General Medicine, Hiroshima University Hospital, Hiroshima, Japan

  Susumu Tazuma

• Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan

  Hajime Takikawa

Dr.Susumu Tazuma, Department of General Medicine, Hiroshima University Hospital

Dr. Hajime Takikawa, Department of Medicine, Teikyo University School of Medicine

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