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Cell Therapy Against Cerebral Stroke

Comprehensive Reviews for Translational Researches and Clinical Trials

  • Book
  • © 2017

Overview

Editors:
  1. Kiyohiro Houkin

    1. Hokkaido University Graduate School of M, Department of Neurosurgery, Sapporo, Japan

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  2. Koji Abe

    1. Okayama University Graduate School of Me, Department of Neurology, Okayama, Japan

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  3. Satoshi Kuroda

    1. Graduate School of Medicine and Pharmace, Department of Neurosurgery, Toyama, Japan

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  • Describes the current state of knowledge on cell therapy for cerebral stroke

  • Addresses comprehensive topics in both basic research and clinical trials

  • Written by experts with considerable personal experience in neurosurgery and neurology

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-x
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  2. Optimal Cell Cources

    1. Front Matter

      Pages 1-1
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    2. Bone Marrow-Derived Mononuclear Cells

      • Satoshi Suda
      Pages 3-14

    3. Cell Therapy for Ischemic Stroke with Bone Marrow Stromal Cells

      • Satoshi Kuroda, Hideo Shichinohe, Kiyohiro Houkin
      Pages 15-25

    4. Neural Stem Cells/Neuronal Progenitor Cells

      • Nobutaka Horie
      Pages 27-37

    5. iPS Cells and iN Cells

      • Toru Yamashita, Koji Abe
      Pages 39-46

  3. Translational Researches

    1. Front Matter

      Pages 47-47
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    2. Cell Culture

      • Masaki Ito, Kiyohiro Houkin
      Pages 49-72

    3. Route, Cell Dose, and Timing

      • Masahito Kawabori
      Pages 73-85

    4. Role of Biomaterials as Scaffolding in Cell Therapy for Stroke

      • Toshiya Osanai
      Pages 87-99

    5. In Vivo Cell Tracking Techniques for Applications in Central Nervous System Disorders

      • Taku Sugiyama, Satoshi Kuroda, Kiyohiro Houkin
      Pages 101-110

    6. Functional Bio-imaging

      • Hisayasu Saito, Michiyuki Miyamoto, Hideo Shichinohe, Kiyohiro Houkin, Satoshi Kuroda
      Pages 111-119

  4. Clinical Trials

    1. Front Matter

      Pages 121-121
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    2. Review of Previous Clinical Trials and Guidelines of Cell Therapy

      • Hideo Shichinohe
      Pages 123-133

    3. Intravenous Autologous Bone Marrow Mononuclear Cell Transplantation for Stroke Patients

      • Yukiko Kasahara, Tomohiro Matsuyama, Akihiko Taguchi
      Pages 135-146

    4. Mesenchymal Stem Cells

      • Masanori Sasaki, Osamu Honmou
      Pages 147-156
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Keywords

About this book

This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke.
Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity.

Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy.
The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.

Editors and Affiliations

  • Hokkaido University Graduate School of M, Department of Neurosurgery, Sapporo, Japan

    Kiyohiro Houkin

  • Okayama University Graduate School of Me, Department of Neurology, Okayama, Japan

    Koji Abe

  • Graduate School of Medicine and Pharmace, Department of Neurosurgery, Toyama, Japan

    Satoshi Kuroda

About the editors

Dr. Kiyohiro Houkin, Department of Neurosurgery, Hokkaido UniversityDr. Koji Abe, Department of Neurology, Okayama University

Dr. Satoshi Kuroda, Department of Neurosurgery, University of Toyama

Bibliographic Information

  • Book Title: Cell Therapy Against Cerebral Stroke

  • Book Subtitle: Comprehensive Reviews for Translational Researches and Clinical Trials

  • Editors: Kiyohiro Houkin, Koji Abe, Satoshi Kuroda

  • DOI: https://doi.org/10.1007/978-4-431-56059-3

  • Publisher: Springer Tokyo

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Japan KK 2017

  • Hardcover ISBN: 978-4-431-56057-9Published: 13 January 2017

  • Softcover ISBN: 978-4-431-56766-0Published: 13 July 2018

  • eBook ISBN: 978-4-431-56059-3Published: 06 January 2017

  • Edition Number: 1

  • Number of Pages: X, 156

  • Number of Illustrations: 4 b/w illustrations, 11 illustrations in colour

  • Topics: Neurosurgery, Neurology, Regenerative Medicine/Tissue Engineering

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