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C-Type Lectin Receptors in Immunity

  • Book
  • © 2016

Overview

Editors:
  1. Sho Yamasaki

    1. Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

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  • Provides detailed update on individual C-type
  • written by outstanding experts of the field
  • Is the first comprehensive book on C-type lectin receptors and their signaling

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About this book

The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-vi
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  2. ITAM-Coupled Activating Receptors

    1. Front Matter

      Pages 1-1
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    2. Dectin-2 in Antimicrobial Immunity and Homeostasis

      • Rikio Yabe, Shinobu Saijo
      Pages 3-13

    3. Pathogen-Sensing by Mincle: Function and Molecular Aspects

      • Masahiro Nagata, Zakaria Omahdi, Sho Yamasaki
      Pages 15-34

    4. The DAP12-Associated Myeloid C-Type Lectin 5A (CLEC5A)

      • Shie-Liang Hsieh
      Pages 35-48

  3. HemITAM-Bearing Receptors

    1. Front Matter

      Pages 49-49
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    2. Dectin-1 (CLEC7A, BGR, CLECSF12)

      • Patawee Asamaphan, Janet A. Willment, Gordon D. Brown
      Pages 51-63

    3. DNGR-1, an F-Actin-Binding C-Type Lectin Receptor Involved in Cross-Presentation of Dead Cell-Associated Antigens by Dendritic Cells

      • Pavel Hanč, Salvador Iborra, Santiago Zelenay, Janneke van Blijswijk, David Sancho, Caetano Reis e Sousa
      Pages 65-81

    4. C-Type Lectin-Like Receptor 2 (CLEC-2)

      • Katsue Suzuki-Inoue
      Pages 83-98

  4. ITIM-Bearing Receptors

    1. Front Matter

      Pages 99-99
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    2. Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor

      • Tomonori Kaifu, Yoichiro Iwakura
      Pages 101-113

    3. Regulation and Function of the Inhibitory C-Type Lectin Clec12A/MICL

      • Konstantin Neumann, Jürgen Ruland
      Pages 115-126

  5. Other Receptors and Related Topics

    1. Front Matter

      Pages 127-127
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    2. DC-SIGN in Infection and Immunity

      • Joris K. Sprokholt, Ronald J. Overmars, Teunis B. H. Geijtenbeek
      Pages 129-150

    3. LOX-1 and Immunity

      • Anja Hofmann, Tatsuya Sawamura, Henning Morawietz
      Pages 151-163

    4. MGL/CD301 as a Unique C-Type Lectin Expressed on Dendritic Cells and Macrophages

      • Kaori Denda-Nagai, Tatsuro Irimura
      Pages 165-178

    5. Structural Aspects of C-Type Lectin Receptors

      • Atsushi Furukawa, Shunsuke Kita, Takashi Tadokoro, Hideo Fukuhara, Katsumi Maenaka
      Pages 179-190

    6. The Ligands of C-Type Lectins

      • Amy J. Foster, Jessie H. Bird, Mattie S. M. Timmer, Bridget L. Stocker
      Pages 191-215
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Editors and Affiliations

  • Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

    Sho Yamasaki

About the editor

Sho Yamasaki, PhD, Professor at Kyushu University

Bibliographic Information

  • Book Title: C-Type Lectin Receptors in Immunity

  • Editors: Sho Yamasaki

  • DOI: https://doi.org/10.1007/978-4-431-56015-9

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Japan 2016

  • Hardcover ISBN: 978-4-431-56013-5Published: 31 March 2016

  • Softcover ISBN: 978-4-431-56753-0Published: 25 April 2018

  • eBook ISBN: 978-4-431-56015-9Published: 22 March 2016

  • Edition Number: 1

  • Number of Pages: VI, 215

  • Number of Illustrations: 23 b/w illustrations, 6 illustrations in colour

  • Topics: Immunology, Biochemistry, general, Pharmaceutical Sciences/Technology

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