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Kawasaki Disease

Current Understanding of the Mechanism and Evidence-Based Treatment

  • Book
  • © 2017

Overview

Editors:
  1. Ben Tsutomu Saji

    1. Advanced and Integrated Cardiovascular Research Course in the Young and Adolescence, Toho University, Tokyo, Japan

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  2. Jane W. Newburger

    1. Boston Children’s Hospital, Harvard Medical School, Department of Cardiology, Boston, USA

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  3. Jane C. Burns

    1. Department of Pediatrics, Rady Children’s Hospital, University of California San Diego School of Medicine, La Jolla, USA

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  4. Masato Takahashi

    1. Heart Center , Seattle Childrens Hospital, Seattle, USA

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  • Covers all essential information for clinicians, including basic science and practical treatment

  • Discusses the latest advances using anti-cytokine therapies

  • Compiled by an international team of experts

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Table of contents (46 chapters)

  1. Front Matter

    Pages i-xix
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  2. Basic Research

    1. Front Matter

      Pages 1-1
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    2. The History of Kawasaki Disease: A Personal Perspective

      • Marian E. Melish
      Pages 3-9

    3. Histopathology of Coronary Arteritis in Acute Kawasaki Disease and Murine Systemic Vasculitis Induced by Candida Albicans Cell Wall Polysaccharide

      • Toshiaki Oharaseki, Yuki Yokouchi, Yasunori Enomoto, Kei Takahashi
      Pages 11-16

    4. Histopathological Characteristics of Noncardiac Organs in Kawasaki Disease

      • Kei Takahashi, Toshiaki Oharaseki, Yuki Yokouchi, Yoshinori Enomoto
      Pages 17-22

    5. Identification of Novel Kawasaki Disease Susceptibility Genes by Genome-Wide Association Studies

      • Yoshihiro Onouchi
      Pages 23-29

    6. Immunological Abnormalities and Use of Biomarkers and Cytokines to Predict the Severity of Kawasaki Disease

      • Jun Abe
      Pages 31-37

    7. Pathophysiology of Kawasaki Disease

      • Anne H. Rowley, Stanford T. Shulman, Jan M. Orenstein
      Pages 39-44

    8. Update on Pathogenesis: Lessons Learned from Animal Models of Disease

      • Trang T. Duong, Rae S. M. Yeung
      Pages 45-51

    9. The Climate–KD Link

      • Jane C. Burns, Daniel R. Cayan
      Pages 53-57

    10. Kawasaki Disease Shock Syndrome

      • Ming-Tai Lin, Mei-Hwan Wu
      Pages 59-63

    11. Future Directions in Kawasaki Disease Research

      • Jane C. Burns
      Pages 65-69

  4. Medical Treatment

    1. Front Matter

      Pages 95-95
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    2. Overview of Medical Treatment

      • Jane W. Newburger
      Pages 97-101

    3. Overview of the New Japanese Guideline2012 for the Medical Treatment of Acute Stage of Kawasaki Disease

      • Ben Tsutomu Saji, Tohru Kobayashi
      Pages 103-167
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Keywords

About this book

This book provides the most up-to-date information on the clinical research into and medical management of Kawasaki Disease, and opens the door for new pathological insights. Its nearly 50 sections cover basic research, genetic backgrounds, bacterial and　biological　evidence, and medical　treatment　with　intravenous　immunoglobulin, steroids, and recent anti-cytokine approaches. It offers an invaluable resource for general pediatricians, pediatric and adult cardiologists, pediatric cardiac surgeons, infectious disease specialists, pediatric rheumatologists, epidemiologists, and basic researchers in these disciplines.

Editors and Affiliations

  • Advanced and Integrated Cardiovascular Research Course in the Young and Adolescence, Toho University, Tokyo, Japan

    Ben Tsutomu Saji

  • Boston Children’s Hospital, Harvard Medical School, Department of Cardiology, Boston, USA

    Jane W. Newburger

  • Department of Pediatrics, Rady Children’s Hospital, University of California San Diego School of Medicine, La Jolla, USA

    Jane C. Burns

  • Heart Center , Seattle Childrens Hospital, Seattle, USA

    Masato Takahashi

About the editors

Dr. Ben Tsutomu Saji, First Department of Pediatrics, Toho University Omori Medical Center, Tokyo, Japan. 

Dr. Jane W. Newburger, Harvard Medical School, Department of Cardiology, Boston Children's Hospital, Boston, USA

Dr. Jane C. Burns, Department of Pediatrics, Rady Children’s Hospital, University of California San Diego School of Medicine, La Jolla, USA

Dr. Masato Takahashi, Heart Center, Seattle Children's Hospital, Seattle, USA

Bibliographic Information

  • Book Title: Kawasaki Disease

  • Book Subtitle: Current Understanding of the Mechanism and Evidence-Based Treatment

  • Editors: Ben Tsutomu Saji, Jane W. Newburger, Jane C. Burns, Masato Takahashi

  • DOI: https://doi.org/10.1007/978-4-431-56039-5

  • Publisher: Springer Tokyo

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Japan 2017

  • Hardcover ISBN: 978-4-431-56037-1Published: 07 September 2016

  • Softcover ISBN: 978-4-431-56761-5Published: 15 June 2018

  • eBook ISBN: 978-4-431-56039-5Published: 27 August 2016

  • Edition Number: 1

  • Number of Pages: XIX, 552

  • Number of Illustrations: 39 b/w illustrations, 38 illustrations in colour

  • Topics: Pediatrics, Cardiology, Immunology

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